MetaADEDB 2.0 @ LMMD
Felbamate
(WKGXYQFOCVYPAC-UHFFFAOYSA-N)
Structure
SMILES
NC(=O)OCC(c1ccccc1)COC(=O)N
Type(s)
Approved
ATC code(s)
N03AX10
Molecular Formula:
C11H14N2O4
Molecular Weight:
238.240
Log P:
2.3614
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
104.64
CAS Number(s):
25451-15-4
Synonym(s)
1.
Felbamate
2.
(3-Carbamoyloxy-2-phenyl-propyl) carbamate
3.
2-Phenyl-1,3-propanediol dicarbamate
4.
ADD-03055
5.
Felbamyl
6.
Felbatol
7.
Taloxa
8.
W-554
9.
2 Phenyl 1,3 propanediol dicarbamate
10.
ADD 03055
11.
ADD03055
12.
W 554
13.
W554
External Link(s)
MeSHD000078328
PubChem Compound3331
BindingDB50088430
ChEBI4995
CHEMBLCHEMBL1094
DrugBankDB00949
DrugCentral1140
IUPHAR/BPS Guide to PHARMACOLOGY5473
KEGGcpd:C07501
dr:D00536
Therapeutic Target DatabaseD05KON
ZINC1530803
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug withdrawal convulsionsFAERS: 9US FAERS
2Product substitution issueFAERS: 9US FAERS
3Drug ineffectiveFAERS: 7US FAERS
4AstheniaFAERS: 5SIDER
US FAERS
5Drug dose omissionFAERS: 5US FAERS
6EpilepsyFAERS: 5

View details

7705426
8667248
8848816
8854308
8968330
9169285
 		CTD
US FAERS
7Drug effect incompleteFAERS: 4US FAERS
8Adverse eventFAERS: 3US FAERS
9DiplopiaFAERS: 3SIDER
US FAERS
10DizzinessFAERS: 3SIDER
US FAERS
11Incorrect dose administeredFAERS: 3OFFSIDES
US FAERS
12NauseaFAERS: 3SIDER
US FAERS
13NephrolithiasisFAERS: 3US FAERS
14VomitingFAERS: 39848129CTD
SIDER
US FAERS
15Depressed Level of ConsciousnessFAERS: 2SIDER
US FAERS
16DysarthriaFAERS: 2SIDER
US FAERS
17Intentional drug misuseFAERS: 2US FAERS
18MalaiseFAERS: 2SIDER
US FAERS
19Memory impairmentFAERS: 2US FAERS
20OsteoporosisFAERS: 2OFFSIDES
US FAERS
21OverdoseFAERS: 2US FAERS
22Product quality issueFAERS: 2US FAERS
23StomatitisFAERS: 2US FAERS
24Abdominal PainFAERS: 1SIDER
US FAERS
25Abdominal discomfortFAERS: 1US FAERS
26AgitationFAERS: 1SIDER
US FAERS
27AgranulocytosisFAERS: 1SIDER
US FAERS
28AmnesiaFAERS: 1US FAERS
29Amylase increasedFAERS: 1US FAERS
30Anaphylactic shockFAERS: 1SIDER
US FAERS
31AngerFAERS: 1US FAERS
32Blood alkaline phosphatase increasedFAERS: 1SIDER
US FAERS
33Bone painFAERS: 1US FAERS
34BronchitisFAERS: 1US FAERS
35Cervix carcinomaFAERS: 1US FAERS
36ChillsFAERS: 1SIDER
US FAERS
37CryingFAERS: 1OFFSIDES
US FAERS
38Culture urine positiveFAERS: 1US FAERS
39Device difficult to useFAERS: 1US FAERS
40DiscomfortFAERS: 1SIDER
US FAERS
41Drug administration errorFAERS: 1OFFSIDES
US FAERS
42Drug level below therapeuticFAERS: 1US FAERS
43DysuriaFAERS: 1SIDER
US FAERS
44Enterobacter sepsisFAERS: 1US FAERS
45FatigueFAERS: 1SIDER
US FAERS
46Feeling abnormalFAERS: 1SIDER
US FAERS
47Feeling jitteryFAERS: 1US FAERS
48HeadacheFAERS: 1SIDER
US FAERS
49HepatomegalyFAERS: 19848129CTD
US FAERS
50HypervigilanceFAERS: 1US FAERS
51HypopituitarismFAERS: 1US FAERS
52Impaired work abilityFAERS: 1US FAERS
53Incorrect route of drug administrationFAERS: 1US FAERS
54InflammationFAERS: 1US FAERS
55LacerationFAERS: 1US FAERS
56Lennox-Gastaut syndromeFAERS: 1US FAERS
57Lipase increasedFAERS: 1US FAERS
58MacrocytosisFAERS: 1US FAERS
59MalabsorptionFAERS: 1US FAERS
60Mallory-Weiss SyndromeFAERS: 1US FAERS
61MyalgiaFAERS: 1SIDER
US FAERS
62MyoclonusFAERS: 1US FAERS
63NasopharyngitisFAERS: 1US FAERS
64No adverse eventFAERS: 1US FAERS
65NystagmusFAERS: 1SIDER
US FAERS
66PalpitationsFAERS: 1SIDER
US FAERS
67PancytopeniaFAERS: 1SIDER
US FAERS
68Personality ChangeFAERS: 1US FAERS
69Poor peripheral circulationFAERS: 1US FAERS
70Product formulation issueFAERS: 1US FAERS
71Sensation of blood flowFAERS: 1US FAERS
72SinusitisFAERS: 1SIDER
US FAERS
73SomnolenceFAERS: 1SIDER
US FAERS
74Squamous cell carcinomaFAERS: 1US FAERS
75Therapeutic response unexpectedFAERS: 1US FAERS
76Therapy cessationFAERS: 1US FAERS
77Toxicity to various agentsFAERS: 1US FAERS
78TremorFAERS: 19848129CTD
SIDER
US FAERS
79Unable to afford prescribed medicationFAERS: 1US FAERS
80Urinary tract infectionFAERS: 1SIDER
US FAERS
81Weight decreasedFAERS: 1SIDER
US FAERS
82AbasiaOFFSIDES
83Abnormal visionSIDER
84AcneSIDER
85Acquired megacolonSIDER
86Acute bronchitisOFFSIDES
87Aggressive reactionSIDER
88Alanine Aminotransferase IncreasedSIDER
89AlopeciaSIDER
90Anaphylactoid ReactionSIDER
91AnencephalySIDER
92AnorexiaSIDER
93AnxietySIDER
94ApathySIDER
95ArthralgiaSIDER
96Aspartate Aminotransferase IncreasedSIDER
97AsthmaSIDER
98Ataxia9848129CTD
SIDER
99Atrial FibrillationSIDER
100Atrial arrhythmiaSIDER
101Blepharoptosis9848129CTD
102Blood lactate dehydrogenase increasedSIDER
103Body odorSIDER
104Bone density decreasedOFFSIDES
105BradycardiaOFFSIDES
SIDER
106Brain Ischemia8232947
8685935		CTD
107Bullous eruptionSIDER
108Cardiac ArrestSIDER
109CardiotoxicityOFFSIDES
110Catalepsy7845605CTD
111Central Nervous System InfectionOFFSIDES
112Chemical and Drug Induced Liver Injury24085192CTD
113Chemotherapeutic drug level increasedOFFSIDES
114Chest PainSIDER
115ChoreoathetosisSIDER
116Circumstance or information capable of leading to medication errorOFFSIDES
117Cognition Disorders8854308CTD
118ConjunctivitisSIDER
119ConstipationSIDER
120CystOFFSIDES
121DehydrationOFFSIDES
SIDER
122DermatitisSIDER
123Diarrhea9848129CTD
124Disease ProgressionOFFSIDES
125Disseminated Intravascular CoagulationSIDER
126Drug Eruptions12926190CTD
127DysgeusiaSIDER
128Dyskinesia, Drug-Induced7845605CTD
129DyspepsiaSIDER
130Embolism limbSIDER
131EncephaloceleSIDER
132EnteritisSIDER
133EosinophiliaSIDER
134Epilepsies, Partial1944909
11518421		CTD
135Epilepsy, Reflex7713059CTD
136Epileptic encephalopathy, Lennox-Gastaut type10215667CTD
137EpistaxisSIDER
138Erythema MultiformeSIDER
139Escherichia urinary tract infectionOFFSIDES
140Euphoric moodSIDER
141Flat affectSIDER
142FlatulenceSIDER
143FlushingSIDER
144GangreneSIDER
145Gastric DilatationSIDER
146Gastric ulcerSIDER
147GastritisSIDER
148Gastrointestinal PainSIDER
149GlossitisSIDER
150HemiparesisOFFSIDES
151HepatitisSIDER
152Hepatorenal SyndromeSIDER
153HyperpyrexiaSIDER
154HypotensionSIDER
155Hypoxia8232947CTD
156IleusSIDER
157InfectionSIDER
158Influenza-like symptomsSIDER
159Intestinal ObstructionSIDER
160Keratoconjunctivitis Sicca11518421CTD
161Kidney Calculi9848129CTD
162Lactic dehydrogenase activity increasedSIDER
163Lethargy8854308CTD
164LeukocytosisSIDER
165Leukopenia neonatalOFFSIDES
166LeukopeniaSIDER
167Lichen PlanusSIDER
168Livedo ReticularisSIDER
169Lung InjuryOFFSIDES
170LymphadenopathySIDER
171LymphomaSIDER
172Manic psychosisSIDER
173MegacolonSIDER
174MicrocephalySIDER
175MononeuritisSIDER
176Mood Disorders8854308CTD
177Mood swingsSIDER
178Movement Disorders22107891CTD
179Musculoskeletal discomfortSIDER
180Necrosis8232947CTD
SIDER
181NephrosisSIDER
182Nephrotic SyndromeSIDER
183Nerve Degeneration8821739
12192617		CTD
184NervousnessSIDER
185Otitis MediaSIDER
186Pain11750907CTD
SIDER
187PancreatitisSIDER
188ParanoiaSIDER
189Paranoid reactionSIDER
190Parkinsonian Disorders7845605CTD
191Peripheral embolismSIDER
192PharyngitisSIDER
193Photosensitivity allergic reactionSIDER
194PneumoniaSIDER
195PruritusSIDER
196Psychoses, Substance-Induced8854308CTD
197Pulmonary function test decreasedSIDER
198PurpuraSIDER
199Respiration Disorders9848129CTD
200Respiratory DepressionSIDER
201Respiratory FailureSIDER
202Respiratory InsufficiencySIDER
203Reticulocyte count decreasedOFFSIDES
204Retrosternal painSIDER
205RhabdomyolysisSIDER
206RhinitisSIDER
207ScotomaOFFSIDES
208Seizures

View details

1563341
1664105
3004930
3107974
7529182
7875235
8058587
8480078
8951966
9178952
9553992
9848129
10454489
10861587
11224288
11738929
14581726
15461671
17901576
18253065
22107891
 		CTD
209SepsisSIDER
210Status Epilepticus10691107
21190901		CTD
SIDER
211Stevens-Johnson Syndrome25811541CTD
SIDER
212Stomach dilation procedureSIDER
213StuporSIDER
214Subarachnoid Hemorrhage17439355CTD
215Substance Withdrawal Syndrome8747757CTD
216Sudden deathOFFSIDES
SIDER
217Sudden infant death syndromeSIDER
218Suicide attemptSIDER
219Supraventricular tachycardiaSIDER
220SweatingSIDER
221TachycardiaSIDER
222TensionSIDER
223ThrombocytopeniaSIDER
224ThrombophlebitisSIDER
225Toxic Epidermal NecrolysisSIDER
226Tympanic Membrane PerforationOFFSIDES
227Ulcerative stomatitisSIDER
228Ureteral Calculi11380578CTD
229Urinary Calculi9848129CTD
230Urinary IncontinenceSIDER
231Urinary RetentionSIDER
232UrticariaSIDER
233Vascular purpuraSIDER
234VasculitisSIDER
235Visual ImpairmentSIDER
236Weight GainOFFSIDES
237jaundiceSIDER
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