MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Cefotiam

(QYQDKDWGWDOFFU-IUODEOHRSA-N)

Structure

SMILES: CN(CCn1nnnc1SCC1=C(C(=O)O)N2[C@H](SC1)[C@@H](C2=O)NC(=O)Cc1csc(n1)N)C
Type(s): Approved; Investigational
ATC code(s): J01DC07
Molecular Formula:: C18H23N9O4S3
Molecular Weight:: 525.628
Log P:: 0.2568
Hydrogen Bond Acceptor:: 16
Hydrogen Bond Donor:: 3
TPSA:: 251.3
CAS Number(s):: 61622-34-2; 66309-69-1; 67356-92-7

Synonym(s)

Cefotiam

Abbott-48999

CGP-14221-E

Cefotiam Hydrochloride

Ceradolan

Haloapor

Halospor

SCE-963

Abbott 48999

10.

Abbott48999

11.

CGP 14221 E

12.

CGP14221E

13.

Hydrochloride, Cefotiam

14.

SCE 963

15.

SCE963

External Link(s)

MeSH	D015310
PubChem Compound	43708
ChEBI	355510
CHEMBL	CHEMBL1296
DrugBank	DB00229
DrugCentral	548
KEGG	cpd:C21544 dr:D07648
Therapeutic Target Database	D0K3DQ
ZINC	3830445

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abdominal Pain	15221158	CTD
2	Abdominal tenderness		OFFSIDES
3	Abnormal vision		OFFSIDES
4	Abscess		OFFSIDES
5	Acute bronchitis		OFFSIDES
6	Acute respiratory failure		OFFSIDES
7	Acute tonsillitis		OFFSIDES
8	Adenosquamous cell lung cancer		OFFSIDES
9	Adrenal insufficiency neonatal		OFFSIDES
10	Alanine Aminotransferase Increased		OFFSIDES
11	Altered state of consciousness		OFFSIDES
12	Anorectal operation		OFFSIDES
13	Aphagia		OFFSIDES
14	Apnea		OFFSIDES
15	Appendicitis		OFFSIDES
16	Aspergillosis		OFFSIDES
17	Aspiration Pneumonia		OFFSIDES
18	Athetosis		OFFSIDES
19	Autoimmune hepatitis		OFFSIDES
20	Automatism		OFFSIDES
21	Bacteria sputum identified		OFFSIDES
22	Bacteria urine identified		OFFSIDES
23	Band neutrophil percentage decreased		OFFSIDES
24	Blood albumin decreased		OFFSIDES
25	Blood alkaline phosphatase increased		OFFSIDES
26	Blood amylase decreased		OFFSIDES
27	Blood brain barrier defect		OFFSIDES
28	Blood cholinesterase decreased		OFFSIDES
29	Blood creatine phosphokinase increased		OFFSIDES
30	Blood immunoglobulin M		OFFSIDES
31	Blood lactate dehydrogenase decreased		OFFSIDES
32	Blood lactate dehydrogenase increased		OFFSIDES
33	Blood potassium increased		OFFSIDES
34	Blood pressure immeasurable		OFFSIDES
35	Blood sodium abnormal		OFFSIDES
36	Bone marrow depression		OFFSIDES
37	Brain Death		OFFSIDES
38	Bronchitis		OFFSIDES
39	Cancer Pain		OFFSIDES
40	Candida sepsis		OFFSIDES
41	Catheter placement		OFFSIDES
42	Catheter related infection		OFFSIDES
43	Cellulitis		OFFSIDES
44	Chemical and Drug Induced Liver Injury	6317911	CTD
45	Chorioamnionitis		OFFSIDES
46	Clamping of blood vessel		OFFSIDES
47	Clostridium difficile colitis		OFFSIDES
48	Cyanosis		OFFSIDES
49	Depressed Level of Consciousness		OFFSIDES
50	Diabetic Nephropathy		OFFSIDES
51	Disease recurrence		OFFSIDES
52	Disseminated Intravascular Coagulation		OFFSIDES
53	Disseminated intravascular coagulation in newborn		OFFSIDES
54	Drug exposure during pregnancy		OFFSIDES
55	Dyspnea	15221158	CTD
56	Dysuria		OFFSIDES
57	Endoscopy abnormal		OFFSIDES
58	Enterococcal infection		OFFSIDES
59	Erythema		OFFSIDES
60	Escherichia sepsis		OFFSIDES
61	Gamma-Glutamyltransferase Increased		OFFSIDES
62	Gastric ulcer		OFFSIDES
63	Gastroenteritis		OFFSIDES
64	Gastrointestinal Diseases	6317911	CTD
65	Gastrointestinal hypomotility		OFFSIDES
66	Gout		OFFSIDES
67	Granulocyte count decreased		OFFSIDES
68	Heart-lung transplant rejection		OFFSIDES
69	Hemiplegia		OFFSIDES
70	Heparin-induced thrombocytopenia		OFFSIDES
71	Hepatitis C		OFFSIDES
72	Hypercapnia	15221158	CTD
73	Hypoxia	15221158	CTD
74	Immunosuppression		OFFSIDES
75	Infection	6317911	CTD OFFSIDES
76	Injection site ulcer		OFFSIDES
77	Intrauterine infection		OFFSIDES
78	Kidney Diseases	6317911	CTD
79	Kidney Failure		OFFSIDES
80	Leukocyte alkaline phosphatase increased		OFFSIDES
81	Leukopenia neonatal		OFFSIDES
82	Lymphocyte count decreased		OFFSIDES
83	Lymphocyte percentage decreased		OFFSIDES
84	Lymphocyte stimulation test positive		OFFSIDES
85	Malignant neoplasm progression		OFFSIDES
86	Mediastinitis		OFFSIDES
87	Megacolon		OFFSIDES
88	Mixed liver injury		OFFSIDES
89	Muscle Cramp	15221158	CTD
90	Muscle necrosis		OFFSIDES
91	Myoclonus	15221158	CTD
92	Nasopharyngitis		OFFSIDES
93	Neutrophil count decreased		OFFSIDES
94	Oculomucocutaneous syndrome		OFFSIDES
95	Oropharyngeal pain		OFFSIDES
96	PCO2 decreased		OFFSIDES
97	PO2 abnormal		OFFSIDES
98	PO2 decreased		OFFSIDES
99	Pancreatic carcinoma recurrent		OFFSIDES
100	Pathogen resistance		OFFSIDES
101	Periodontitis		OFFSIDES
102	Peritonitis		OFFSIDES
103	Peritonsillitis		OFFSIDES
104	Pneumocystis jiroveci pneumonia		OFFSIDES
105	Post procedural complication		OFFSIDES
106	Post procedural swelling		OFFSIDES
107	Postoperative wound complication		OFFSIDES
108	Procedural complication		OFFSIDES
109	Protein total decreased		OFFSIDES
110	Proteinuria	8314287	CTD
111	Psychiatric symptom		OFFSIDES
112	Pyelonephritis		OFFSIDES
113	Respiratory Failure		OFFSIDES
114	Rhabdomyolysis		OFFSIDES
115	Septic Shock		OFFSIDES
116	Skin necrosis		OFFSIDES
117	Staphylococcal Infections	9755831	CTD
118	Stenotrophomonas sepsis		OFFSIDES
119	Steroid withdrawal syndrome		OFFSIDES
120	Stevens-Johnson Syndrome		OFFSIDES
121	Streptococcal Infections	9755831	CTD
122	Stress		OFFSIDES
123	Therapy non-responder		OFFSIDES
124	Tooth Extraction		OFFSIDES
125	Upper respiratory tract inflammation		OFFSIDES
126	prostatitis		OFFSIDES

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