MetaADEDB 2.0 @ LMMD
Amsacrine
(XCPGHVQEEXUHNC-UHFFFAOYSA-N)
Structure
SMILES
COc1cc(ccc1Nc1c2ccccc2nc2c1cccc2)NS(=O)(=O)C
Type(s)
Approved; Investigational
ATC code(s)
L01XX01
Molecular Formula:
C21H19N3O3S
Molecular Weight:
393.459
Log P:
5.7385
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
2
TPSA:
88.7
CAS Number(s):
51264-14-3
Synonym(s)
1.
Amsacrine
2.
m-AMSA
3.
AMSA
4.
AMSA P-D
5.
Amsacrina
6.
Amsidine
7.
Amsidyl
8.
Cain's Acridine
9.
NSC-141549
10.
NSC-156303
11.
NSC-249992
12.
SN-11841
13.
SN11841
14.
meta-AMSA
15.
AMSA P D
16.
AMSA PD
17.
Cain Acridine
18.
Cains Acridine
19.
NSC 141549
20.
NSC 156303
21.
NSC 249992
22.
NSC141549
23.
NSC156303
24.
NSC249992
25.
SN 11841
26.
meta AMSA
External Link(s)
MeSHD000677
PubChem Compound2179
BindingDB50013444
87351
ChEBI2687
CHEMBLCHEMBL43
DrugBankDB00276
DrugCentral203
KEGGcpd:C01553
dr:D02321
Therapeutic Target DatabaseD0G9YH
ZINC3812923
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal PainSIDER
2Adenocarcinoma7894236CTD
3AgranulocytosisSIDER
4AlopeciaSIDER
5AnorexiaSIDER
6Aspartate Aminotransferase IncreasedSIDER
7AstheniaSIDER
8Atrial FibrillationSIDER
9Blood alkaline phosphatase increasedSIDER
10Blood and lymphatic system disordersSIDER
11Blood creatinine increasedSIDER
12Blood urea increasedSIDER
13Bone Marrow Diseases2410119CTD
14Bone marrow depressionSIDER
15BradycardiaSIDER
16Cardiomyopathies2410119CTD
17Chemical and Drug Induced Liver Injury3463435CTD
18ChromaturiaSIDER
19Creatinine increasedSIDER
20DermatitisSIDER
21Diarrhea2410119CTD
22DizzinessSIDER
23Ejection Fraction DecreasedSIDER
24ExtravasationSIDER
25FatigueSIDER
26Febrile NeutropeniaSIDER
27Feeling abnormalSIDER
28Gastrointestinal Diseases3463435CTD
29Gastrointestinal PainSIDER
30GingivitisSIDER
31HeadacheSIDER
32Hepatic InsufficiencySIDER
33HepatitisSIDER
34HepatotoxicitySIDER
35Hyperbilirubinemia2410119CTD
36HypersensitivitySIDER
37HypotensionSIDER
38InfectionSIDER
39InfestationSIDER
40InflammationSIDER
41Injection Site ReactionSIDER
42Injection site inflammationSIDER
43Intestinal Neoplasms7894236CTD
44LethargySIDER
45LeukopeniaSIDER
46MalnutritionSIDER
47Mood swingsSIDER
48Musculoskeletal PainSIDER
49MyelosuppressionSIDER
50NauseaSIDER
51NecrosisSIDER
52Neoplasms, Multiple Primary7894236CTD
53PainSIDER
54PancytopeniaSIDER
55Perirectal abscessSIDER
56Phlebitis6897887
9295513		CTD
SIDER
57Protein urine presentSIDER
58ProteinuriaSIDER
59PurpuraSIDER
60SepsisSIDER
61Sick Sinus Syndrome1877195CTD
62Sinus TachycardiaSIDER
63Stomatitis2410119CTD
SIDER
64TachycardiaSIDER
65ThrombocytopeniaSIDER
66UrticariaSIDER
67Vascular purpuraSIDER
68Ventricular FibrillationSIDER
69Ventricular arrhythmiaSIDER
70VomitingSIDER
71Weight decreasedSIDER
72jaundiceSIDER
73leukemia3681383
9295513		CTD
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