Tramadol hydrochloride and acetaminophen
(UFLWHLMSTCRAJP-WUTOMRCLSA-N)
Structure
- SMILES
- CC(=O)Nc1ccc(cc1)O.COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C.Cl
- Molecular Formula:
- C24H35ClN2O4
- Molecular Weight:
- 450.999
- Log P:
- 4.8602
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 4
- TPSA:
- 82.03
- CAS Number(s):
- 147630-10-2
Synonym(s)
1.
Tramadol hydrochloride and acetaminophen
External Link(s)
| PubChem Compound | 24847942 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Vomiting | FAERS: 27 | US FAERS | |
| 2 | Dizziness | FAERS: 21 | US FAERS | |
| 3 | Nausea | FAERS: 19 | US FAERS | |
| 4 | Somnolence | FAERS: 17 | US FAERS | |
| 5 | Malaise | FAERS: 11 | US FAERS | |
| 6 | Constipation | FAERS: 9 | US FAERS | |
| 7 | Drug ineffective | FAERS: 6 | US FAERS | |
| 8 | Urinary Retention | FAERS: 6 | US FAERS | |
| 9 | Blood potassium increased | FAERS: 5 | US FAERS | |
| 10 | Dysuria | FAERS: 5 | US FAERS | |
| 11 | Feeling abnormal | FAERS: 5 | US FAERS | |
| 12 | Incorrect dose administered | FAERS: 5 | US FAERS | |
| 13 | Suicide attempt | FAERS: 5 | US FAERS | |
| 14 | Anxiety | FAERS: 4 | US FAERS | |
| 15 | Gastric ulcer | FAERS: 4 | US FAERS | |
| 16 | Pruritus | FAERS: 4 | US FAERS | |
| 17 | Urinary Incontinence | FAERS: 4 | US FAERS | |
| 18 | Abdominal Pain | FAERS: 3 | US FAERS | |
| 19 | Acute respiratory failure | FAERS: 3 | US FAERS | |
| 20 | Alanine Aminotransferase Increased | FAERS: 3 | US FAERS | |
| 21 | Aspartate Aminotransferase Increased | FAERS: 3 | US FAERS | |
| 22 | Asthma | FAERS: 3 | US FAERS | |
| 23 | Blood lactate dehydrogenase increased | FAERS: 3 | US FAERS | |
| 24 | Dementia | FAERS: 3 | US FAERS | |
| 25 | Depressed Level of Consciousness | FAERS: 3 | US FAERS | |
| 26 | Disorientation | FAERS: 3 | US FAERS | |
| 27 | Drug Dependence | FAERS: 3 | US FAERS | |
| 28 | Headache | FAERS: 3 | US FAERS | |
| 29 | Hypersomnia | FAERS: 3 | US FAERS | |
| 30 | Hypotension | FAERS: 3 | US FAERS | |
| 31 | Ileus | FAERS: 3 | US FAERS | |
| 32 | Medication Error | FAERS: 3 | US FAERS | |
| 33 | Pain | FAERS: 3 | US FAERS | |
| 34 | Pneumonia | FAERS: 3 | US FAERS | |
| 35 | Product use in unapproved indication | FAERS: 3 | US FAERS | |
| 36 | Tachycardia | FAERS: 3 | US FAERS | |
| 37 | Tremor | FAERS: 3 | US FAERS | |
| 38 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 39 | Angina Pectoris | FAERS: 2 | US FAERS | |
| 40 | Ataxia | FAERS: 2 | US FAERS | |
| 41 | Chest discomfort | FAERS: 2 | US FAERS | |
| 42 | Diabetes Mellitus | FAERS: 2 | US FAERS | |
| 43 | Drug prescribing error | FAERS: 2 | US FAERS | |
| 44 | Drug withdrawal syndrome | FAERS: 2 | US FAERS | |
| 45 | Dysarthria | FAERS: 2 | US FAERS | |
| 46 | Eczema | FAERS: 2 | US FAERS | |
| 47 | Epigastric discomfort | FAERS: 2 | US FAERS | |
| 48 | Hypersensitivity | FAERS: 2 | US FAERS | |
| 49 | Inadequate analgesia | FAERS: 2 | US FAERS | |
| 50 | Myoclonus | FAERS: 2 | US FAERS | |
| 51 | No adverse event | FAERS: 2 | US FAERS | |
| 52 | Overdose | FAERS: 2 | US FAERS | |
| 53 | Pallor | FAERS: 2 | US FAERS | |
| 54 | Palpitations | FAERS: 2 | US FAERS | |
| 55 | Photophobia | FAERS: 2 | US FAERS | |
| 56 | Product substitution issue | FAERS: 2 | US FAERS | |
| 57 | Pulmonary Fibrosis | FAERS: 2 | US FAERS | |
| 58 | Restlessness | FAERS: 2 | US FAERS | |
| 59 | Sinus bradycardia | FAERS: 2 | US FAERS | |
| 60 | Syncope | FAERS: 2 | US FAERS | |
| 61 | Thirst | FAERS: 2 | US FAERS | |
| 62 | Thrombocytopenia | FAERS: 2 | US FAERS | |
| 63 | Urticaria | FAERS: 2 | US FAERS | |
| 64 | Vertigo | FAERS: 2 | US FAERS | |
| 65 | treatment failure | FAERS: 2 | US FAERS | |
| 66 | Accidental exposure to product by child | FAERS: 1 | US FAERS | |
| 67 | Adverse event | FAERS: 1 | US FAERS | |
| 68 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 69 | Amnestic Disorder | FAERS: 1 | US FAERS | |
| 70 | Analgesic drug level increased | FAERS: 1 | US FAERS | |
| 71 | Angioedema | FAERS: 1 | US FAERS | |
| 72 | Anuria | FAERS: 1 | US FAERS | |
| 73 | Aphasia | FAERS: 1 | US FAERS | |
| 74 | Arthropathy | FAERS: 1 | US FAERS | |
| 75 | Asthenia | FAERS: 1 | US FAERS | |
| 76 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 77 | Atrioventricular Block | FAERS: 1 | US FAERS | |
| 78 | Back Pain | FAERS: 1 | US FAERS | |
| 79 | Benign Prostatic Hyperplasia | FAERS: 1 | US FAERS | |
| 80 | Bladder tamponade | FAERS: 1 | US FAERS | |
| 81 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 82 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 83 | Blood urea increased | FAERS: 1 | US FAERS | |
| 84 | Bone abscess | FAERS: 1 | US FAERS | |
| 85 | Bradycardia | FAERS: 1 | US FAERS | |
| 86 | Bronchial Hyperreactivity | FAERS: 1 | US FAERS | |
| 87 | Bronchospasm | FAERS: 1 | US FAERS | |
| 88 | Cancer Pain | FAERS: 1 | US FAERS | |
| 89 | Chills | FAERS: 1 | US FAERS | |
| 90 | Chromaturia | FAERS: 1 | US FAERS | |
| 91 | Cold sweat | FAERS: 1 | US FAERS | |
| 92 | Completed Suicide | FAERS: 1 | US FAERS | |
| 93 | Creatinine renal clearance decreased | FAERS: 1 | US FAERS | |
| 94 | Cytolytic hepatitis | FAERS: 1 | US FAERS | |
| 95 | Dehydration | FAERS: 1 | US FAERS | |
| 96 | Delirium | FAERS: 1 | US FAERS | |
| 97 | Diplopia | FAERS: 1 | US FAERS | |
| 98 | Discomfort | FAERS: 1 | US FAERS | |
| 99 | Disease Progression | FAERS: 1 | US FAERS | |
| 100 | Drug screen false positive | FAERS: 1 | US FAERS | |
| 101 | Drug toxicity | FAERS: 1 | US FAERS | |
| 102 | Emotional distress | FAERS: 1 | US FAERS | |
| 103 | Epilepsy | FAERS: 1 | US FAERS | |
| 104 | Excoriation | FAERS: 1 | US FAERS | |
| 105 | Extraocular Muscle Paresis | FAERS: 1 | US FAERS | |
| 106 | Fatigue | FAERS: 1 | US FAERS | |
| 107 | Feeling jittery | FAERS: 1 | US FAERS | |
| 108 | Flushing | FAERS: 1 | US FAERS | |
| 109 | Gait inability | FAERS: 1 | US FAERS | |
| 110 | Gallbladder pain | FAERS: 1 | US FAERS | |
| 111 | Gangrene | FAERS: 1 | US FAERS | |
| 112 | Gastritis | FAERS: 1 | US FAERS | |
| 113 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 114 | Hypertensive crisis | FAERS: 1 | US FAERS | |
| 115 | Hyperventilation | FAERS: 1 | US FAERS | |
| 116 | Incontinence | FAERS: 1 | US FAERS | |
| 117 | Intentional product misuse | FAERS: 1 | US FAERS | |
| 118 | Lip swelling | FAERS: 1 | US FAERS | |
| 119 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 120 | Mallory-Weiss Syndrome | FAERS: 1 | US FAERS | |
| 121 | Maternal exposure during pregnancy | FAERS: 1 | US FAERS | |
| 122 | Medication residue present | FAERS: 1 | US FAERS | |
| 123 | Muscle tightness | FAERS: 1 | US FAERS | |
| 124 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 125 | Mydriasis | FAERS: 1 | US FAERS | |
| 126 | Myopia | FAERS: 1 | US FAERS | |
| 127 | Nasopharyngitis | FAERS: 1 | US FAERS | |
| 128 | Nocturia | FAERS: 1 | US FAERS | |
| 129 | Osteitis | FAERS: 1 | US FAERS | |
| 130 | Osteomyelitis | FAERS: 1 | US FAERS | |
| 131 | Pancreatic operation | FAERS: 1 | US FAERS | |
| 132 | Pancreatitis | FAERS: 1 | US FAERS | |
| 133 | Paradoxical drug reaction | FAERS: 1 | US FAERS | |
| 134 | Peripheral swelling | FAERS: 1 | US FAERS | |
| 135 | Physical deconditioning | FAERS: 1 | US FAERS | |
| 136 | Polyuria | FAERS: 1 | US FAERS | |
| 137 | Prescription drug used without a prescription | FAERS: 1 | US FAERS | |
| 138 | Prescription form tampering | FAERS: 1 | US FAERS | |
| 139 | Product formulation issue | FAERS: 1 | US FAERS | |
| 140 | Product label issue | FAERS: 1 | US FAERS | |
| 141 | Purpura | FAERS: 1 | US FAERS | |
| 142 | Purulence | FAERS: 1 | US FAERS | |
| 143 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 144 | Restless Legs Syndrome | FAERS: 1 | US FAERS | |
| 145 | Rhinitis | FAERS: 1 | US FAERS | |
| 146 | Shock | FAERS: 1 | US FAERS | |
| 147 | Sleep Talking | FAERS: 1 | US FAERS | |
| 148 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 149 | Tension Headache | FAERS: 1 | US FAERS | |
| 150 | Tinnitus | FAERS: 1 | US FAERS | |
| 151 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 152 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 153 | Visual Impairment | FAERS: 1 | US FAERS | |
| 154 | Weight decreased | FAERS: 1 | US FAERS |
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