MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Enflurane

(JPGQOUSTVILISH-UHFFFAOYSA-N)

Structure

SMILES: FC(OC(C(Cl)F)(F)F)F
Type(s): Approved; Investigational; Vet_approved
ATC code(s): N01AB04
Molecular Formula:: C3H2ClF5O
Molecular Weight:: 184.492
Log P:: 2.3528
Hydrogen Bond Acceptor:: 1
Hydrogen Bond Donor:: 0
TPSA:: 9.23
CAS Number(s):: 13838-16-9

Synonym(s)

Enflurane

Alyrane

Enfran

Enlirane

Ethrane

Etran

External Link(s)

MeSH	D004737
PubChem Compound	3226
ChEBI	4792
CHEMBL	CHEMBL1257
DrugBank	DB00228
DrugCentral	1009
IUPHAR/BPS Guide to PHARMACOLOGY	7175
KEGG	cpd:C07516 dr:D00543
Therapeutic Target Database	D0AO9S

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Acute kidney injury	973714 3476700 4414316	CTD
2	Amnesia	2197898	CTD
3	Anuria	973714	CTD
4	Atrioventricular Block	3605739	CTD
5	Bradycardia	3605739	CTD
6	Carbon dioxide decreased		SIDER
7	Chemical and Drug Induced Liver Injury	View details 3324816 3608133 4036534 6502185 6859708 7161468 9075521 11873055	CTD
8	Chills		SIDER
9	Cholestasis	3608133	CTD
10	Fatty Liver	3324816	CTD
11	Fever	6859708 7426222	CTD
12	Headache	7448613 9689271	CTD
13	Heart Block	7112202	CTD
14	Heart failure	626424	CTD
15	Hepatic necrosis		SIDER
16	Hepatitis	7380208 7426222	CTD
17	Hepatotoxicity		SIDER
18	Hypocapnia		SIDER
19	Hypotension	View details 734652 1874198 2020101 2718706 3383316 3811806 7438608	CTD SIDER
20	Kidney Diseases	736249	CTD
21	Liver diseases	7647582	CTD
22	Muscle Rigidity	8865732	CTD
23	Muscle Spasticity	3674476	CTD
24	Myocardial Ischemia	1824584	CTD
25	Myoclonus	7448613	CTD
26	Myoglobinuria	731274 8865732	CTD
27	Nausea	3146231	CTD SIDER
28	Necrosis	731274 6859708	CTD
29	Oliguria	973714	CTD
30	Polyuria	4414316	CTD
31	Postoperative Complications	View details 1536426 3434767 3789347 7425324	CTD
32	Postoperative Nausea and Vomiting	1535202	CTD
33	Pulmonary function test decreased		SIDER
34	Quadriplegia	2145134	CTD
35	Renal Insufficiency	7425324 7427187	CTD
36	Respiratory Depression		SIDER
37	Respiratory Insufficiency	626424	CTD
38	Rhabdomyolysis	3476700	CTD
39	Seizures	View details 95709 1536426 3276852 3789347 4398198 6153967 6786708 6797329 8055610	CTD
40	Shivering		SIDER
41	Status Asthmaticus	2145134	CTD
42	Substance Withdrawal Syndrome	View details 3777397 6502185 6517256 6696218 7416529	CTD
43	Tachycardia, Ventricular	5922	CTD
44	Tachycardia	8210002	CTD
45	Traumatic liver injury		SIDER
46	Urination Disorders	973714	CTD
47	Vomiting	3146231 9689271	CTD SIDER
48	jaundice	6859708 7425324	CTD

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