MetaADEDB 2.0 @ LMMD
Atomoxetine Hydrochloride
(VHGCDTVCOLNTBX-QGZVFWFLSA-N)
Structure
SMILES
CNCC[C@H](c1ccccc1)Oc1ccccc1C
Type(s)
Approved
ATC code(s)
N06BA09
Molecular Formula:
C17H21NO
Molecular Weight:
255.355
Log P:
4.1155
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
21.26
CAS Number(s):
83015-26-3
Synonym(s)
1.
Atomoxetine Hydrochloride
2.
Atomoxetine
3.
Atomoxetine HCl
4.
LY 139603
5.
N-methyl-gamma-(2-methylphenoxy)benzenepropanamine hydrochloride
6.
Strattera
7.
Tomoxetine
8.
Tomoxetine Hydrochloride, (+)-isomer - T351671
9.
Tomoxetine Hydrochloride, (+-)-isomer
10.
Tomoxetine Hydrochloride, (-)-isomer
11.
139603, LY
12.
HCl, Atomoxetine
13.
Hydrochloride, Atomoxetine
External Link(s)
MeSHD000069445
PubChem Compound54841
BindingDB50366567
ChEBI127342
CHEMBLCHEMBL641
DrugBankDB00289
DrugCentral256
IUPHAR/BPS Guide to PHARMACOLOGY7118
KEGGdr:D07473
Therapeutic Target DatabaseD04CRN
ZINC1842633
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Product substitution issueFAERS: 37
Canada Vigilance: 4
Canada Vigilance
US FAERS
2Drug ineffectiveFAERS: 19
Canada Vigilance: 9
Canada Vigilance
OFFSIDES
US FAERS
3AngerFAERS: 10
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
4AnxietyFAERS: 9
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
5AgitationFAERS: 5
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
6FatigueFAERS: 5
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
7HeadacheFAERS: 5
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
8NervousnessFAERS: 5SIDER
US FAERS
9Abdominal discomfortFAERS: 4OFFSIDES
SIDER
US FAERS
10Erectile dysfunctionFAERS: 4
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
11Feeling abnormalFAERS: 4OFFSIDES
SIDER
US FAERS
12Frustration tolerance decreasedFAERS: 4US FAERS
13NauseaFAERS: 4
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
14SomnolenceFAERS: 4
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
15TremorFAERS: 4SIDER
US FAERS
16ChromaturiaFAERS: 3
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
17Abdominal PainFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
18AstheniaFAERS: 2OFFSIDES
SIDER
US FAERS
19CamptocormiaFAERS: 2US FAERS
20Chest PainFAERS: 2SIDER
US FAERS
21CholecystitisFAERS: 2US FAERS
22Depressed moodFAERS: 2SIDER
US FAERS
23Disturbance in sexual arousalFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
24DysuriaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
25Educational problemFAERS: 2OFFSIDES
US FAERS
26LeukopeniaFAERS: 2US FAERS
27MalaiseFAERS: 2US FAERS
28Memory impairmentFAERS: 2US FAERS
29Mood swingsFAERS: 2SIDER
US FAERS
30Nipple painFAERS: 2OFFSIDES
US FAERS
31Painful ejaculationFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
32Sleep ParalysisFAERS: 2OFFSIDES
US FAERS
33Spermatozoa abnormalFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
34Therapeutic product effect decreasedFAERS: 2US FAERS
35Therapy non-responderFAERS: 2US FAERS
36VomitingFAERS: 2
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
37ApathyFAERS: 1OFFSIDES
US FAERS
38AphasiaFAERS: 1US FAERS
39Breast tendernessFAERS: 1US FAERS
40Cardiac FlutterFAERS: 1US FAERS
41CardiomegalyFAERS: 1US FAERS
42Chest discomfortFAERS: 1US FAERS
43ChokingFAERS: 1OFFSIDES
US FAERS
44CryingFAERS: 1OFFSIDES
SIDER
US FAERS
45Disease recurrenceFAERS: 1US FAERS
46DisorientationFAERS: 1SIDER
US FAERS
47DizzinessFAERS: 1OFFSIDES
SIDER
US FAERS
48Drug DependenceFAERS: 1SIDER
US FAERS
49Drug effect delayedFAERS: 1US FAERS
50Drug ineffective for unapproved indicationFAERS: 1US FAERS
51Drug screen false positiveFAERS: 1US FAERS
52DyspepsiaFAERS: 1OFFSIDES
SIDER
US FAERS
53DysphemiaFAERS: 1US FAERS
54DystoniaFAERS: 1US FAERS
55Emotional disorderFAERS: 1OFFSIDES
US FAERS
56Emotional distressFAERS: 1OFFSIDES
US FAERS
57ErythemaFAERS: 1OFFSIDES
US FAERS
58Excessive eye blinkingFAERS: 1US FAERS
59Genital dischargeFAERS: 1OFFSIDES
US FAERS
60HemiparesisFAERS: 1US FAERS
61HypersensitivityFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
62Impaired work abilityFAERS: 1US FAERS
63InflammationFAERS: 1US FAERS
64Insurance issueFAERS: 1US FAERS
65Irritable Bowel SyndromeFAERS: 1US FAERS
66Long QT SyndromeFAERS: 1US FAERS
67Loss of personal independence in daily activitiesFAERS: 1US FAERS
68Male Orgasmic DisorderFAERS: 1OFFSIDES
US FAERS
69Mental impairmentFAERS: 1US FAERS
70Negative thoughtsFAERS: 1US FAERS
71PalpitationsFAERS: 1SIDER
US FAERS
72Personality ChangeFAERS: 1OFFSIDES
US FAERS
73Poor quality sleepFAERS: 1US FAERS
74Premature EjaculationFAERS: 1US FAERS
75Product monitoring errorFAERS: 1US FAERS
76Product physical issueFAERS: 1US FAERS
77Product quality issueFAERS: 1US FAERS
78Product size issueFAERS: 1US FAERS
79Product taste abnormalFAERS: 1US FAERS
80RestlessnessFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
81ScreamingFAERS: 1OFFSIDES
US FAERS
82Sinus bradycardiaFAERS: 1US FAERS
83StressFAERS: 1US FAERS
84SyncopeFAERS: 1SIDER
US FAERS
85TachycardiaFAERS: 1SIDER
US FAERS
86Therapeutic product effect incompleteFAERS: 1US FAERS
87Therapy cessationFAERS: 1US FAERS
88Unevaluable eventFAERS: 1US FAERS
89Unresponsive to stimuliFAERS: 1US FAERS
90Urinary IncontinenceFAERS: 1US FAERS
91Urinary hesitationFAERS: 1SIDER
US FAERS
92Weight decreasedFAERS: 1SIDER
US FAERS
93skin abrasionFAERS: 1US FAERS
94Abdominal massOFFSIDES
95Abdominal rebound tendernessOFFSIDES
96Abnormal sleep-related eventOFFSIDES
97Accidental deathOFFSIDES
98Accidental drug intake by childOFFSIDES
99Accidental overdoseOFFSIDES
100AcholiaOFFSIDES
101Acid refluxOFFSIDES
102Acute Coronary SyndromeOFFSIDES
103Acute bronchitisOFFSIDES
104AdenoidectomyOFFSIDES
105AdenomaOFFSIDES
106AgoraphobiaOFFSIDES
107Alanine Aminotransferase IncreasedOFFSIDES
108Alanine aminotransferase abnormalOFFSIDES
109Alcohol abuseOFFSIDES
110Alcohol consumptionOFFSIDES
111Alcohol interactionOFFSIDES
112Alpha 2 globulin increasedOFFSIDES
113Alpha-1 anti-trypsin increasedOFFSIDES
114Altered bowel functionOFFSIDES
115AlveolitisOFFSIDES
116Amphetamines positiveOFFSIDES
117AnencephalyOFFSIDES
118AnorexiaOFFSIDES
SIDER
119Anticholinergic SyndromeOFFSIDES
120AppendicitisOFFSIDES
121ArteriosclerosisOFFSIDES
122ArthralgiaSIDER
123ArthroscopyOFFSIDES
124Aspartate aminotransferase abnormalOFFSIDES
125AsterixisOFFSIDES
126AsthenopiaOFFSIDES
127Atrial FlutterOFFSIDES
128Atrioventricular BlockOFFSIDES
129Atypical benign partial epilepsyOFFSIDES
130Autoimmune hepatitisOFFSIDES
131Autonomic nervous system imbalanceSIDER
132Back PainSIDER
133Band neutrophil count increasedOFFSIDES
134Band neutrophil percentage decreasedOFFSIDES
135Beckwith-Wiedemann SyndromeOFFSIDES
136BelligerenceOFFSIDES
137Benign Prostatic HyperplasiaOFFSIDES
138Bilirubin conjugated increasedOFFSIDES
139Biopsy liver abnormalOFFSIDES
140Bladder spasmOFFSIDES
141BlepharospasmOFFSIDES
142Blood GlucoseOFFSIDES
143Blood albumin increasedOFFSIDES
144Blood alkaline phosphatase abnormalOFFSIDES
145Blood alkaline phosphatase decreasedOFFSIDES
146Blood alkaline phosphatase increasedOFFSIDES
147Blood amino acid level increasedOFFSIDES
148Blood amylase increasedOFFSIDES
149Blood bilirubin abnormalOFFSIDES
150Blood bilirubin unconjugated increasedOFFSIDES
151Blood catecholamines increasedOFFSIDES
152Blood corticotrophin increasedOFFSIDES
153Blood cortisol decreasedOFFSIDES
154Blood count abnormalOFFSIDES
155Blood creatine increasedOFFSIDES
156Blood creatinine decreasedOFFSIDES
157Blood galactose increasedOFFSIDES
158Blood glucose decreasedOFFSIDES
159Blood glucose fluctuationOFFSIDES
160Blood immunoglobulin EOFFSIDES
161Blood immunoglobulin G increasedOFFSIDES
162Blood iron decreasedOFFSIDES
163Blood iron increasedOFFSIDES
164Blood ketone body increasedOFFSIDES
165Blood magnesium increasedOFFSIDES
166Blood phosphorus decreasedOFFSIDES
167Blood sodium increasedOFFSIDES
168Blood testosterone increasedOFFSIDES
169Blood urine presentOFFSIDES
170Bone marrow depressionOFFSIDES
171BoredomOFFSIDES
172Brain DeathOFFSIDES
173Buccoglossal syndromeOFFSIDES
174BulimiaOFFSIDES
175CarditisOFFSIDES
176Carnitine increasedOFFSIDES
177Ceruloplasmin increasedOFFSIDES
178ChillsSIDER
179CholangiolitisOFFSIDES
180Cholestatic liver injuryOFFSIDES
181Chronic active hepatitisOFFSIDES
182Circumstance or information capable of leading to medication errorOFFSIDES
183CirrhosisOFFSIDES
184Cleft PalateOFFSIDES
185Coagulation time shortenedOFFSIDES
186Cold sweatOFFSIDES
187Completed SuicideSIDER
188Complex partial seizuresOFFSIDES
189Congenital hypertrichosisOFFSIDES
190ConjunctivitisSIDER
191Consciousness fluctuatingOFFSIDES
192ConstipationSIDER
193Croup infectiousOFFSIDES
194Cytomegalovirus antibody positiveOFFSIDES
195Dark circles under eyesOFFSIDES
196Decreased LibidoOFFSIDES
197Decreased immune responsivenessOFFSIDES
198DeliriumSIDER
199Delusional disorder, persecutory typeOFFSIDES
200DependenceSIDER
201Dependent Personality DisorderOFFSIDES
202DermatitisSIDER
203Dissociative disorderOFFSIDES
204Dopamine dysregulation syndromeOFFSIDES
205DrowningOFFSIDES
206DrowsinessOFFSIDES
207Drug abuseSIDER
208Drug screen positiveOFFSIDES
209Drug withdrawal convulsionsOFFSIDES
210Drug withdrawal headacheOFFSIDES
211DuodenitisOFFSIDES
212DysacusisOFFSIDES
213DysgeusiaOFFSIDES
SIDER
214DysgraphiaOFFSIDES
215Dysthymic DisorderOFFSIDES
216Electrocardiogram ST segment abnormalOFFSIDES
217Electrocardiogram changeOFFSIDES
218Elevated moodOFFSIDES
219Endodontic procedureOFFSIDES
220Endometrial HyperplasiaOFFSIDES
221EndometriosisOFFSIDES
222EnterobiasisOFFSIDES
223EnuresisOFFSIDES
224Enzyme abnormalityOFFSIDES
225Eosinophilic myocarditisOFFSIDES
226EpididymitisOFFSIDES
227Epigastric discomfortSIDER
228EpiglottitisOFFSIDES
229EpilepsyOFFSIDES
230EpistaxisOFFSIDES
231Epstein-Barr virus antibody positiveOFFSIDES
232Erection increasedSIDER
233Erection prolongedSIDER
234Escherichia infectionOFFSIDES
235Esophageal PerforationOFFSIDES
236ExcoriationOFFSIDES
SIDER
237Exposure to toxic agentOFFSIDES
238Eye RednessOFFSIDES
239Eye painOFFSIDES
240Fatty LiverOFFSIDES
241Feeling ColdOFFSIDES
242Feeling jitterySIDER
243Female sexual dysfunctionSIDER
244Flank PainOFFSIDES
245Flat affectOFFSIDES
246FlatulenceOFFSIDES
SIDER
247FlushingSIDER
248Food PoisoningOFFSIDES
249Food aversionOFFSIDES
250Forceps deliveryOFFSIDES
251FormicationOFFSIDES
252GamblingOFFSIDES
253Gamma-Glutamyltransferase IncreasedOFFSIDES
254GastroenteritisOFFSIDES
255Gastrointestinal PainSIDER
256Genital infection fungalOFFSIDES
257Genital painOFFSIDES
SIDER
258Gingival HyperplasiaOFFSIDES
259Granulocyte count decreasedOFFSIDES
260Hay feverOFFSIDES
261Hepatic InsufficiencySIDER
262Hepatic necrosisOFFSIDES
263Hepatitis B positiveOFFSIDES
264Hepatitis B surface antigen positiveOFFSIDES
265Hepatitis C positiveOFFSIDES
266HepatitisOFFSIDES
267HepatosplenomegalyOFFSIDES
268HepatotoxicityOFFSIDES
269HoarsenessOFFSIDES
270HomicideOFFSIDES
271HostilitySIDER
272Human BiteOFFSIDES
273HyperventilationOFFSIDES
274Hypocoagulable stateOFFSIDES
275Ideas of referenceOFFSIDES
276Idiosyncratic drug reactionOFFSIDES
277Ileal StenosisOFFSIDES
278IncontinenceOFFSIDES
279InfectionOFFSIDES
SIDER
280InfestationSIDER
281InfluenzaSIDER
282Initial insomniaOFFSIDES
SIDER
283Injury asphyxiationOFFSIDES
284Insulin-like growth factor decreasedOFFSIDES
285Intentional misuseOFFSIDES
286Intentional self-injuryOFFSIDES
287Intervertebral disc compressionOFFSIDES
288IridoceleOFFSIDES
289Iron binding capacity unsaturated decreasedOFFSIDES
290Joint sprainOFFSIDES
291Keratitis siccaOFFSIDES
292LacerationOFFSIDES
293LazinessOFFSIDES
294LethargyOFFSIDES
SIDER
295LeukoencephalopathyOFFSIDES
296Ligament ruptureOFFSIDES
297Liver indurationOFFSIDES
298Liver palpable subcostalOFFSIDES
299Lower respiratory tract infection viralOFFSIDES
300Lung infection pseudomonalOFFSIDES
301Lupus-like syndromeOFFSIDES
302Male sexual dysfunctionOFFSIDES
303MalnutritionSIDER
304Markedly reduced dietary intakeOFFSIDES
305Mental status changesSIDER
306Metanephrine urine increasedOFFSIDES
307Micturition frequency decreasedOFFSIDES
308Middle insomniaOFFSIDES
SIDER
309Milk AllergyOFFSIDES
310MonocytosisOFFSIDES
311Mononucleosis heterophile test positiveOFFSIDES
312Mononucleosis syndromeOFFSIDES
313Morbid thoughtsCanada Vigilance: 1Canada Vigilance
OFFSIDES
314Motion SicknessOFFSIDES
315Multiple allergiesOFFSIDES
316Multiple drug overdoseOFFSIDES
317Multiple drug overdose intentionalOFFSIDES
318Muscle RigiditySIDER
319Muscular DystrophyOFFSIDES
320Musculoskeletal discomfortSIDER
321MyalgiaSIDER
322MydriasisSIDER
323MyelitisOFFSIDES
324Myoclonic EpilepsyOFFSIDES
325MyoclonusSIDER
326Nail pigmentationOFFSIDES
327Nasal discomfortOFFSIDES
328NasopharyngitisOFFSIDES
SIDER
329NegativismOFFSIDES
330Nervous tensionOFFSIDES
331NeurodermatitisOFFSIDES
332Neuroleptic Malignant SyndromeSIDER
333Neuromyelitis OpticaOFFSIDES
334NocturiaOFFSIDES
335Nodule on extremityOFFSIDES
336Norepinephrine increasedOFFSIDES
337Normetanephrine urine increasedOFFSIDES
338Ocular icterusOFFSIDES
339OculogyrationOFFSIDES
340OligomenorrheaOFFSIDES
341OliguriaOFFSIDES
342OpisthotonusOFFSIDES
343Oppositional Defiant DisorderOFFSIDES
344Optic AtrophyOFFSIDES
345Optic NeuritisOFFSIDES
346Oral dischargeOFFSIDES
347Oral mucosal petechiaeOFFSIDES
348Orgasmic sensation decreasedOFFSIDES
349Oropharyngeal discomfortSIDER
350Oropharyngeal painSIDER
351Oropharyngeal swellingOFFSIDES
352Orthostatic intoleranceOFFSIDES
353OverweightOFFSIDES
354PainSIDER
355PallorOFFSIDES
356Pancreatitis viralOFFSIDES
357Paranasal sinus hypersecretionOFFSIDES
358ParotitisOFFSIDES
359Pelvic PainSIDER
360Penile blisterOFFSIDES
361Penile size reducedOFFSIDES
362Performance status decreasedOFFSIDES
363PeritonitisOFFSIDES
364Perivascular dermatitisOFFSIDES
365Pharyngolaryngeal PainOFFSIDES
SIDER
366PiloerectionOFFSIDES
367Platelet function test abnormalOFFSIDES
368PolymyositisOFFSIDES
369Precocious PubertyOFFSIDES
370Prescribed overdoseOFFSIDES
371PresyncopeSIDER
372Product used for unknown indicationCanada Vigilance: 1Canada Vigilance
373Protein total increasedOFFSIDES
374PruritusSIDER
375Psychiatric investigationOFFSIDES
376Pyloric StenosisOFFSIDES
377Quality of life decreasedOFFSIDES
378Red man syndromeOFFSIDES
379Refusal of examinationOFFSIDES
380RegurgitationOFFSIDES
381Renin increasedOFFSIDES
382Residual urineOFFSIDES
383Respiratory tract congestionOFFSIDES
384Retrograde ejaculationOFFSIDES
385RhinorrheaOFFSIDES
386Ruptured cerebral aneurysmOFFSIDES
387School refusalOFFSIDES
388Semen abnormalOFFSIDES
389Semen viscosityOFFSIDES
390Semen volume decreasedOFFSIDES
391SemenuriaOFFSIDES
392Sexual DysfunctionSIDER
393Sexual abuseOFFSIDES
394Sexual activity increasedOFFSIDES
395Sexual inhibitionOFFSIDES
396ShockSIDER
397Sinus TachycardiaSIDER
398Sinus headacheSIDER
399SinusitisSIDER
400Sleep TalkingOFFSIDES
401Spermatozoa progressive motility decreasedOFFSIDES
402Spleen palpableOFFSIDES
403Spontaneous penile erectionOFFSIDES
404StaringOFFSIDES
405Stool analysis abnormalOFFSIDES
406StridorOFFSIDES
407Subcutaneous AbscessOFFSIDES
408Subcutaneous noduleOFFSIDES
409Suicide attemptSIDER
410Supraventricular tachycardiaOFFSIDES
411Tension HeadacheOFFSIDES
412TensionSIDER
413Testicular massOFFSIDES
414Therapeutic response unexpectedSIDER
415ThirstSIDER
416ThyroiditisOFFSIDES
417Tobacco userOFFSIDES
418TonsillectomyOFFSIDES
419Toxicologic test abnormalOFFSIDES
420TracheobronchitisOFFSIDES
421Transmission of drug via semenOFFSIDES
422TrichorrhexisOFFSIDES
423Unresponsive to pain stimuliOFFSIDES
424Upset stomachSIDER
425Urethral StenosisOFFSIDES
426Urethral dischargeOFFSIDES
427Urinary RetentionSIDER
428Urine amphetamine positiveOFFSIDES
429Urine bilirubin increasedOFFSIDES
430Urine calcium increasedOFFSIDES
431Urine flow decreasedOFFSIDES
SIDER
432Urine protein, quantitativeOFFSIDES
433Urobilin urine presentOFFSIDES
434UrticariaSIDER
435Vagus Nerve DisorderOFFSIDES
436VertigoSIDER
437Viral myocarditisOFFSIDES
438Visual disturbanceOFFSIDES
439Vitamin A DeficiencyOFFSIDES
440Vulvovaginal drynessCanada Vigilance: 1Canada Vigilance
441Weight GainOFFSIDES
442YawningOFFSIDES
443nervous system disorderSIDER
444prostatitisOFFSIDES
SIDER
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