MetaADEDB 2.0 @ LMMD
vinflunine
(NMDYYWFGPIMTKO-HBVLKOHWSA-N)
Structure
SMILES
COc1cc2N(C)[C@@H]3[C@@]4(c2cc1[C@]1(C[C@@H]2CN(Cc5c1[nH]c1c5cccc1)C[C@@H](C2)C(F)(F)C)C(=O)OC)CCN1[C@H]4[C@@]([C@H]([C@]3(O)C(=O)OC)OC(=O)C)(CC)C=CC1
Molecular Formula:
C45H54F2N4O8
Molecular Weight:
816.929
Log P:
5.0195
Hydrogen Bond Acceptor:
11
Hydrogen Bond Donor:
2
TPSA:
133.87
CAS Number(s):
162652-95-1
Synonym(s)
1.
vinflunine
2.
Javlor
External Link(s)
MeSHC111217
PubChem Compound6918295
Therapeutic Target DatabaseD0OT9S
ZINC95627889
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal PainOFFSIDES
SIDER
2Abdominal discomfortSIDER
3AbscessSIDER
4AcidosisSIDER
5Acute Coronary SyndromeSIDER
6AgeusiaSIDER
7AgitationSIDER
8Alanine Aminotransferase IncreasedSIDER
9AlopeciaSIDER
10Altered state of consciousnessSIDER
11AnorexiaSIDER
12AnxietySIDER
13ArthralgiaSIDER
14Aspartate Aminotransferase IncreasedSIDER
15AstheniaSIDER
16AtaxiaOFFSIDES
17AuraOFFSIDES
18Back PainSIDER
19Bladder painSIDER
20Blood and lymphatic system disordersSIDER
21Blood sodiumOFFSIDES
22Bone painSIDER
23BronchitisSIDER
24BronchospasmSIDER
25Cancer PainSIDER
26Catheter related infectionSIDER
27Chest PainOFFSIDES
SIDER
28ChillsSIDER
29Colonic Pseudo-ObstructionSIDER
30ConstipationSIDER
31CystitisSIDER
32CystSIDER
33Deep Vein ThrombosisSIDER
34DehydrationSIDER
35Depressed Level of ConsciousnessSIDER
36DermatitisSIDER
37Device related infectionSIDER
38DiplopiaOFFSIDES
39DiscomfortSIDER
40DisorientationSIDER
41Disseminated Intravascular CoagulationSIDER
42DizzinessSIDER
43Dry skinSIDER
44DysgeusiaSIDER
45DyspepsiaSIDER
46DysphoniaSIDER
47DysuriaSIDER
48Ear and labyrinth disordersSIDER
49Early satietySIDER
50Electrocardiogram ST segment abnormalSIDER
51EnterocolitisOFFSIDES
52Epigastric discomfortSIDER
53EpistaxisSIDER
54EructationSIDER
55ErysipelasOFFSIDES
56ErythemaSIDER
57Escherichia sepsisSIDER
58ExtravasationSIDER
59Facial PainSIDER
60FatigueOFFSIDES
SIDER
61Febrile NeutropeniaSIDER
62Febrile bone marrow aplasiaOFFSIDES
63Feeling abnormalSIDER
64Flank PainSIDER
65FlatulenceOFFSIDES
SIDER
66FlushingSIDER
67GastritisSIDER
68Gastrointestinal PainSIDER
69General physical health deteriorationOFFSIDES
70GoutSIDER
71HeadacheSIDER
72HypersensitivitySIDER
73HypersomniaSIDER
74HypotensionSIDER
75HypotrichosisSIDER
76IleusSIDER
77InfectionOFFSIDES
SIDER
78InfestationSIDER
79InflammationSIDER
80Infusion site erythemaSIDER
81Infusion site painOFFSIDES
SIDER
82Infusion site phlebitisSIDER
83Injection Site ReactionSIDER
84Injection site dermatitisSIDER
85Injection site erythemaSIDER
86Injection site hypersensitivitySIDER
87Injection site irritationSIDER
88Injection site painSIDER
89Injection site phlebitisSIDER
90Injection site urticariaSIDER
91Intention tremorOFFSIDES
92Intestinal ObstructionSIDER
93Joint stiffnessSIDER
94Klebsiella sepsisOFFSIDES
95LethargySIDER
96Leukopenia neonatalOFFSIDES
97LeukopeniaSIDER
98MalaiseSIDER
99Malignant HypertensionOFFSIDES
100MalnutritionSIDER
101Mental impairmentOFFSIDES
102Metabolic acidosisOFFSIDES
103Metastatic painSIDER
104Musculoskeletal PainSIDER
105Musculoskeletal chest painSIDER
106Musculoskeletal discomfortSIDER
107Musculoskeletal stiffnessSIDER
108MyalgiaSIDER
109Myocardial InfarctionSIDER
110NasopharyngitisSIDER
111NauseaOFFSIDES
SIDER
112Neck PainSIDER
113NeuralgiaSIDER
114NeuritisSIDER
115NeuropathySIDER
116NeutropeniaSIDER
117Neutropenic colitisOFFSIDES
118Neutropenic infectionOFFSIDES
SIDER
119Neutropenic sepsisOFFSIDES
SIDER
120Night sweatsSIDER
121NocturiaSIDER
122Non-cardiac chest painSIDER
123Oral candidiasisSIDER
124Oral infectionSIDER
125Oral painSIDER
126Pain of skinSIDER
127PainSIDER
128PalpitationsSIDER
129PancreatitisSIDER
130PancytopeniaSIDER
131Pelvic PainSIDER
132Peripheral motor neuropathySIDER
133Pharyngolaryngeal PainOFFSIDES
SIDER
134PhlebitisSIDER
135PneumoniaSIDER
136Posterior reversible encephalopathy syndromeSIDER
137PresyncopeSIDER
138Productive CoughSIDER
139PruritusSIDER
140Pulmonary EmbolismSIDER
141PurpuraSIDER
142PyelonephritisOFFSIDES
SIDER
143QuadriplegiaOFFSIDES
144Renal ColicSIDER
145Respiratory FailureOFFSIDES
146RetchingSIDER
147Risus sardonicusOFFSIDES
148Saliva alteredSIDER
149SepsisSIDER
150Septic ShockOFFSIDES
SIDER
151ShockSIDER
152Sinus TachycardiaSIDER
153Skin lesionSIDER
154StomatitisSIDER
155SubileusOFFSIDES
SIDER
156SyncopeSIDER
157TachycardiaSIDER
158ThrombocytopeniaSIDER
159ThrombophlebitisSIDER
160TinnitusSIDER
161Tongue blisteringSIDER
162ToothacheSIDER
163Transaminases increasedSIDER
164TremorSIDER
165TrismusSIDER
166Ureterostomy site discomfortSIDER
167Urinary tract infectionSIDER
168UrticariaSIDER
169Vascular purpuraSIDER
170VasculitisSIDER
171VasospasmSIDER
172Venous ThrombosisSIDER
173VertigoSIDER
174Visual ImpairmentSIDER
175Visual disturbanceSIDER
176Vitreous floatersSIDER
177VomitingSIDER
178Weight decreasedSIDER
179Wound InfectionSIDER
180nervous system disorderSIDER
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