MetaADEDB 2.0 @ LMMD
Mefenamic Acid
(HYYBABOKPJLUIN-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)c1ccccc1Nc1cccc(c1C)C
Type(s)
Approved
ATC code(s)
M01AG01
Molecular Formula:
C15H15NO2
Molecular Weight:
241.285
Log P:
3.8182
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
2
TPSA:
49.33
CAS Number(s):
61-68-7
Synonym(s)
1.
Mefenamic Acid
2.
Apo-Mefenamic
3.
Contraflam
4.
Coslan
5.
Dysman
6.
Mefac
7.
Mefacit
8.
Mefenaminic Acid
9.
Mefic
10.
Nu-Mefenamic
11.
PMS-Mefenamic Acid
12.
Parkemed
13.
Pinalgesic
14.
Ponalar
15.
Ponalgic
16.
Ponmel
17.
Ponstan
18.
Ponstan Forte
19.
Ponstel
20.
Ponsyl
21.
Pontal
22.
Acid, Mefenamic
23.
Apo Mefenamic
24.
Nu Mefenamic
25.
PMS Mefenamic Acid
External Link(s)
MeSHD008528
PubChem Compound4044
BindingDB50134036
ChEBI6717
CHEMBLCHEMBL686
DrugBankDB00784
DrugCentral1663
IUPHAR/BPS Guide to PHARMACOLOGY2593
KEGGcpd:C02168
dr:D00151
Therapeutic Target DatabaseD05FTJ
ZINC20241
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1VomitingFAERS: 10
Canada Vigilance: 2

View details

2314551
3140090
3928071
6783206
 		CTD
Canada Vigilance
US FAERS
2OverdoseFAERS: 8OFFSIDES
US FAERS
3Stevens-Johnson SyndromeFAERS: 425811541CTD
OFFSIDES
US FAERS
4AbasiaFAERS: 3US FAERS
5Intentional drug misuseFAERS: 3US FAERS
6NauseaFAERS: 3OFFSIDES
US FAERS
7Oculomucocutaneous syndromeFAERS: 3OFFSIDES
US FAERS
8ArthralgiaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
9AstheniaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
10ColitisFAERS: 27640566CTD
US FAERS
11Feeling abnormalFAERS: 2US FAERS
12MyalgiaFAERS: 2US FAERS
13PainFAERS: 2
Canada Vigilance: 1		6105396CTD
Canada Vigilance
US FAERS
14PruritusFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
15furuncleFAERS: 2OFFSIDES
US FAERS
16Accidental overdoseFAERS: 1US FAERS
17Adverse eventFAERS: 1US FAERS
18Anaphylactic shockFAERS: 1US FAERS
19AnorexiaFAERS: 12314551CTD
OFFSIDES
US FAERS
20AnuriaFAERS: 1OFFSIDES
US FAERS
21BedriddenFAERS: 1US FAERS
22BronchitisFAERS: 1US FAERS
23Cardiac ArrestFAERS: 1US FAERS
24Deep Vein ThrombosisFAERS: 1US FAERS
25DehydrationFAERS: 1US FAERS
26DiplegiaFAERS: 1US FAERS
27Drug ineffectiveFAERS: 1US FAERS
28Escherichia urinary tract infectionFAERS: 1OFFSIDES
US FAERS
29FatigueFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
30Guillain-Barre SyndromeFAERS: 1US FAERS
31HeadacheFAERS: 1
Canada Vigilance: 1		16504799CTD
Canada Vigilance
US FAERS
32HypersensitivityFAERS: 1US FAERS
33Ileal ulcerFAERS: 1OFFSIDES
US FAERS
34Impaired work abilityFAERS: 1US FAERS
35Inappropriate schedule of drug administrationFAERS: 1US FAERS
36Incorrect dose administeredFAERS: 1US FAERS
37Lymphocyte stimulation test positiveFAERS: 1OFFSIDES
US FAERS
38Malacoplakia vesicaeFAERS: 1US FAERS
39MalaiseFAERS: 1US FAERS
40Medication ErrorFAERS: 1US FAERS
41Musculoskeletal stiffnessFAERS: 1OFFSIDES
US FAERS
42Myocardial InfarctionFAERS: 1US FAERS
43Myoclonic EpilepsyFAERS: 1US FAERS
44NervousnessFAERS: 1US FAERS
45OligohydramniosFAERS: 1US FAERS
46Pharyngolaryngeal PainFAERS: 1OFFSIDES
US FAERS
47PoisoningFAERS: 128728110CTD
US FAERS
48Post procedural painFAERS: 1OFFSIDES
US FAERS
49Product substitution issueFAERS: 1US FAERS
50Product use in unapproved indicationFAERS: 1US FAERS
51Pulmonary HypertensionFAERS: 1US FAERS
52Respiratory arrestFAERS: 1US FAERS
53SepsisFAERS: 1US FAERS
54SomnolenceFAERS: 1US FAERS
55Sudden deathFAERS: 1US FAERS
56SwellingFAERS: 1US FAERS
57Symmetrical drug-related intertriginous and flexural exanthemaFAERS: 1US FAERS
58SyncopeFAERS: 1US FAERS
59Tubal LigationFAERS: 1US FAERS
60Ventricular FibrillationFAERS: 1US FAERS
61Ventricular FlutterFAERS: 1US FAERS
62Abdominal PainCanada Vigilance: 13140090
7640566		CTD
Canada Vigilance
63AbscessOFFSIDES
64AcidosisOFFSIDES
65Acute kidney injuryCanada Vigilance: 1

View details

1284748
2217015
2739843
3126948
3140090
3928071
3931786
4081705
6105396
6106853
6694957
6783206
7640566
7811132
19369842
 		CTD
Canada Vigilance
66AgitationCanada Vigilance: 1Canada Vigilance
67Alanine Aminotransferase IncreasedOFFSIDES
68Alcoholic IntoxicationOFFSIDES
69AlopeciaOFFSIDES
70Altered state of consciousnessOFFSIDES
71AmenorrheaOFFSIDES
72AmphetaminesOFFSIDES
73Anemia, Hemolytic3540922
5420190
8235782		CTD
74AngioedemaCanada Vigilance: 21115460CTD
Canada Vigilance
75Aphthous StomatitisOFFSIDES
76AscitesOFFSIDES
77AtaxiaOFFSIDES
78AthetosisOFFSIDES
79Autoimmune hepatitisOFFSIDES
80BalanitisOFFSIDES
81Basal Ganglia Diseases6864714CTD
82Blood alkaline phosphatase increasedOFFSIDES
83Blood chloride increasedOFFSIDES
84Blood creatinine increasedOFFSIDES
85Blood magnesium decreasedOFFSIDES
86Blood urea increasedOFFSIDES
87BronchopneumoniaOFFSIDES
88Bulbar palsyOFFSIDES
89Cardiac DeathOFFSIDES
90Cartilage injuryOFFSIDES
91CataractOFFSIDES
92CatatoniaOFFSIDES
93CellulitisOFFSIDES
94Cervical dysplasiaOFFSIDES
95CheilitisOFFSIDES
96Chemical and Drug Induced Liver Injury6942063
23152190
25372302		CTD
97Chest PainCanada Vigilance: 1Canada Vigilance
98ChillsCanada Vigilance: 2Canada Vigilance
99ChloasmaOFFSIDES
100CholangiolitisOFFSIDES
101Cogwheel RigidityOFFSIDES
102Concomitant disease aggravatedOFFSIDES
103Conjunctival Diseases1115460CTD
104Cubital Tunnel SyndromeOFFSIDES
105CystOFFSIDES
106DermatitisCanada Vigilance: 1Canada Vigilance
107Diarrhea

View details

2314551
3140090
3524092
3540922
3928071
5676955
6783206
7640566
 		CTD
OFFSIDES
108Disseminated Intravascular CoagulationOFFSIDES
109DizzinessCanada Vigilance: 2Canada Vigilance
110DrowsinessOFFSIDES
111Drug Eruptions11792017CTD
112Drug Overdose3126948
7640566		CTD
113Drug withdrawal headacheOFFSIDES
114Dysmenorrhea448996
6864714		CTD
OFFSIDES
115DyspepsiaCanada Vigilance: 1Canada Vigilance
116DysphoniaOFFSIDES
117Dysthymic DisorderOFFSIDES
118DystoniaOFFSIDES
119EczemaCanada Vigilance: 1Canada Vigilance
120Edema16504799CTD
121EndocarditisOFFSIDES
122EndometriosisOFFSIDES
123Eosinophilic PneumoniaOFFSIDES
124EpilepsyOFFSIDES
125EpistaxisOFFSIDES
126Erythema MultiformeOFFSIDES
127ErythemaCanada Vigilance: 2Canada Vigilance
128Esophageal StenosisOFFSIDES
129Euphoric moodOFFSIDES
130Febrile NeutropeniaOFFSIDES
131Fetal Diseases1930046CTD
132Fever6124751CTD
133FibromyalgiaOFFSIDES
134Fibrosis2739843CTD
135Fluid overloadOFFSIDES
136FlushingCanada Vigilance: 1Canada Vigilance
137FormicationOFFSIDES
138Gastric ulcerOFFSIDES
139GastroenteritisOFFSIDES
140Gastrointestinal Diseases25372302CTD
141Gastrointestinal inflammationOFFSIDES
142GlobulinuriaOFFSIDES
143Glomerulonephritis, Membranoproliferative3140090CTD
144GoiterOFFSIDES
145Granulomatous liver diseaseOFFSIDES
146Hematuria2240058CTD
147HemiparesisOFFSIDES
148HistoplasmosisOFFSIDES
149HyperreflexiaOFFSIDES
150HypoxiaOFFSIDES
151Iatrogenic injuryOFFSIDES
152Ideas of referenceOFFSIDES
153InfectionOFFSIDES
154Infusion site mobility decreasedOFFSIDES
155Injury asphyxiationOFFSIDES
156Kidney Diseases

View details

1783953
3375885
6942063
24552538
25372302
 		CTD
157Kidney Failure, Chronic2314551CTD
158Kidney Papillary Necrosis

View details

2240058
3126948
6105396
12512867
 		CTD
159LethargyCanada Vigilance: 1Canada Vigilance
160LeukoencephalopathyOFFSIDES
161Leukopenia neonatalOFFSIDES
162LeukopeniaCanada Vigilance: 1Canada Vigilance
163Lupus Erythematosus, Systemic6694957CTD
164LymphedemaOFFSIDES
165Mediastinal massOFFSIDES
166Menorrhagia19016686CTD
167Mental retardation severity unspecifiedOFFSIDES
168Metabolic acidosisOFFSIDES
169Migraine Disorders3524092
20726208		CTD
170MononeuritisOFFSIDES
171Multiple drug overdoseOFFSIDES
172Multiple drug overdose intentionalOFFSIDES
173Multiple sclerosis relapseOFFSIDES
174Muscle Rigidity6864714CTD
175Muscle tightnessOFFSIDES
176MyelitisOFFSIDES
177MyelodysplasiaOFFSIDES
178NasopharyngitisOFFSIDES
179Nephritis, Interstitial

View details

2739843
3126948
3140090
4081705
6106853
6694957
6784867
7811132
15651168
 		CTD
180Nephrotic Syndrome3126948CTD
181NeurosyphilisOFFSIDES
182Neutropenia2217015CTD
183Non-cardiac chest painOFFSIDES
184NystagmusOFFSIDES
185Oliguria16504799CTD
OFFSIDES
186Oropharyngeal painOFFSIDES
187OrthopneaOFFSIDES
188Pain, Postoperative4417046CTD
189PallorOFFSIDES
190Panic DisorderOFFSIDES
191Polyhydramnios1930046CTD
192PolyuriaOFFSIDES
193Post procedural discomfortOFFSIDES
194Post procedural dizzinessOFFSIDES
195Postoperative infectionOFFSIDES
196Proteinuria2314551CTD
197Pulmonary InfarctionOFFSIDES
198PurpuraCanada Vigilance: 1Canada Vigilance
199Renal tubular necrosisOFFSIDES
200Respiratory FailureOFFSIDES
201Risus sardonicusOFFSIDES
202Salpingitis6124751CTD
203Sciatica6106853CTD
204Seizures

View details

3191389
6115180
6433367
7824546
16504799
 		CTD
205Serum SicknessCanada Vigilance: 1Canada Vigilance
206ShockCanada Vigilance: 1Canada Vigilance
207Sinus polypOFFSIDES
208SinusitisOFFSIDES
209Spasm6864714CTD
210Steatorrhea3928071CTD
211Subcutaneous AbscessOFFSIDES
212Supraventricular tachycardiaOFFSIDES
213Therapy non-responderOFFSIDES
214Thrombocytopenia1284748CTD
215Tinnitus18632935CTD
216Torticollis6864714CTD
217UrticariaCanada Vigilance: 11115460
11792017		CTD
Canada Vigilance
218Uterine spasmOFFSIDES
219Venous Thromboembolism19016686CTD
220Vocal cord cystOFFSIDES
221Weight decrease neonatalOFFSIDES
222jaundice1284748CTD
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