MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Temazepam

(SEQDDYPDSLOBDC-UHFFFAOYSA-N)

Structure

SMILES: Clc1ccc2c(c1)C(=NC(C(=O)N2C)O)c1ccccc1
Type(s): Approved; Investigational
ATC code(s): N05CD07
Molecular Formula:: C16H13ClN2O2
Molecular Weight:: 300.740
Log P:: 1.9728
Hydrogen Bond Acceptor:: 4
Hydrogen Bond Donor:: 1
TPSA:: 52.9
CAS Number(s):: 846-50-4

Synonym(s)

Temazepam

Hydroxydiazepam

Methyloxazepam

Norkotral Tema

3-Hydroxydiazepam

Apo-Temazepam

Dasuen

Euhypnos

Gen-Temazepam

10.

Levanxol

11.

Nocturne

12.

Normison

13.

Normitab

14.

Nortem

15.

Novo-Temazepam

16.

Nu-Temazepam

17.

Oxydiazepam

18.

PMS-Temazepam

19.

Planum

20.

Pronervon T

21.

Remestan

22.

Restoril

23.

Ro-5-5345

24.

SaH 47-603

25.

Signopam

26.

Temaze

27.

Temazep Von Ct

28.

Temtabs

29.

Tenox

30.

WY-3917

31.

3 Hydroxydiazepam

32.

Apo Temazepam

33.

Gen Temazepam

34.

Novo Temazepam

35.

Nu Temazepam

36.

PMS Temazepam

37.

Ro 5 5345

38.

Ro55345

39.

SaH 47 603

40.

SaH 47603

41.

Tema, Norkotral

42.

Von Ct, Temazep

43.

WY 3917

44.

WY3917

External Link(s)

MeSH	D013693
PubChem Compound	5391
BindingDB	50408032
ChEBI	9435
CHEMBL	CHEMBL967
DrugBank	DB00231
DrugCentral	2585
IUPHAR/BPS Guide to PHARMACOLOGY	7300
KEGG	cpd:C07125 dr:D00370
Therapeutic Target Database	D04BNP

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Drug ineffective	FAERS: 153 Canada Vigilance: 9		Canada Vigilance OFFSIDES US FAERS
2	Somnolence	FAERS: 25 Canada Vigilance: 2		Canada Vigilance SIDER US FAERS
3	Feeling abnormal	FAERS: 18		SIDER US FAERS
4	Completed Suicide	FAERS: 17 Canada Vigilance: 2		Canada Vigilance US FAERS
5	Product quality issue	FAERS: 16		US FAERS
6	Anxiety	FAERS: 14		OFFSIDES SIDER US FAERS
7	Product substitution issue	FAERS: 14 Canada Vigilance: 1		Canada Vigilance US FAERS
8	Headache	FAERS: 12 Canada Vigilance: 2	913856 6105982	CTD SIDER Canada Vigilance US FAERS
9	Dizziness	FAERS: 11 Canada Vigilance: 1	18344728	CTD OFFSIDES SIDER Canada Vigilance US FAERS
10	Pharmaceutical product complaint	FAERS: 11		US FAERS
11	Wrong technique in product usage process	FAERS: 11		US FAERS
12	Nausea	FAERS: 10 Canada Vigilance: 1	913856 2884682 6105982	CTD OFFSIDES SIDER Canada Vigilance US FAERS
13	Tinnitus	FAERS: 10		OFFSIDES US FAERS
14	Agitation	FAERS: 9 Canada Vigilance: 3		Canada Vigilance SIDER US FAERS
15	Nervousness	FAERS: 9		SIDER US FAERS
16	Incorrect dose administered	FAERS: 8		US FAERS
17	Incorrect route of drug administration	FAERS: 8		US FAERS
18	Malaise	FAERS: 8 Canada Vigilance: 1		Canada Vigilance US FAERS
19	Somnambulism	FAERS: 8 Canada Vigilance: 1	2861195	CTD Canada Vigilance US FAERS
20	Amnesia	FAERS: 7 Canada Vigilance: 1	1929688	CTD OFFSIDES SIDER Canada Vigilance US FAERS
21	Dependence	FAERS: 7		OFFSIDES US FAERS
22	Pain	FAERS: 7		OFFSIDES US FAERS
23	Tremor	FAERS: 7		SIDER US FAERS
24	Unevaluable event	FAERS: 7		OFFSIDES US FAERS
25	Abdominal Pain	FAERS: 6		OFFSIDES US FAERS
26	Claustrophobia	FAERS: 6		US FAERS
27	Fatigue	FAERS: 6		OFFSIDES SIDER US FAERS
28	Vomiting	FAERS: 6		SIDER US FAERS
29	Burning sensation	FAERS: 5		US FAERS
30	Catatonia	FAERS: 5		US FAERS
31	Depressed mood	FAERS: 5		OFFSIDES US FAERS
32	Dissociation	FAERS: 5		US FAERS
33	Drug Dependence	FAERS: 5 Canada Vigilance: 1		Canada Vigilance US FAERS
34	Drug withdrawal syndrome	FAERS: 5		US FAERS
35	Dry skin	FAERS: 5		US FAERS
36	Gastrointestinal motility disorder	FAERS: 5		US FAERS
37	Middle insomnia	FAERS: 5		US FAERS
38	Neck Pain	FAERS: 5		US FAERS
39	Overdose	FAERS: 5		OFFSIDES US FAERS
40	Accidental exposure to product	FAERS: 4		US FAERS
41	Cerebrovascular accident	FAERS: 4		US FAERS
42	Constipation	FAERS: 4		SIDER US FAERS
43	Intentional product misuse	FAERS: 4		US FAERS
44	Restlessness	FAERS: 4		US FAERS
45	Suicide attempt	FAERS: 4		US FAERS
46	Abnormal sleep-related event	FAERS: 3		US FAERS
47	Asthenia	FAERS: 3		OFFSIDES SIDER US FAERS
48	Disorientation	FAERS: 3 Canada Vigilance: 2		Canada Vigilance SIDER US FAERS
49	Incontinence	FAERS: 3		OFFSIDES US FAERS
50	Lethargy	FAERS: 3		OFFSIDES SIDER US FAERS
51	Memory impairment	FAERS: 3		US FAERS
52	Mental status changes	FAERS: 3		OFFSIDES US FAERS
53	Paranoia	FAERS: 3		OFFSIDES US FAERS
54	Pruritus	FAERS: 3		SIDER US FAERS
55	Respiratory Depression	FAERS: 3		SIDER US FAERS
56	Respiratory Failure	FAERS: 3		OFFSIDES US FAERS
57	Syncope	FAERS: 3		SIDER US FAERS
58	Therapy change	FAERS: 3		US FAERS
59	Transcription medication error	FAERS: 3		US FAERS
60	nervous system disorder	FAERS: 3		US FAERS
61	Activities of daily living impaired	FAERS: 2		US FAERS
62	Alopecia	FAERS: 2		SIDER US FAERS
63	Anger	FAERS: 2		OFFSIDES US FAERS
64	Apathy	FAERS: 2		OFFSIDES US FAERS
65	Aphasia	FAERS: 2		US FAERS
66	Chest discomfort	FAERS: 2		US FAERS
67	Chromaturia	FAERS: 2		US FAERS
68	Delirium	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
69	Depressed Level of Consciousness	FAERS: 2		SIDER US FAERS
70	Drug Tolerance	FAERS: 2		US FAERS
71	Drug abuse	FAERS: 2		US FAERS
72	Drug dispensing error	FAERS: 2		US FAERS
73	Drug dose omission	FAERS: 2		US FAERS
74	Drug effect delayed	FAERS: 2		US FAERS
75	Drug toxicity	FAERS: 2		OFFSIDES US FAERS
76	Dysgeusia	FAERS: 2		OFFSIDES US FAERS
77	Echolalia	FAERS: 2		US FAERS
78	Emotional disorder	FAERS: 2		US FAERS
79	Emotional poverty	FAERS: 2		US FAERS
80	General physical health deterioration	FAERS: 2		OFFSIDES US FAERS
81	Gluten sensitivity	FAERS: 2		US FAERS
82	Hypersensitivity	FAERS: 2		SIDER US FAERS
83	Hypersomnia	FAERS: 2		US FAERS
84	Hyporeflexia	FAERS: 2		OFFSIDES US FAERS
85	Impaired work ability	FAERS: 2		US FAERS
86	Incorrect drug administration duration	FAERS: 2		US FAERS
87	Inflammation	FAERS: 2		US FAERS
88	Intentional product use issue	FAERS: 2		US FAERS
89	Intentional self-injury	FAERS: 2		US FAERS
90	Limb discomfort	FAERS: 2		US FAERS
91	Medication Error	FAERS: 2		US FAERS
92	Mental impairment	FAERS: 2		US FAERS
93	Mood swings	FAERS: 2		US FAERS
94	Myalgia	FAERS: 2		US FAERS
95	Myocardial Infarction	FAERS: 2		US FAERS
96	No adverse event	FAERS: 2		US FAERS
97	Nocturia	FAERS: 2		US FAERS
98	Palpitations	FAERS: 2		SIDER US FAERS
99	Personality Change	FAERS: 2		US FAERS
100	Polymyalgia Rheumatica	FAERS: 2		US FAERS
101	Product availability issue	FAERS: 2		US FAERS
102	Product difficult to swallow	FAERS: 2		US FAERS
103	Product formulation issue	FAERS: 2		US FAERS
104	Product physical consistency issue	FAERS: 2		US FAERS
105	Product solubility abnormal	FAERS: 2		US FAERS
106	Product storage error	FAERS: 2		US FAERS
107	Product taste abnormal	FAERS: 2		US FAERS
108	Restless Legs Syndrome	FAERS: 2		US FAERS
109	Sluggishness	FAERS: 2		US FAERS
110	Therapeutic response unexpected with drug substitution	FAERS: 2		US FAERS
111	Urticaria	FAERS: 2		US FAERS
112	Vertigo	FAERS: 2		SIDER US FAERS
113	Visual Impairment	FAERS: 2		SIDER US FAERS
114	Weight decreased	FAERS: 2		US FAERS
115	Wrong technique in drug usage process	FAERS: 2		US FAERS
116	treatment failure	FAERS: 2		US FAERS
117	Accidental overdose	FAERS: 1		US FAERS
118	Acne	FAERS: 1		US FAERS
119	Acute kidney injury	FAERS: 1		US FAERS
120	Adverse event	FAERS: 1		OFFSIDES US FAERS
121	Ageusia	FAERS: 1		SIDER US FAERS
122	Apparent death	FAERS: 1		US FAERS
123	Arthralgia	FAERS: 1		US FAERS
124	Asthma	FAERS: 1		OFFSIDES US FAERS
125	Back Pain	FAERS: 1		SIDER US FAERS
126	Bedridden	FAERS: 1		US FAERS
127	Bladder discomfort	FAERS: 1		US FAERS
128	Blood creatine phosphokinase increased	FAERS: 1		US FAERS
129	Blood glucose increased	FAERS: 1		US FAERS
130	Blood urine present	FAERS: 1		OFFSIDES US FAERS
131	Calciphylaxis	FAERS: 1		US FAERS
132	Capsule issue	FAERS: 1		US FAERS
133	Capsule physical issue	FAERS: 1		US FAERS
134	Cardiac Arrest	FAERS: 1		US FAERS
135	Chills	FAERS: 1		US FAERS
136	Clumsiness	FAERS: 1		US FAERS
137	Counterfeit product administered	FAERS: 1		US FAERS
138	Cyanosis	FAERS: 1		OFFSIDES US FAERS
139	Dark circles under eyes	FAERS: 1		US FAERS
140	Dehydration	FAERS: 1		OFFSIDES US FAERS
141	Disability	FAERS: 1		US FAERS
142	Drowning	FAERS: 1		US FAERS
143	Drug dispensed to wrong patient	FAERS: 1		US FAERS
144	Drug prescribing error	FAERS: 1		US FAERS
145	Drug screen negative	FAERS: 1		US FAERS
146	Dysarthria	FAERS: 1		SIDER US FAERS
147	Dyspepsia	FAERS: 1		OFFSIDES US FAERS
148	Eye pain	FAERS: 1		OFFSIDES US FAERS
149	Eyelids pruritus	FAERS: 1		US FAERS
150	Feeling Cold	FAERS: 1		OFFSIDES US FAERS
151	Frustration	FAERS: 1		US FAERS
152	Gangrene	FAERS: 1		US FAERS
153	Hyperphagia	FAERS: 1		US FAERS
154	Hypotension	FAERS: 1		SIDER US FAERS
155	Immobile	FAERS: 1		US FAERS
156	Impaired driving ability	FAERS: 1		US FAERS
157	Inappropriate schedule of drug administration	FAERS: 1		US FAERS
158	Incoherent	FAERS: 1		US FAERS
159	Incorrect product administration duration	FAERS: 1		US FAERS
160	Infective exacerbation of chronic obstructive airways disease	FAERS: 1		US FAERS
161	Intentional drug misuse	FAERS: 1		OFFSIDES US FAERS
162	Intercepted medication error	FAERS: 1		US FAERS
163	Intestinal Perforation	FAERS: 1		US FAERS
164	Limb operation	FAERS: 1		US FAERS
165	Loss of personal independence in daily activities	FAERS: 1		US FAERS
166	Multiple drug overdose	FAERS: 1		OFFSIDES US FAERS
167	Multiple drug overdose intentional	FAERS: 1		US FAERS
168	Muscle necrosis	FAERS: 1		US FAERS
169	Muscle tightness	FAERS: 1		US FAERS
170	Musculoskeletal stiffness	FAERS: 1		OFFSIDES US FAERS
171	Mutism	FAERS: 1		US FAERS
172	Myoglobin urine present	FAERS: 1		US FAERS
173	Nasal discomfort	FAERS: 1		US FAERS
174	Oropharyngeal pain	FAERS: 1		OFFSIDES US FAERS
175	Peripheral arterial occlusive disease	FAERS: 1		US FAERS
176	Pharmaceutical product counterfeit	FAERS: 1		US FAERS
177	Poor quality sleep	FAERS: 1		US FAERS
178	Post procedural complication	FAERS: 1		US FAERS
179	Poverty of speech	FAERS: 1		US FAERS
180	Prescription drug used without a prescription	FAERS: 1		US FAERS
181	Priapism	FAERS: 1	10327919	CTD US FAERS
182	Procedural complication	FAERS: 1		US FAERS
183	Product administered to patient of inappropriate age	FAERS: 1		US FAERS
184	Product administration error	FAERS: 1		US FAERS
185	Product identification number issue	FAERS: 1		US FAERS
186	Product measured potency issue	FAERS: 1		US FAERS
187	Product physical issue	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
188	Product use issue	FAERS: 1		US FAERS
189	Reaction to drug excipients	FAERS: 1		US FAERS
190	Reaction to excipient	FAERS: 1		US FAERS
191	Respiratory distress	FAERS: 1		US FAERS
192	Sinus headache	FAERS: 1		US FAERS
193	Skin irritation	FAERS: 1		US FAERS
194	Sleep-related eating disorder	FAERS: 1		US FAERS
195	Stupor	FAERS: 1		US FAERS
196	Therapeutic response unexpected	FAERS: 1		US FAERS
197	Thirst	FAERS: 1		US FAERS
198	Throat irritation	FAERS: 1		US FAERS
199	Toxicity to various agents	FAERS: 1		US FAERS
200	Troponin I increased	FAERS: 1		US FAERS
201	Unresponsive to stimuli	FAERS: 1		US FAERS
202	Urge Incontinence	FAERS: 1		US FAERS
203	Urinary Retention	FAERS: 1		US FAERS
204	Urinary tract infection	FAERS: 1		US FAERS
205	Vaginal burning sensation	FAERS: 1		US FAERS
206	Vasospasm	FAERS: 1		US FAERS
207	Vein pain	FAERS: 1		US FAERS
208	Victim of child abuse	FAERS: 1		US FAERS
209	Yawning	FAERS: 1		US FAERS
210	Abdominal discomfort			OFFSIDES SIDER
211	Abnormal vision			OFFSIDES
212	Abuse			OFFSIDES
213	Acid reflux			OFFSIDES
214	Acute myocardial infarction			OFFSIDES
215	Adenocarcinoma			OFFSIDES
216	Agoraphobia			OFFSIDES
217	Agranulocytosis			SIDER
218	Agraphia			OFFSIDES
219	Alcohol poisoning			OFFSIDES
220	Alkaline phosphatase serum increased			SIDER
221	Alveolitis			OFFSIDES
222	Anal sphincter atony			OFFSIDES
223	Analgesia			OFFSIDES
224	Angioedema			OFFSIDES
225	Anhedonia			OFFSIDES
226	Ankle Fracture			OFFSIDES
227	Anorexia			OFFSIDES SIDER
228	Anosmia			OFFSIDES
229	Antidepressant drug clearance decreased			OFFSIDES
230	Aortic valve sclerosis			OFFSIDES
231	Apnea			OFFSIDES
232	Arteriosclerosis			OFFSIDES
233	Arthritis			OFFSIDES
234	Asbestosis			OFFSIDES
235	Ataxia			SIDER
236	Atelectasis			OFFSIDES
237	Autonomic neuropathy			OFFSIDES
238	Basal cell carcinoma			OFFSIDES
239	Biliary sepsis			OFFSIDES
240	Blood Glucose			OFFSIDES
241	Blood albumin decreased			OFFSIDES
242	Blood alkaline phosphatase increased			OFFSIDES SIDER
243	Blood amylase decreased			OFFSIDES
244	Blood chloride decreased			OFFSIDES
245	Blood cholesterol			OFFSIDES
246	Blood glucose decreased			OFFSIDES
247	Blood potassium decreased			OFFSIDES
248	Blood potassium increased			OFFSIDES
249	Blood pressure fluctuation			OFFSIDES
250	Blood pressure immeasurable			OFFSIDES
251	Blood sodium			OFFSIDES
252	Blood testosterone decreased			OFFSIDES
253	Blood triglycerides increased			OFFSIDES
254	Blood urea increased			OFFSIDES
255	Blurred vision			OFFSIDES
256	Bone density decreased			OFFSIDES
257	Bone lesion			OFFSIDES
258	Bone pain			OFFSIDES
259	Borderline Personality Disorder			OFFSIDES
260	Bradycardia			OFFSIDES
261	Brain natriuretic peptide increased			OFFSIDES
262	Breakthrough Pain			OFFSIDES
263	Breast Microcalcification			OFFSIDES
264	Breast tenderness			OFFSIDES
265	Bronchoscopy			OFFSIDES
266	Bruxism			OFFSIDES
267	Bullous lung disease			OFFSIDES
268	Candiduria			OFFSIDES
269	Cardiac Hypertrophy			OFFSIDES
270	Cartilage injury			OFFSIDES
271	Cataract			OFFSIDES
272	Catheter related infection			OFFSIDES
273	Catheter site related reaction			OFFSIDES
274	Cellulitis			OFFSIDES
275	Central venous catheter removal			OFFSIDES
276	Cerebral artery stenosis			OFFSIDES
277	Cerebral atrophy			OFFSIDES
278	Cervicobrachial syndrome			OFFSIDES
279	Chest Pain			OFFSIDES
280	Choking sensation			OFFSIDES
281	Choking			OFFSIDES
282	Cholecystitis infective			OFFSIDES
283	Chronic Obstructive Airway Disease			OFFSIDES
284	Cirrhosis			OFFSIDES
285	Clostridium difficile colitis			OFFSIDES
286	Coccidioidomycosis			OFFSIDES
287	Cold sweat			OFFSIDES
288	Colitis			OFFSIDES
289	Colon adenoma			OFFSIDES
290	Confabulation			OFFSIDES
291	Confusion		1929688	CTD
292	Congenital heart disease			OFFSIDES
293	Congenital tricuspid valve incompetence			OFFSIDES
294	Conjunctival deposit			OFFSIDES
295	Cramps of lower extremities			SIDER
296	Crying			OFFSIDES
297	Cytomegalovirus chorioretinitis			OFFSIDES
298	Deafness			OFFSIDES
299	Debridement			OFFSIDES
300	Demyelination			OFFSIDES
301	Dental abscess			OFFSIDES
302	Dental caries			OFFSIDES
303	Denture wearer			OFFSIDES
304	Depressive disorder		10327919	CTD
305	Diabetes			OFFSIDES
306	Diabetes Insipidus			OFFSIDES
307	Diabetes mellitus inadequate control			OFFSIDES
308	Diabetic gastropathy			OFFSIDES
309	Diarrhea			OFFSIDES
310	Diplopia			SIDER
311	Disease Progression			OFFSIDES
312	Diverticulitis			OFFSIDES
313	Diverticulum			OFFSIDES
314	Dreaming excessive			SIDER
315	Drowsiness			SIDER
316	Drug addict			OFFSIDES
317	Drug administered at inappropriate site			OFFSIDES
318	Drug withdrawal convulsions			OFFSIDES
319	Drug withdrawal headache			OFFSIDES
320	Dysphonia			OFFSIDES
321	Dysthymic Disorder			OFFSIDES
322	Dysuria			OFFSIDES
323	Eczema			OFFSIDES
324	Ejection Fraction Decreased			OFFSIDES
325	Electrocardiogram poor R-wave progression			OFFSIDES
326	Electromechanical dissociation			OFFSIDES
327	Elevated mood			OFFSIDES
328	Emotional distress			OFFSIDES
329	Empyema			OFFSIDES
330	Encephalomalacia			OFFSIDES
331	Endodontic procedure			OFFSIDES
332	Enteritis			OFFSIDES
333	Enterococcal sepsis			OFFSIDES
334	Epistaxis			OFFSIDES
335	Erectile dysfunction			OFFSIDES SIDER
336	Euphoric mood			SIDER
337	Exposure to chemical pollution			OFFSIDES
338	Failure to Thrive			OFFSIDES
339	Fasciitis			OFFSIDES
340	Fatty Liver		6146546	CTD OFFSIDES
341	Feelings of worthlessness			OFFSIDES
342	Femoral pulse			OFFSIDES
343	Fibromyalgia			OFFSIDES
344	Flank Pain			OFFSIDES
345	Formication			OFFSIDES
346	Fungal peritonitis			OFFSIDES
347	Gambling			OFFSIDES
348	Gastroenteritis			OFFSIDES
349	General symptom			OFFSIDES
350	Granulocytosis			OFFSIDES
351	Hallucinations		1929688 17038091	CTD
352	Hemicephalalgia			OFFSIDES
353	Heparin-induced thrombocytopenia			OFFSIDES
354	Hepatitis B positive			OFFSIDES
355	Hepatitis C			OFFSIDES
356	Hiccough			OFFSIDES
357	Hidradenitis			OFFSIDES
358	Hip surgery			OFFSIDES
359	Hostility			SIDER
360	Hyperreflexia			OFFSIDES
361	Hypertensive heart disease			OFFSIDES
362	Hyperventilation			OFFSIDES
363	Hypokinesia			OFFSIDES
364	Hypotension, Orthostatic		9518913 12500019	CTD
365	Hypoxia			OFFSIDES
366	Immunosuppression			OFFSIDES
367	Impaired self-care			OFFSIDES
368	Impetigo			OFFSIDES
369	Implant site reaction			OFFSIDES
370	Injection site infection			OFFSIDES
371	Intention tremor			OFFSIDES
372	Intercostal neuralgia			OFFSIDES
373	Intervertebral Disc Degeneration			OFFSIDES
374	Intervertebral disc disorder			OFFSIDES
375	Ischemia		8181625	CTD
376	Joint injury			OFFSIDES
377	Kidney Failure			OFFSIDES
378	Laryngospasm			OFFSIDES
379	Leukocytosis			SIDER
380	Leukopenia neonatal			OFFSIDES
381	Liver scan abnormal			OFFSIDES
382	Loose tooth			OFFSIDES
383	Lumbar radiculopathy			OFFSIDES
384	Malignant Hypertension			OFFSIDES
385	Malignant neoplasm progression			OFFSIDES
386	Mallory-Weiss Syndrome			OFFSIDES
387	Malocclusion			OFFSIDES
388	Medication residue			OFFSIDES
389	Memory Disorders		2884682	CTD
390	Micrographic skin surgery			OFFSIDES
391	Migraine with Aura			OFFSIDES
392	Muscle Weakness			OFFSIDES
393	Musculoskeletal Pain			OFFSIDES
394	Mycosis Fungoides			OFFSIDES
395	Nephrolithiasis			OFFSIDES
396	Neuralgia			OFFSIDES
397	Neutropenic sepsis			OFFSIDES
398	Nonspecific reaction			OFFSIDES
399	Nystagmus			SIDER
400	Obsessive thoughts			OFFSIDES
401	Open reduction of fracture			OFFSIDES
402	Oral mucosal erythema			OFFSIDES
403	Oropharyngeal discomfort			OFFSIDES
404	Osteopenia			OFFSIDES
405	Osteoporosis			OFFSIDES
406	PCO2 decreased			OFFSIDES
407	Pacemaker complication			OFFSIDES
408	Panic Disorder			OFFSIDES
409	Panophthalmitis			OFFSIDES
410	Paresthesia		2884682	CTD
411	Parvovirus B19 serology positive			OFFSIDES
412	Pericardial effusion			OFFSIDES
413	Perirectal abscess			OFFSIDES
414	Pleocytosis			OFFSIDES
415	Pleural decortication			OFFSIDES
416	Pneumothorax			OFFSIDES
417	Poor peripheral circulation			OFFSIDES
418	Poor quality drug administered			OFFSIDES
419	Primary sequestrum			OFFSIDES
420	Proctitis			OFFSIDES
421	Proctocolitis			OFFSIDES
422	Product used for unknown indication	Canada Vigilance: 1		Canada Vigilance
423	Productive Cough			OFFSIDES
424	Prostate cancer recurrent			OFFSIDES
425	Protein total decreased			OFFSIDES
426	Protein urine present			SIDER
427	Proteinuria			SIDER
428	Psychomotor Agitation		2861195	CTD
429	Pulmonary congestion			OFFSIDES
430	Pulmonary function test decreased			SIDER
431	QRS axis abnormal			OFFSIDES
432	Rales			OFFSIDES
433	Rectal discharge			OFFSIDES
434	Rectal fissure			OFFSIDES
435	Regurgitation			OFFSIDES
436	Renal Artery Stenosis			OFFSIDES
437	Renal Insufficiency		7816302	CTD
438	Renal cyst			OFFSIDES
439	Renal tubular necrosis			OFFSIDES
440	Retroperitoneal lymphadenopathy			OFFSIDES
441	Rhabdomyolysis		7816302	CTD
442	Rhinalgia			OFFSIDES
443	Rhinorrhea			OFFSIDES
444	Right ventricular systolic pressure increased			OFFSIDES
445	Scab			OFFSIDES
446	Sciatica			SIDER
447	Secretion discharge			OFFSIDES
448	Sequestrectomy			OFFSIDES
449	Shock			SIDER
450	Sigmoiditis			OFFSIDES
451	Skeletal injury			OFFSIDES
452	Skin laceration			OFFSIDES
453	Skin lesion			OFFSIDES
454	Sleep Initiation and Maintenance Disorders		View details 1613015 2015735 2884682 6105982 8070501 15341891 18344728	CTD
455	Sleep Wake Disorders		913856 6141114	CTD
456	Slurred speech			SIDER
457	Spondylolisthesis			OFFSIDES
458	Staphylococcal Scalded Skin Syndrome			OFFSIDES
459	Stevens-Johnson Syndrome			OFFSIDES
460	Stress			OFFSIDES
461	Subcutaneous Abscess			OFFSIDES
462	Substance Withdrawal Syndrome		2015735 16226742	CTD
463	Superficial Thrombophlebitis			OFFSIDES
464	Suprapubic pain			OFFSIDES
465	Supraventricular tachycardia			OFFSIDES
466	Tachycardia		2894218	CTD SIDER
467	Temporal Arteritis			OFFSIDES
468	Tenosynovitis			OFFSIDES
469	Tension			SIDER
470	Therapeutic response changed	Canada Vigilance: 1		Canada Vigilance
471	Therapy non-responder			OFFSIDES
472	Thrombocytopenia			SIDER
473	Thrombosis in device			OFFSIDES
474	Tongue biting			OFFSIDES
475	Tooth Extraction			OFFSIDES
476	Tooth Infection			OFFSIDES
477	Tooth Loss			OFFSIDES
478	Tracheal fistula			OFFSIDES
479	Troponin increased			OFFSIDES
480	Ulcer			OFFSIDES
481	Unresponsive to pain stimuli			OFFSIDES
482	Vascular calcification			OFFSIDES
483	Venous Thrombosis		2882767	CTD
484	Venous thrombosis limb			OFFSIDES
485	Visual disturbance			OFFSIDES SIDER
486	Weight Gain			OFFSIDES
487	Wound dehiscence			OFFSIDES
488	Wound infection staphylococcal			OFFSIDES
489	jaundice			SIDER

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