MetaADEDB 2.0 @ LMMD
trospium chloride
(RVCSYOQWLPPAOA-DHWZJIOFSA-M)
Structure
SMILES
O=C(C(c1ccccc1)(c1ccccc1)O)OC1C[C@@H]2CC[C@H](C1)[N+]12CCCC1.[Cl-]
Molecular Formula:
C25H30ClNO3
Molecular Weight:
427.964
Log P:
0.7325
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
46.53
CAS Number(s):
10405-02-4
Synonym(s)
1.
trospium chloride
2.
Ceris
3.
Spasmex
4.
Spasmo-Rhoival TC
5.
Spasmo-Urgenin
6.
Spasmo-Urgenin TC
7.
Spasmo-lyt
8.
Spasmolyt
9.
Trospi
10.
Uraplex
11.
Uraton
12.
azoniaspiro compound XVII
13.
azoniaspiro(3 alpha-benziloyloxynortropane-8,1'- pyrrolidine) chloride
External Link(s)
MeSHC003330
PubChem Compound5284631
ChEBI32270
CHEMBLCHEMBL3084748
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 51OFFSIDES
US FAERS
2ConstipationFAERS: 49US FAERS
3DizzinessFAERS: 15US FAERS
4DysuriaFAERS: 12US FAERS
5Urinary RetentionFAERS: 12US FAERS
6HeadacheFAERS: 10US FAERS
7VomitingFAERS: 10US FAERS
8FatigueFAERS: 8OFFSIDES
US FAERS
9Abdominal discomfortFAERS: 7OFFSIDES
US FAERS
10AstheniaFAERS: 7OFFSIDES
US FAERS
11PainFAERS: 7US FAERS
12PruritusFAERS: 7US FAERS
13Urinary IncontinenceFAERS: 715977961CTD
US FAERS
14NauseaFAERS: 6OFFSIDES
US FAERS
15DyspepsiaFAERS: 5US FAERS
16ArthralgiaFAERS: 4US FAERS
17PalpitationsFAERS: 4US FAERS
18Product substitution issueFAERS: 4US FAERS
19SomnolenceFAERS: 4US FAERS
20Urinary tract infectionFAERS: 4US FAERS
21Visual ImpairmentFAERS: 4US FAERS
22Weight decreasedFAERS: 4US FAERS
23Abdominal PainFAERS: 3US FAERS
24Chest PainFAERS: 3US FAERS
25DisorientationFAERS: 3US FAERS
26Feeling abnormalFAERS: 3US FAERS
27FlatulenceFAERS: 3OFFSIDES
US FAERS
28HypersensitivityFAERS: 3US FAERS
29MyalgiaFAERS: 3US FAERS
30AlopeciaFAERS: 2US FAERS
31AnxietyFAERS: 2US FAERS
32Back PainFAERS: 2US FAERS
33Burning sensationFAERS: 2US FAERS
34CystitisFAERS: 2US FAERS
35Dental cariesFAERS: 2OFFSIDES
US FAERS
36Depressed Level of ConsciousnessFAERS: 2US FAERS
37Drug administration errorFAERS: 2US FAERS
38EructationFAERS: 2US FAERS
39Eye painFAERS: 2OFFSIDES
US FAERS
40Gastrointestinal motility disorderFAERS: 2US FAERS
41Heat StrokeFAERS: 2OFFSIDES
US FAERS
42IncontinenceFAERS: 2OFFSIDES
US FAERS
43LethargyFAERS: 2US FAERS
44MalaiseFAERS: 2US FAERS
45Oropharyngeal painFAERS: 2US FAERS
46Product physical issueFAERS: 2US FAERS
47SyncopeFAERS: 2US FAERS
48ThrombosisFAERS: 2US FAERS
49TremorFAERS: 2US FAERS
50Unevaluable eventFAERS: 2OFFSIDES
US FAERS
51Unresponsive to stimuliFAERS: 2US FAERS
52Wrong technique in product usage processFAERS: 2US FAERS
53Accidental drug intake by childFAERS: 1US FAERS
54Accidental overdoseFAERS: 1US FAERS
55Adverse eventFAERS: 1US FAERS
56AgeusiaFAERS: 1US FAERS
57AmnesiaFAERS: 1US FAERS
58AneurysmFAERS: 1US FAERS
59AngioedemaFAERS: 1OFFSIDES
US FAERS
60AnosmiaFAERS: 1US FAERS
61Anticholinergic SyndromeFAERS: 1US FAERS
62ArthritisFAERS: 1US FAERS
63Bladder spasmFAERS: 1US FAERS
64Blood alkaline phosphatase increasedFAERS: 1US FAERS
65Blood cholesterol abnormalFAERS: 1US FAERS
66Bone painFAERS: 1US FAERS
67ChillsFAERS: 1US FAERS
68ColitisFAERS: 1OFFSIDES
US FAERS
69CryingFAERS: 1US FAERS
70DeafnessFAERS: 1US FAERS
71Deep Vein ThrombosisFAERS: 1US FAERS
72DehydrationFAERS: 1US FAERS
73Disease recurrenceFAERS: 1US FAERS
74Documented hypersensitivity to administered productFAERS: 1US FAERS
75Drug effect incompleteFAERS: 1US FAERS
76Drug effect variableFAERS: 1US FAERS
77Drug prescribing errorFAERS: 1US FAERS
78Dry skinFAERS: 1US FAERS
79ErythemaFAERS: 1OFFSIDES
US FAERS
80Expired drug administeredFAERS: 1US FAERS
81Expired product administeredFAERS: 1US FAERS
82Eye BurnsFAERS: 1US FAERS
83FlushingFAERS: 1US FAERS
84Impaired driving abilityFAERS: 1US FAERS
85Inappropriate schedule of drug administrationFAERS: 1US FAERS
86InfectionFAERS: 1OFFSIDES
US FAERS
87Intentional drug misuseFAERS: 1US FAERS
88Intestinal ObstructionFAERS: 1US FAERS
89Intestinal PerforationFAERS: 1US FAERS
90Joint stiffnessFAERS: 1US FAERS
91Mastication disorderFAERS: 1OFFSIDES
US FAERS
92Musculoskeletal stiffnessFAERS: 1US FAERS
93MydriasisFAERS: 1US FAERS
94NasopharyngitisFAERS: 1US FAERS
95NocturiaFAERS: 1OFFSIDES
US FAERS
96OliguriaFAERS: 1US FAERS
97PallorFAERS: 1OFFSIDES
US FAERS
98Penile size reducedFAERS: 1US FAERS
99Pharyngolaryngeal PainFAERS: 1US FAERS
100PolyuriaFAERS: 1OFFSIDES
US FAERS
101Productive CoughFAERS: 1US FAERS
102Rash erythematousFAERS: 1US FAERS
103Renal painFAERS: 1US FAERS
104RhabdomyolysisFAERS: 1OFFSIDES
US FAERS
105Sinus TachycardiaFAERS: 1US FAERS
106Skin WrinklingFAERS: 1US FAERS
107Stevens-Johnson SyndromeFAERS: 125811541CTD
US FAERS
108TachycardiaFAERS: 1US FAERS
109Temperature intoleranceFAERS: 1OFFSIDES
US FAERS
110Therapy responderFAERS: 1US FAERS
111Throat irritationFAERS: 1US FAERS
112TinnitusFAERS: 1OFFSIDES
US FAERS
113Tooth LossFAERS: 1OFFSIDES
US FAERS
114UrticariaFAERS: 1US FAERS
115VasculitisFAERS: 1US FAERS
116Visual disturbanceFAERS: 1US FAERS
117Vulvovaginal burning sensationFAERS: 1US FAERS
118Abdominal strangulated herniaOFFSIDES
119Abnormal visionOFFSIDES
120Acquired porphyriaOFFSIDES
121Activities of daily living impairedOFFSIDES
122Acute Coronary SyndromeOFFSIDES
123Acute myocardial infarctionOFFSIDES
124Acute prerenal failureOFFSIDES
125AdenocarcinomaOFFSIDES
126AgraphiaOFFSIDES
127AlveolitisOFFSIDES
128AnhedoniaOFFSIDES
129AnuriaOFFSIDES
130Application site rashOFFSIDES
131Application site ulcerOFFSIDES
132ArthropathyOFFSIDES
133AscitesOFFSIDES
134AspergillosisOFFSIDES
135AsphyxiaOFFSIDES
136AsthmaOFFSIDES
137Atrial tachycardiaOFFSIDES
138AutomatismOFFSIDES
139Bilateral hydronephrosisOFFSIDES
140BlepharitisOFFSIDES
141Blood albumin decreasedOFFSIDES
142Blood glucose abnormalOFFSIDES
143Blood sodiumOFFSIDES
144Blurred visionOFFSIDES
145Body temperature fluctuationOFFSIDES
146Bone fragmentationOFFSIDES
147Breast cancer recurrentOFFSIDES
148Bronchoalveolar LavageOFFSIDES
149Bulbar palsyOFFSIDES
150Cardiac ablationOFFSIDES
151Cataract operationOFFSIDES
152CatatoniaOFFSIDES
153Catheter site painOFFSIDES
154CellulitisOFFSIDES
155Central venous catheter removalOFFSIDES
156Cervical cord compressionOFFSIDES
157Cervical dysplasiaOFFSIDES
158Cervical laser therapyOFFSIDES
159Cervical myelopathyOFFSIDES
160Cholecystitis infectiveOFFSIDES
161Compression fractureOFFSIDES
162Creatinine renal clearance decreasedOFFSIDES
163DebridementOFFSIDES
164DemyelinationOFFSIDES
165Device breakageOFFSIDES
166Device related infectionOFFSIDES
167DiarrheaOFFSIDES
168DiverticulumOFFSIDES
169Drug toxicityOFFSIDES
170Drug withdrawal headacheOFFSIDES
171DysgeusiaOFFSIDES
172Endodontic procedureOFFSIDES
173EndometriosisOFFSIDES
174Enteritis necroticansOFFSIDES
175EpistaxisOFFSIDES
176Erectile dysfunctionOFFSIDES
177Erosive gastritisOFFSIDES
178EscharOFFSIDES
179Escherichia infectionOFFSIDES
180Febrile NeutropeniaOFFSIDES
181Flank PainOFFSIDES
182Fluid overloadOFFSIDES
183Food aversionOFFSIDES
184FormicationOFFSIDES
185GangreneOFFSIDES
186GastroenteritisOFFSIDES
187Gastrointestinal infectionOFFSIDES
188Gastrointestinal toxicityOFFSIDES
189Granulomatous liver diseaseOFFSIDES
190HemiparesisOFFSIDES
191Hernia obstructiveOFFSIDES
192HiccoughOFFSIDES
193HyperventilationOFFSIDES
194Immune reconstitution syndromeOFFSIDES
195ImmunosuppressionOFFSIDES
196Impaired work abilityOFFSIDES
197Injection site erythemaOFFSIDES
198Injection site pruritusOFFSIDES
199Injection site warmthOFFSIDES
200Intention tremorOFFSIDES
201Joint prosthesis userOFFSIDES
202Kidney FailureOFFSIDES
203LymphoceleOFFSIDES
204MalabsorptionOFFSIDES
205MeningiomaOFFSIDES
206Multiple SclerosisOFFSIDES
207Multiple sclerosis relapseOFFSIDES
208MyotoniaOFFSIDES
209Neurogenic BowelOFFSIDES
210NoduleOFFSIDES
211Nonspecific reactionOFFSIDES
212OsteomyelitisOFFSIDES
213OsteopeniaOFFSIDES
214OsteoporosisOFFSIDES
215Pancreatic InsufficiencyOFFSIDES
216PancreatitisOFFSIDES
217PeriodontitisOFFSIDES
218PlasmacytomaOFFSIDES
219PleurisyOFFSIDES
220Poor quality sleepOFFSIDES
221Post procedural complicationOFFSIDES
222Posterior CapsulotomyOFFSIDES
223Posterior capsule opacificationOFFSIDES
224Postoperative wound complicationOFFSIDES
225Prostatic ObstructionOFFSIDES
226PyelonephritisOFFSIDES
227Renal cystOFFSIDES
228SacroiliitisOFFSIDES
229Septic ShockOFFSIDES
230SeromaOFFSIDES
231Sick Sinus SyndromeOFFSIDES
232Skin lacerationOFFSIDES
233Skin lesionOFFSIDES
234Stem cell transplantOFFSIDES
235StressOFFSIDES
236Synovial CystOFFSIDES
237Therapeutic response unexpected with drug substitutionOFFSIDES
238Tooth ExtractionOFFSIDES
239TracheobronchitisOFFSIDES
240Umbilical herniaOFFSIDES
241Ureterostomy site discomfortOFFSIDES
242Vascular ruptureOFFSIDES
243Ventricular FibrillationOFFSIDES
244VertebroplastyOFFSIDES
245Vitamin A DeficiencyOFFSIDES
246Weight GainOFFSIDES
247Wound dehiscenceOFFSIDES
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