MetaADEDB 2.0 @ LMMD
Probenecid
(DBABZHXKTCFAPX-UHFFFAOYSA-N)
Structure
SMILES
CCCN(S(=O)(=O)c1ccc(cc1)C(=O)O)CCC
Type(s)
Approved; Investigational
ATC code(s)
G01AE10; M04AB01
Molecular Formula:
C13H19NO4S
Molecular Weight:
285.359
Log P:
3.2763
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
1
TPSA:
83.06
CAS Number(s):
57-66-9
Synonym(s)
1.
Probenecid
2.
Benecid
3.
Benemid
4.
Benuryl
5.
Pro-Cid
6.
Probecid
7.
Probenecid Weimer
External Link(s)
MeSHD011339
PubChem Compound4911
BindingDB50206509
ChEBI8426
CHEMBLCHEMBL897
DrugBankDB01032
DrugCentral2268
IUPHAR/BPS Guide to PHARMACOLOGY4357
KEGGcpd:C07372
dr:D00475
Therapeutic Target DatabaseD0L7FM
ZINC1982
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Nephrotic SyndromeFAERS: 3

View details

5051645
5655316
5667986
6071127
 		CTD
SIDER
US FAERS
2Abdominal discomfortFAERS: 1OFFSIDES
US FAERS
3NauseaFAERS: 19525435CTD
SIDER
US FAERS
4ProteinuriaFAERS: 15655316
5667986
17510101		CTD
US FAERS
5PruritusFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
6Respiratory DepressionFAERS: 1US FAERS
7TremorFAERS: 1US FAERS
8UrticariaFAERS: 1SIDER
US FAERS
9AIDS-Related Opportunistic Infections9525435CTD
10Abdominal PainOFFSIDES
11Accidental overdoseOFFSIDES
12Acid refluxOFFSIDES
13AcidosisOFFSIDES
14Activities of daily living impairedOFFSIDES
15Acute kidney injury5655316
11773481		CTD
16Acute respiratory failureOFFSIDES
17AdenocarcinomaOFFSIDES
18AgraphiaOFFSIDES
19Albuminuria5667986CTD
20AlopeciaSIDER
21AmphetaminesOFFSIDES
22Anaphylactic shockSIDER
23Anastomotic complicationOFFSIDES
24Anemia, Hemolytic4124995
17381629		CTD
25AnhedoniaOFFSIDES
26AnorexiaSIDER
27Anti-SS-A antibody positiveOFFSIDES
28AnxietyOFFSIDES
29AphoniaOFFSIDES
30ArteriosclerosisOFFSIDES
31Arteriovenous fistulaOFFSIDES
32Arthritis, Gouty3701734
5655316		CTD
33Aspiration PneumoniaOFFSIDES
34AstheniaOFFSIDES
35AtaxiaOFFSIDES
36AtelectasisOFFSIDES
37Basal cell carcinomaOFFSIDES
38BedriddenOFFSIDES
39Blood GlucoseOFFSIDES
40Blood albumin decreasedOFFSIDES
41Blood chloride decreasedOFFSIDES
42Blood creatinine increasedOFFSIDES
43Blood glucose decreasedOFFSIDES
44Blood lactate dehydrogenase increasedOFFSIDES
45Blood potassium increasedOFFSIDES
46Blood urea increasedOFFSIDES
47Bone marrow toxicityOFFSIDES
48Bone painOFFSIDES
49Brain natriuretic peptide increasedOFFSIDES
50Brain stem syndromeOFFSIDES
51BronchitisOFFSIDES
52CalcinosisOFFSIDES
53Candida sepsisOFFSIDES
54Cardioactive drug level increasedOFFSIDES
55Catatonia24768735CTD
56Catheter placementOFFSIDES
57Catheter related infectionOFFSIDES
58Cerebral atrophyOFFSIDES
59Chemical and Drug Induced Liver Injury24085192CTD
60Chest PainOFFSIDES
61Choking sensationOFFSIDES
62Chronic Obstructive Airway DiseaseOFFSIDES
63Clostridium colitisOFFSIDES
64ColitisOFFSIDES
65CystOFFSIDES
66Cytomegalovirus Retinitis9525435CTD
67DeafnessOFFSIDES
68DehydrationOFFSIDES
69DemyelinationOFFSIDES
70Depressed Level of ConsciousnessOFFSIDES
71DermatitisSIDER
72Device related infectionOFFSIDES
73DiplopiaOFFSIDES
74DizzinessOFFSIDES
SIDER
75DrowningOFFSIDES
76DyspepsiaCanada Vigilance: 1Canada Vigilance
OFFSIDES
77Economic problemOFFSIDES
78Edema5655316
5667986
17510101		CTD
79Emotional disorderOFFSIDES
80EnuresisOFFSIDES
81Eosinophilia1242194CTD
82EpididymitisOFFSIDES
83Erectile dysfunctionOFFSIDES
84Erosive gastritisOFFSIDES
85Erythema MultiformeSIDER
86Fluid overloadOFFSIDES
87FlushingSIDER
88FormicationOFFSIDES
89GastroenteritisOFFSIDES
90Gastrointestinal Diseases5667986CTD
91GlobulinuriaOFFSIDES
92Glycosuria1673268
2867768		CTD
93Gonorrhea6228024
6271049		CTD
94Gout

View details

1232932
4036870
5667986
8842764
9799074
10920575
17510101
18250112
21629661
23129053
 		CTD
95HeadacheSIDER
96Hematuria1242194CTD
97Hepatic necrosisSIDER
98Hepatitis COFFSIDES
99Hypercholesterolemia5655316
5667986		CTD
100HypersensitivitySIDER
101Hyperuricemia

View details

8842764
17308859
18250112
22865646
 		CTD
102Hypoalbuminemia5655316CTD
103Hypokinesia24768735CTD
104HyporeflexiaOFFSIDES
105HypoxiaOFFSIDES
106Immune reconstitution syndromeOFFSIDES
107Impaired work abilityOFFSIDES
108Increased bronchial secretionOFFSIDES
109Infusion site mobility decreasedOFFSIDES
110Intermittent ClaudicationOFFSIDES
111Intestinal ObstructionOFFSIDES
112IritisOFFSIDES
113JC virus infectionOFFSIDES
114Kidney Diseases

View details

1673268
2867768
3781430
6538115
22865646
 		CTD
115Kidney Failure, Chronic8842764CTD
116Kidney FailureOFFSIDES
117LeukopeniaSIDER
118Limb injuryOFFSIDES
119LipaseOFFSIDES
120Lymphocyte count decreasedOFFSIDES
121Malignant HypertensionOFFSIDES
122Metabolic acidosisOFFSIDES
123Multiple System AtrophyOFFSIDES
124Muscle necrosisOFFSIDES
125Mycosis FungoidesOFFSIDES
126Necrosis3781430
9637657		CTD
127Nerve Degeneration19084578CTD
128Non-cardiac chest painOFFSIDES
129NystagmusOFFSIDES
130Oral pruritusOFFSIDES
131PainOFFSIDES
SIDER
132PancreatitisOFFSIDES
133Parkinson Disease19084578CTD
134Parkinsonian Disorders24768735
25064079		CTD
135Pelvic Inflammatory Disease1173853CTD
136Peripheral arterial occlusive diseaseOFFSIDES
137Pharyngolaryngeal PainOFFSIDES
138Post procedural complicationOFFSIDES
139Pulmonary congestionOFFSIDES
140QRS axis abnormalOFFSIDES
141Renal Colic5667986CTD
SIDER
142Renal tubular disorderOFFSIDES
143Renal tubular necrosisOFFSIDES
144Respiratory FailureOFFSIDES
145Rocky Mountain Spotted FeverOFFSIDES
146SneezingCanada Vigilance: 1Canada Vigilance
147Staphylococcal Infections5560145CTD
148Stevens-Johnson SyndromeSIDER
149Tooth ExtractionOFFSIDES
150Tooth LossOFFSIDES
151Toxic Epidermal NecrolysisSIDER
152UlcerOFFSIDES
153Unresponsive to stimuliOFFSIDES
154Visual disturbanceOFFSIDES
155Vocal Cord ParalysisOFFSIDES
156VomitingCanada Vigilance: 1Canada Vigilance
SIDER
157Wound infection staphylococcalOFFSIDES
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