MetaADEDB 2.0 @ LMMD
Tolterodine Tartrate
(OOGJQPCLVADCPB-HXUWFJFHSA-N)
Structure
SMILES
Cc1ccc(c(c1)[C@@H](c1ccccc1)CCN(C(C)C)C(C)C)O
Type(s)
Approved; Investigational
ATC code(s)
G04BD07
Molecular Formula:
C22H31NO
Molecular Weight:
325.488
Log P:
5.3414
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
1
TPSA:
23.47
CAS Number(s):
124937-51-5; 124937-52-6
Synonym(s)
1.
Tolterodine Tartrate
2.
Detrol
3.
Detrol LA
4.
Detrusitol
5.
PHA-686464B
6.
Tolterodine
7.
Unidet
8.
Urotrol
9.
PHA 686464B
10.
PHA686464B
11.
Tartrate, Tolterodine
External Link(s)
MeSHD000068737
PubChem Compound443879
BindingDB50165008
ChEBI9622
CHEMBLCHEMBL1382
DrugBankDB01036
DrugCentral2705
IUPHAR/BPS Guide to PHARMACOLOGY360
KEGGcpd:C07750
dr:D00646
Therapeutic Target DatabaseD0BZ7W
ZINC968336
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 12
Canada Vigilance: 4		Canada Vigilance
OFFSIDES
US FAERS
2DizzinessFAERS: 8OFFSIDES
SIDER
US FAERS
3HeadacheFAERS: 5SIDER
US FAERS
4NauseaFAERS: 5US FAERS
5DysuriaFAERS: 4OFFSIDES
SIDER
US FAERS
6GastritisFAERS: 4US FAERS
7TachycardiaFAERS: 4SIDER
US FAERS
8Urinary RetentionFAERS: 4
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
9ConstipationFAERS: 3SIDER
US FAERS
10DementiaFAERS: 3SIDER
US FAERS
11FatigueFAERS: 3OFFSIDES
SIDER
US FAERS
12Lip swellingFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
13Urinary tract infectionFAERS: 3SIDER
US FAERS
14Atrial FibrillationFAERS: 2US FAERS
15Cerebrovascular accidentFAERS: 2US FAERS
16DisorientationFAERS: 2SIDER
US FAERS
17Drug effect incompleteFAERS: 2US FAERS
18IleusFAERS: 2US FAERS
19IncontinenceFAERS: 2OFFSIDES
US FAERS
20NocturiaFAERS: 2
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
21PainFAERS: 2OFFSIDES
SIDER
US FAERS
22PalpitationsFAERS: 2SIDER
US FAERS
23Product quality issueFAERS: 2US FAERS
24Product use in unapproved indicationFAERS: 2US FAERS
25Product use issueFAERS: 2US FAERS
26VomitingFAERS: 2US FAERS
27Abdominal PainFAERS: 1SIDER
US FAERS
28Abdominal discomfortFAERS: 1US FAERS
29AcidosisFAERS: 1US FAERS
30Altered state of consciousnessFAERS: 1US FAERS
31Angina PectorisFAERS: 1US FAERS
32AngioedemaFAERS: 1SIDER
US FAERS
33ArthralgiaFAERS: 1SIDER
US FAERS
34Back PainFAERS: 1US FAERS
35BlindnessFAERS: 1US FAERS
36Blood lactate dehydrogenase increasedFAERS: 1US FAERS
37BradyphreniaFAERS: 1US FAERS
38Burning sensationFAERS: 1US FAERS
39CataractFAERS: 1US FAERS
40CystitisFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
41DeafnessFAERS: 1OFFSIDES
US FAERS
42DeliriumFAERS: 1US FAERS
43Depressed Level of ConsciousnessFAERS: 1US FAERS
44Depressed moodFAERS: 1OFFSIDES
US FAERS
45Detachment of retinal pigment epitheliumFAERS: 1US FAERS
46Diabetes MellitusFAERS: 1US FAERS
47DiscomfortFAERS: 1US FAERS
48Disseminated Intravascular CoagulationFAERS: 1US FAERS
49Drug ineffective for unapproved indicationFAERS: 1US FAERS
50DysgraphiaFAERS: 1US FAERS
51ErythemaFAERS: 1OFFSIDES
US FAERS
52Eye painFAERS: 1US FAERS
53Feeling abnormalFAERS: 1OFFSIDES
SIDER
US FAERS
54FlatulenceFAERS: 1SIDER
US FAERS
55FlushingFAERS: 1SIDER
US FAERS
56Gait inabilityFAERS: 1US FAERS
57General physical health deteriorationFAERS: 1US FAERS
58HepatomegalyFAERS: 1US FAERS
59Intentional product use issueFAERS: 1US FAERS
60Joint injuryFAERS: 1OFFSIDES
US FAERS
61Limb asymmetryFAERS: 1US FAERS
62Lower Urinary Tract SymptomsFAERS: 1US FAERS
63MalaiseFAERS: 1US FAERS
64Maternal exposure during pregnancyFAERS: 1US FAERS
65Memory impairmentFAERS: 1SIDER
US FAERS
66Mental status changesFAERS: 1OFFSIDES
US FAERS
67Metastatic NeoplasmFAERS: 1US FAERS
68Mood swingsFAERS: 1US FAERS
69Morbid thoughtsFAERS: 1US FAERS
70Musculoskeletal PainFAERS: 1OFFSIDES
US FAERS
71MyalgiaFAERS: 1US FAERS
72Myocardial InfarctionFAERS: 1US FAERS
73Negative thoughtsFAERS: 1US FAERS
74NephritisFAERS: 1US FAERS
75OligohydramniosFAERS: 1US FAERS
76ParaplegiaFAERS: 1US FAERS
77ParesisFAERS: 1US FAERS
78Peripheral swellingFAERS: 1US FAERS
79Pneumatosis intestinalisFAERS: 1US FAERS
80PoisoningFAERS: 1US FAERS
81PresyncopeFAERS: 1US FAERS
82Product physical issueFAERS: 1US FAERS
83Product use complaintFAERS: 1US FAERS
84Pulmonary EmbolismFAERS: 1US FAERS
85Renal massFAERS: 1US FAERS
86Respiratory arrestFAERS: 1US FAERS
87SomnolenceFAERS: 1SIDER
US FAERS
88SyncopeFAERS: 1US FAERS
89Therapy non-responderFAERS: 1US FAERS
90ThrombosisFAERS: 1US FAERS
91ToothacheFAERS: 1US FAERS
92TremorFAERS: 1US FAERS
93UlcerFAERS: 1US FAERS
94UrticariaFAERS: 1US FAERS
95Uterine ProlapseFAERS: 1US FAERS
96Vulvovaginal discomfortFAERS: 1US FAERS
97Wrong doseFAERS: 1US FAERS
98Wrong technique in product usage processFAERS: 1US FAERS
99Abdominal massOFFSIDES
100Abnormal visionSIDER
101Acid refluxOFFSIDES
102Activated partial thromboplastin time abnormalOFFSIDES
103Acute myocardial infarctionOFFSIDES
104Acute respiratory failureOFFSIDES
105Adjustment disorder with depressed moodOFFSIDES
106Anal FissureOFFSIDES
107Anaphylactic shockSIDER
108Anaphylactoid ReactionSIDER
109AnhedoniaOFFSIDES
110Ankle FractureOFFSIDES
111Anticonvulsant drug level below therapeuticOFFSIDES
112AnuriaOFFSIDES
113AnxietyOFFSIDES
SIDER
114Aortic valve sclerosisOFFSIDES
115ApathyOFFSIDES
116AphoniaOFFSIDES
117AppendicitisOFFSIDES
118Arterial InjuryOFFSIDES
119ArteriosclerosisOFFSIDES
120ArthritisOFFSIDES
121ArthropathyOFFSIDES
122Aspiration PneumoniaOFFSIDES
123AstheniaOFFSIDES
SIDER
124AtelectasisOFFSIDES
125AuraOFFSIDES
126Autoimmune hepatitisOFFSIDES
127BK virus infectionOFFSIDES
128Basal cell carcinomaOFFSIDES
129BedriddenOFFSIDES
130BereavementOFFSIDES
131Bile duct stent insertionOFFSIDES
132Biliary DyskinesiaOFFSIDES
133BiopsyOFFSIDES
134Bladder cancer recurrentOFFSIDES
135Bladder painCanada Vigilance: 1Canada Vigilance
136Bladder spasmOFFSIDES
137Blood 1,25-dihydroxycholecalciferol decreasedOFFSIDES
138Blood GlucoseOFFSIDES
139Blood cholesterolOFFSIDES
140Blood creatinine increasedOFFSIDES
141Blood potassium decreasedOFFSIDES
142Blood triglycerides increasedOFFSIDES
143Blood urine presentOFFSIDES
144Blurred visionOFFSIDES
145Bone marrow toxicityOFFSIDES
146Bone scan abnormalOFFSIDES
147Breast CystOFFSIDES
148Breast MicrocalcificationOFFSIDES
149BronchitisSIDER
150BruxismOFFSIDES
151Capillary Leak SyndromeOFFSIDES
152Catheter placementOFFSIDES
153CellulitisOFFSIDES
154Central line infectionOFFSIDES
155Cerebellar infarctionOFFSIDES
156Cerebral atrophyOFFSIDES
157Chest PainOFFSIDES
SIDER
158ChokingOFFSIDES
159Chronic Obstructive Airway DiseaseOFFSIDES
160Chronic active hepatitisOFFSIDES
161Chronic ulcerative colitisOFFSIDES
162Circumstance or information capable of leading to medication errorOFFSIDES
163ClaustrophobiaOFFSIDES
164Clostridium difficile colitisOFFSIDES
165ColitisOFFSIDES
166Compulsive shoppingOFFSIDES
167ConfabulationOFFSIDES
168DebridementOFFSIDES
169DehydrationOFFSIDES
170DemyelinationOFFSIDES
171Dental abscessOFFSIDES
172DependenceOFFSIDES
173Device related infectionOFFSIDES
174DiabetesOFFSIDES
175Diastolic dysfunctionOFFSIDES
176Disease recurrenceOFFSIDES
177DiverticulumOFFSIDES
178Drug delivery system malfunctionOFFSIDES
179Drug withdrawal headacheOFFSIDES
180Dry skinSIDER
181DysgeusiaOFFSIDES
182DyspepsiaSIDER
183Economic problemOFFSIDES
184Electrocardiogram poor R-wave progressionOFFSIDES
185Emergency CareOFFSIDES
186Emotional distressOFFSIDES
187EpicondylitisOFFSIDES
188EpistaxisOFFSIDES
189ErythromelalgiaOFFSIDES
190ExcoriationOFFSIDES
191Eye InfectionOFFSIDES
192Eye irritationCanada Vigilance: 1Canada Vigilance
193Failure to ThriveOFFSIDES
194Fatty LiverOFFSIDES
195Feeling ColdOFFSIDES
196Flank PainOFFSIDES
197Foreign body aspirationOFFSIDES
198FormicationOFFSIDES
199GamblingOFFSIDES
200GangreneOFFSIDES
201GastroenteritisOFFSIDES
202Gastrointestinal PainSIDER
203Gastrointestinal sounds abnormalOFFSIDES
204GoutOFFSIDES
205GranulocytosisOFFSIDES
206Grip strengthOFFSIDES
207HemiparesisOFFSIDES
208HerniaOFFSIDES
209HydronephrosisOFFSIDES
210HypersensitivitySIDER
211Hypertensive cardiomyopathyOFFSIDES
212Hypertensive heart diseaseOFFSIDES
213HypoxiaOFFSIDES
214Impaired driving abilityOFFSIDES
215Impaired work abilityOFFSIDES
216Implantable defibrillator insertionOFFSIDES
217Incision site complicationOFFSIDES
218InfectionSIDER
219Influenza-like symptomsSIDER
220Insulin ResistanceOFFSIDES
221Intention tremorOFFSIDES
222Intervertebral Disc DegenerationOFFSIDES
223Intervertebral disc disorderOFFSIDES
224Intestinal ObstructionOFFSIDES
225Intrinsic factor antibody negativeOFFSIDES
226Joint sprainOFFSIDES
227LaryngospasmOFFSIDES
228LethargyOFFSIDES
229Limb discomfortOFFSIDES
230Limb injuryOFFSIDES
231Malignant neoplasm progressionOFFSIDES
232Mastication disorderOFFSIDES
233MastoiditisOFFSIDES
234Medical device complicationOFFSIDES
235Medical device implantationOFFSIDES
236MeningiomaOFFSIDES
237Metabolic acidosisOFFSIDES
238MetaplasiaOFFSIDES
239Multiple SclerosisOFFSIDES
240Multiple sclerosis relapseOFFSIDES
241Muscle WeaknessOFFSIDES
242Muscle necrosisOFFSIDES
243Musculoskeletal discomfortOFFSIDES
SIDER
244MyelodysplasiaOFFSIDES
245NephrolithiasisOFFSIDES
246OliguriaOFFSIDES
247Open reduction of fractureOFFSIDES
248Optic NeuritisOFFSIDES
249OrthopneaOFFSIDES
250OsteomyelitisOFFSIDES
251OsteoporosisOFFSIDES
252OverweightOFFSIDES
253Palmar erythemaOFFSIDES
254PancreatitisOFFSIDES
255Paranasal sinus hypersecretionOFFSIDES
256Penile erythemaCanada Vigilance: 1Canada Vigilance
257PneumothoraxOFFSIDES
258Polymyalgia RheumaticaOFFSIDES
259Post procedural complicationOFFSIDES
260Postoperative wound complicationOFFSIDES
261Product substitution issueCanada Vigilance: 5Canada Vigilance
262Productive CoughOFFSIDES
263Progressive supranuclear palsyOFFSIDES
264Protein total increasedOFFSIDES
265Refusal of treatment by relativeOFFSIDES
266Renal cystOFFSIDES
267Respiratory FailureOFFSIDES
268SclerodermaOFFSIDES
269SinusitisOFFSIDES
SIDER
270Skin lacerationOFFSIDES
271Spinal column stenosisOFFSIDES
272StaringOFFSIDES
273Stent occlusionOFFSIDES
274Submandibular massOFFSIDES
275Synovial CystOFFSIDES
276SyphilisOFFSIDES
277Terminal dribblingOFFSIDES
278Tooth ExtractionOFFSIDES
279Tooth InfectionOFFSIDES
280Unresponsive to stimuliOFFSIDES
281Urge IncontinenceOFFSIDES
282Ventricular FibrillationOFFSIDES
283VertigoSIDER
284Visual ImpairmentSIDER
285Vitamin B 12 DeficiencyOFFSIDES
286Vitamin B12 abnormalOFFSIDES
287Vulvovaginal drynessOFFSIDES
288Vulvovaginal mycotic infectionOFFSIDES
289Weight GainOFFSIDES
290Wheelchair userOFFSIDES
291Wound InfectionOFFSIDES
292XerophthalmiaSIDER
293colonoscopyOFFSIDES
294effusionOFFSIDES
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