MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

tandospirone

(CEIJFEGBUDEYSX-FZDBZEDMSA-N)

Structure

SMILES: O=C1N(CCCCN2CCN(CC2)c2ncccn2)C(=O)[C@@H]2[C@H]1[C@H]1CC[C@@H]2C1
Type(s): Investigational
Molecular Formula:: C21H29N5O2
Molecular Weight:: 383.487
Log P:: 1.3507
Hydrogen Bond Acceptor:: 7
Hydrogen Bond Donor:: 0
TPSA:: 69.64
CAS Number(s):: 87760-53-0

Synonym(s)

tandospirone

3a,4,7,7a-hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-4,7-methano-1H-isoindole-1,3(2H)-dione

SM 3997

SM-3997

External Link(s)

MeSH	C055267
PubChem Compound	91273
BindingDB	50368723 50099385
ChEBI	145673 32182
CHEMBL	CHEMBL274047
DrugBank	DB12833
DrugCentral	2563
IUPHAR/BPS Guide to PHARMACOLOGY	55
KEGG	dr:D08561
Therapeutic Target Database	D06OSM
ZINC	1545034

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abdominal discomfort		OFFSIDES
2	Activation syndrome		OFFSIDES
3	Alanine Aminotransferase Increased		OFFSIDES
4	Altered state of consciousness		OFFSIDES
5	Anorexia		OFFSIDES
6	Anuria		OFFSIDES
7	Aspiration Pneumonia		OFFSIDES
8	Bed rest		OFFSIDES
9	Blood alkaline phosphatase increased		OFFSIDES
10	Blood amylase increased		OFFSIDES
11	Blood chloride decreased		OFFSIDES
12	Blood creatine phosphokinase increased		OFFSIDES
13	Blood creatinine increased		OFFSIDES
14	Blood lactate dehydrogenase increased		OFFSIDES
15	Blood potassium decreased		OFFSIDES
16	Blood sodium increased		OFFSIDES
17	Blood uric acid		OFFSIDES
18	Catalepsy	19352073	CTD
19	Cataract		OFFSIDES
20	Cellulitis		OFFSIDES
21	Chemotherapeutic drug level increased		OFFSIDES
22	Citrobacter infection		OFFSIDES
23	Depressed Level of Consciousness		OFFSIDES
24	Depressed mood		OFFSIDES
25	Diaphragmalgia		OFFSIDES
26	Disseminated Intravascular Coagulation		OFFSIDES
27	Drowsiness		OFFSIDES
28	Drug prescribing error		OFFSIDES
29	Dyskinesia, Drug-Induced	11889759	CTD
30	Dyspareunia		OFFSIDES
31	Dyspepsia		OFFSIDES
32	Emotional disorder		OFFSIDES
33	Endometriosis		OFFSIDES
34	Epilepsy		OFFSIDES
35	Erythema Multiforme		OFFSIDES
36	Eyelid Function Disorder		OFFSIDES
37	Galactorrhea		OFFSIDES
38	Glossoptosis		OFFSIDES
39	Human herpes virus 6 serology positive		OFFSIDES
40	Hyperreflexia		OFFSIDES
41	Hyperventilation		OFFSIDES
42	Hypokinesia	18495311	CTD
43	Hypoxia		OFFSIDES
44	Impetigo		OFFSIDES
45	Infection in an immunocompromised host		OFFSIDES
46	Intention tremor		OFFSIDES
47	Leukopenia neonatal		OFFSIDES
48	Lymphocyte count decreased		OFFSIDES
49	Multiple drug overdose		OFFSIDES
50	Multiple drug overdose intentional		OFFSIDES
51	Muscle necrosis		OFFSIDES
52	Musculoskeletal stiffness		OFFSIDES
53	Nasopharyngitis		OFFSIDES
54	Neuroleptic Malignant Syndrome		OFFSIDES
55	Pain		OFFSIDES
56	Pertussis		OFFSIDES
57	Postoperative Nausea and Vomiting	12401641	CTD
58	Protein total decreased		OFFSIDES
59	Psoriasis		OFFSIDES
60	Pyoderma Gangrenosum		OFFSIDES
61	REM Sleep Behavior Disorder	17644482	CTD
62	Rhabdomyolysis		OFFSIDES
63	Scotoma		OFFSIDES
64	Sjogren's Syndrome		OFFSIDES
65	Skin Erosion		OFFSIDES
66	Skin laceration		OFFSIDES
67	Sleep Talking		OFFSIDES
68	Theft		OFFSIDES
69	Thermometry abnormal		OFFSIDES
70	Tremor	11070179	CTD
71	Vitrectomy		OFFSIDES
72	Wrong technique in drug usage process		OFFSIDES

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