MetaADEDB 2.0 @ LMMD
Benzbromarone
(WHQCHUCQKNIQEC-UHFFFAOYSA-N)
Structure
SMILES
CCc1oc2c(c1C(=O)c1cc(Br)c(c(c1)Br)O)cccc2
Type(s)
Investigational; Withdrawn
ATC code(s)
M04AB03
Molecular Formula:
C17H12Br2O3
Molecular Weight:
424.083
Log P:
5.4568
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
50.44
CAS Number(s):
3562-84-3; 879713-04-9
Synonym(s)
1.
Benzbromarone
2.
Acifugan
3.
Benzbromaron
4.
Benzbromaron AL
5.
Benzbromaron-Ratiopharm
6.
Besuric
7.
Desuric
8.
Narcaricin
9.
Urinorm
10.
AL, Benzbromaron
11.
Benzbromaron Ratiopharm
External Link(s)
MeSHD001553
PubChem Compound2333
BindingDB50158460
ChEBI3023
CHEMBLCHEMBL388590
DrugBankDB12319
DrugCentral318
KEGGdr:D01056
Therapeutic Target DatabaseD0Z3DY
ZINC608205
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AbasiaOFFSIDES
2Abdominal PainOFFSIDES
3Activities of daily living impairedOFFSIDES
4Alanine Aminotransferase IncreasedOFFSIDES
5Alcohol consumptionOFFSIDES
6AlopeciaOFFSIDES
7Altered state of consciousnessOFFSIDES
8AnorexiaOFFSIDES
9ApathyOFFSIDES
10Arthritis, Gouty17013833CTD
11ArthritisOFFSIDES
12Aspiration PneumoniaOFFSIDES
13AsthmaOFFSIDES
14Autoimmune hepatitisOFFSIDES
15Bacteria sputum identifiedOFFSIDES
16BasophiliaOFFSIDES
17Benign Prostatic HyperplasiaOFFSIDES
18BiopsyOFFSIDES
19Blood Coagulation Disorders19483382CTD
20Blood alkaline phosphatase decreasedOFFSIDES
21Blood amylase increasedOFFSIDES
22Blood creatine phosphokinase increasedOFFSIDES
23Blood creatinine increasedOFFSIDES
24Blood glucose decreasedOFFSIDES
25Blood lactate dehydrogenase increasedOFFSIDES
26Blood phosphorus decreasedOFFSIDES
27Blood potassium increasedOFFSIDES
28Blood sodiumOFFSIDES
29Blood urea increasedOFFSIDES
30Blood uric acidOFFSIDES
31Bronchoalveolar LavageOFFSIDES
32Bulbar palsyOFFSIDES
33Cardioactive drug levelOFFSIDES
34CardiotoxicityOFFSIDES
35Cardiovascular insufficiencyOFFSIDES
36Cerebellar infarctionOFFSIDES
37Chemical and Drug Induced Liver Injury

View details

8014449
15493119
15799034
18020424
19362101
23152190
23956101
24014644
24085192
25108121
25934330
26921665
28437613
31102694
 		CTD
38Completed SuicideOFFSIDES
39Depressed Level of ConsciousnessOFFSIDES
40DiabetesOFFSIDES
41Diabetes mellitus inadequate controlOFFSIDES
42DiarrheaOFFSIDES
43Duodenal perforationOFFSIDES
44DuodenitisOFFSIDES
45DyslaliaOFFSIDES
46End Stage Liver Disease12084041CTD
47Enterococcal infectionOFFSIDES
48EpididymitisOFFSIDES
49Erythema MultiformeOFFSIDES
50ErythropeniaOFFSIDES
51Gamma-Glutamyltransferase IncreasedOFFSIDES
52Gastric adenomaOFFSIDES
53GastroenteritisOFFSIDES
54Gastrointestinal Diseases680625CTD
55Gastrointestinal perforationOFFSIDES
56General physical health deteriorationOFFSIDES
57Genital painOFFSIDES
58Gout

View details

1406482
2080622
2239590
8842764
9439546
9500573
9849314
10920575
10925570
11876034
12209479
15980902
17047891
17223663
17525717
18020424
18250112
18546882
18559233
18633127
19048458
20190479
 		CTD
OFFSIDES
59Hemorrhage20190479CTD
60HemothoraxOFFSIDES
61Hepatic Encephalopathy10845680
12084041		CTD
62Hepatic congestionOFFSIDES
63Hepatomegaly2260096
28108177		CTD
64HepatosplenomegalyOFFSIDES
65Hyperuricemia

View details

1406482
2102029
2239590
7997431
9849314
10845680
12084041
12188443
12209479
12759298
15516011
16234313
16913436
17223663
17308859
18250112
18546882
19933411
20506124
 		CTD
66HypoaldosteronismOFFSIDES
67Kidney FailureOFFSIDES
68Left atrial dilatationOFFSIDES
69Lip erosionOFFSIDES
70Lipodystrophy acquiredOFFSIDES
71Liver Cirrhosis9392688CTD
72Liver Failure, Acute10845680
12084041		CTD
73Lung AbscessOFFSIDES
74Lung consolidationOFFSIDES
75Lymphocyte count decreasedOFFSIDES
76Lymphocytic infiltrationOFFSIDES
77Metabolic acidosisOFFSIDES
78Musculoskeletal stiffnessOFFSIDES
79Myoglobin blood increasedOFFSIDES
80Myoglobin blood presentOFFSIDES
81NasopharyngitisOFFSIDES
82NephrolithiasisOFFSIDES
83Nephrotic SyndromeOFFSIDES
84Neutrophil count decreasedOFFSIDES
85OverdoseOFFSIDES
86PeritonitisOFFSIDES
87Pharyngolaryngeal PainOFFSIDES
88Platelet count normalOFFSIDES
89Productive CoughOFFSIDES
90Psychiatric symptomOFFSIDES
91Pulmonary Eosinophilia20190479CTD
OFFSIDES
92PurulenceOFFSIDES
93PyelonephritisOFFSIDES
94Pyloric StenosisOFFSIDES
95Quality of life decreasedOFFSIDES
96Renal tubular atrophyOFFSIDES
97Renal tubular disorderOFFSIDES
98Residual urineOFFSIDES
99Respiratory FailureOFFSIDES
100RhabdomyolysisOFFSIDES
101Sputum culture positiveOFFSIDES
102Stevens-Johnson SyndromeOFFSIDES
103Tension HeadacheOFFSIDES
104TetanyOFFSIDES
105Thalamic infarctionOFFSIDES
106ThyroiditisOFFSIDES
107Upper respiratory tract inflammationOFFSIDES
108Urate nephropathyOFFSIDES
109Ureteric anastomosis complicationOFFSIDES
110Urobilin urine presentOFFSIDES
111Vascular insufficiencyOFFSIDES
112jaundice10845680CTD
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