Dimenhydrinate
(NFLLKCVHYJRNRH-UHFFFAOYSA-N)
Structure
- SMILES
- Clc1[nH]c2c(n1)n(C)c(=O)n(c2=O)C.CN(CCOC(c1ccccc1)c1ccccc1)C
- Type(s)
- Approved
- Molecular Formula:
- C24H28ClN5O3
- Molecular Weight:
- 469.964
- Log P:
- 2.9679
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 1
- TPSA:
- 85.15
- CAS Number(s):
- 523-87-5
Synonym(s)
1.
Dimenhydrinate
2.
Diphenhydramine Theoclate
3.
Apo-Dimenhydrinate
4.
Aviomarin
5.
Biodramina
6.
Calm-X
7.
Cinfamar
8.
Contramareo
9.
DMH
10.
Dimen Heumann
11.
Dimen Lichtenstein
12.
Dimetabs
13.
Dinate
14.
Dramamine
15.
Dramanate
16.
Gravol
17.
Marmine
18.
Motion-Aid
19.
Nausicalm
20.
Reisegold
21.
Reisetabletten Lünopharm
22.
Reisetabletten Stada
23.
Reisetabletten-ratiopharm
24.
Rodovan
25.
RubieMen
26.
Superpep
27.
Travel Well
28.
TripTone
29.
Vertigo-Vomex
30.
Vomacur
31.
Vomex A
32.
Vomisin
33.
Wehamine
34.
Apo Dimenhydrinate
35.
Calm X
36.
Heumann, Dimen
37.
Lichtenstein, Dimen
38.
Lünopharm, Reisetabletten
39.
Motion Aid
40.
Reisetabletten ratiopharm
41.
Stada, Reisetabletten
42.
Theoclate, Diphenhydramine
43.
Vertigo Vomex
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Overdose | FAERS: 30 | OFFSIDES US FAERS | |
| 2 | Feeling abnormal | FAERS: 14 | US FAERS | |
| 3 | Incorrect dose administered | FAERS: 14 | US FAERS | |
| 4 | Intentional drug misuse | FAERS: 12 | US FAERS | |
| 5 | Intentional misuse | FAERS: 10 | US FAERS | |
| 6 | Vomiting | FAERS: 10 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 7 | Somnolence | FAERS: 8 Canada Vigilance: 10 | Canada Vigilance SIDER US FAERS | |
| 8 | Drug exposure during pregnancy | FAERS: 7 | US FAERS | |
| 9 | Euphoric mood | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 10 | Depressed Level of Consciousness | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 11 | Malaise | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 12 | Medication Error | FAERS: 5 | US FAERS | |
| 13 | Accidental exposure | FAERS: 4 | US FAERS | |
| 14 | Dizziness | FAERS: 4 Canada Vigilance: 6 | Canada Vigilance SIDER US FAERS | |
| 15 | Drug abuse | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | Stevens-Johnson Syndrome | FAERS: 4 | US FAERS | |
| 17 | Accidental overdose | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 18 | Drug Dependence | FAERS: 3 | US FAERS | |
| 19 | Hypersensitivity | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 20 | Memory impairment | FAERS: 3 | US FAERS | |
| 21 | Accidental drug intake by child | FAERS: 2 | US FAERS | |
| 22 | Delusional perception | FAERS: 2 | US FAERS | |
| 23 | Disorientation | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 24 | Drug ineffective | FAERS: 2 | US FAERS | |
| 25 | Fatigue | FAERS: 2 | SIDER US FAERS | |
| 26 | Gastroschisis | FAERS: 2 | US FAERS | |
| 27 | Lip swelling | FAERS: 2 | US FAERS | |
| 28 | Mydriasis | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 29 | Nausea | FAERS: 2 Canada Vigilance: 8 | Canada Vigilance OFFSIDES US FAERS | |
| 30 | Poor quality drug administered | FAERS: 2 | US FAERS | |
| 31 | Pruritus | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 32 | Tremor | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 33 | Unevaluable event | FAERS: 2 | OFFSIDES US FAERS | |
| 34 | Urticaria | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 35 | Abdominal Pain | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 36 | Abdominal discomfort | FAERS: 1 | US FAERS | |
| 37 | Adverse event | FAERS: 1 | US FAERS | |
| 38 | Agitation | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance SIDER US FAERS | |
| 39 | Amnesia | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 40 | Anxiety | FAERS: 1 | US FAERS | |
| 41 | Asthenia | FAERS: 1 | US FAERS | |
| 42 | Asthma | FAERS: 1 | US FAERS | |
| 43 | Chest discomfort | FAERS: 1 | US FAERS | |
| 44 | Choking | FAERS: 1 | US FAERS | |
| 45 | Congenital diaphragmatic hernia | FAERS: 1 | US FAERS | |
| 46 | Crying | FAERS: 1 | US FAERS | |
| 47 | Delirium | FAERS: 1 | US FAERS | |
| 48 | Dependence | FAERS: 1 | US FAERS | |
| 49 | Discomfort | FAERS: 1 | US FAERS | |
| 50 | Drooling | FAERS: 1 | US FAERS | |
| 51 | Drug toxicity | FAERS: 1 | US FAERS | |
| 52 | Drug withdrawal syndrome | FAERS: 1 | US FAERS | |
| 53 | Dysuria | FAERS: 1 | SIDER US FAERS | |
| 54 | Epilepsy | FAERS: 1 | 18382986 | CTD US FAERS |
| 55 | Exposure during breast feeding | FAERS: 1 | US FAERS | |
| 56 | Feeling jittery | FAERS: 1 | US FAERS | |
| 57 | Frustration | FAERS: 1 | US FAERS | |
| 58 | Guillain-Barre Syndrome | FAERS: 1 | US FAERS | |
| 59 | Headache | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance SIDER US FAERS | |
| 60 | Hepatitis C | FAERS: 1 | US FAERS | |
| 61 | Hypersomnia | FAERS: 1 | US FAERS | |
| 62 | Impaired driving ability | FAERS: 1 | US FAERS | |
| 63 | Inappropriate affect | FAERS: 1 | US FAERS | |
| 64 | Influenza | FAERS: 1 | US FAERS | |
| 65 | Intentional product misuse | FAERS: 1 | US FAERS | |
| 66 | Intentional self-injury | FAERS: 1 | US FAERS | |
| 67 | Intercepted medication error | FAERS: 1 | US FAERS | |
| 68 | Mental status changes | FAERS: 1 | US FAERS | |
| 69 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 70 | Mutism | FAERS: 1 | US FAERS | |
| 71 | Nervousness | FAERS: 1 | SIDER US FAERS | |
| 72 | Oropharyngeal swelling | FAERS: 1 | US FAERS | |
| 73 | Pain | FAERS: 1 | US FAERS | |
| 74 | Paranoia | FAERS: 1 | US FAERS | |
| 75 | Protein S Deficiency | FAERS: 1 | US FAERS | |
| 76 | Skin Ulcer | FAERS: 1 | US FAERS | |
| 77 | Sleep Talking | FAERS: 1 | US FAERS | |
| 78 | Tachycardia | FAERS: 1 Canada Vigilance: 3 | 9215510 | CTD SIDER Canada Vigilance US FAERS |
| 79 | Throat irritation | FAERS: 1 | US FAERS | |
| 80 | Toxic Epidermal Necrolysis | FAERS: 1 | US FAERS | |
| 81 | Vertigo | FAERS: 1 | 12189776 15262457 | CTD US FAERS |
| 82 | Abnormal vision | OFFSIDES | ||
| 83 | Accidental exposure to product by child | Canada Vigilance: 1 | Canada Vigilance | |
| 84 | Adenocarcinoma | OFFSIDES | ||
| 85 | Alopecia | OFFSIDES | ||
| 86 | Ammonia increased | OFFSIDES | ||
| 87 | Amniotic Band Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Ankylosing spondylitis | OFFSIDES | ||
| 89 | Anorectal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 90 | Anorexia Nervosa | Canada Vigilance: 1 | Canada Vigilance | |
| 91 | Anorexia | OFFSIDES SIDER | ||
| 92 | Anticholinergic Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 93 | Antidepressant drug clearance decreased | OFFSIDES | ||
| 94 | Anxiety Disorders | 12409990 | CTD | |
| 95 | Apathy | OFFSIDES | ||
| 96 | Artificial anus | OFFSIDES | ||
| 97 | Ascites | OFFSIDES | ||
| 98 | Aspiration Pneumonia | OFFSIDES | ||
| 99 | Ataxia | Canada Vigilance: 1 | 9215510 | CTD Canada Vigilance |
| 100 | Atelectasis | OFFSIDES | ||
| 101 | Aura | OFFSIDES | ||
| 102 | Blood albumin decreased | OFFSIDES | ||
| 103 | Blood amylase increased | OFFSIDES | ||
| 104 | Blood creatine phosphokinase increased | OFFSIDES | ||
| 105 | Blood lactate dehydrogenase increased | OFFSIDES | ||
| 106 | Blood sodium | OFFSIDES | ||
| 107 | Bone pain | OFFSIDES | ||
| 108 | Bradycardia | Canada Vigilance: 2 | Canada Vigilance | |
| 109 | Bronchopleural Fistula | OFFSIDES | ||
| 110 | Bronchopneumonia | OFFSIDES | ||
| 111 | Bronchospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 112 | Burning sensation | Canada Vigilance: 2 | Canada Vigilance | |
| 113 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 114 | Chronic left ventricular failure | OFFSIDES | ||
| 115 | Cirrhosis | OFFSIDES | ||
| 116 | Completed Suicide | Canada Vigilance: 1 | Canada Vigilance | |
| 117 | Confabulation | OFFSIDES | ||
| 118 | Confusion | 9215510 | CTD | |
| 119 | Congenital intestinal malformation | Canada Vigilance: 1 | Canada Vigilance | |
| 120 | Cytokine Release Syndrome | OFFSIDES | ||
| 121 | Dehydration | OFFSIDES | ||
| 122 | Dermatitis | SIDER | ||
| 123 | Diplopia | Canada Vigilance: 1 | Canada Vigilance | |
| 124 | Disease Progression | OFFSIDES | ||
| 125 | Disorders of Excessive Somnolence | 1474173 12189776 | CTD | |
| 126 | Disseminated Intravascular Coagulation | OFFSIDES | ||
| 127 | Drowsiness | SIDER | ||
| 128 | Drug addict | OFFSIDES | ||
| 129 | Drug exposure via breast milk | OFFSIDES | ||
| 130 | Drug level increased | Canada Vigilance: 1 | Canada Vigilance | |
| 131 | Duodenal atresia | Canada Vigilance: 1 | Canada Vigilance | |
| 132 | Dysarthria | Canada Vigilance: 1 | Canada Vigilance | |
| 133 | Dysgeusia | Canada Vigilance: 1 | Canada Vigilance | |
| 134 | Dyspepsia | SIDER | ||
| 135 | Ejection Fraction Decreased | OFFSIDES | ||
| 136 | Engraftment syndrome | OFFSIDES | ||
| 137 | Enzyme abnormality | OFFSIDES | ||
| 138 | Epigastric distress | SIDER | ||
| 139 | Erythema Multiforme | Canada Vigilance: 1 | Canada Vigilance | |
| 140 | Erythema | Canada Vigilance: 3 | Canada Vigilance | |
| 141 | Febrile Neutropenia | OFFSIDES | ||
| 142 | Flushing | Canada Vigilance: 4 | Canada Vigilance | |
| 143 | Foreign body aspiration | OFFSIDES | ||
| 144 | Gastroenteritis | OFFSIDES | ||
| 145 | General physical health deterioration | OFFSIDES | ||
| 146 | Genital Herpes | OFFSIDES | ||
| 147 | Glossitis | Canada Vigilance: 1 | Canada Vigilance | |
| 148 | Granuloma | OFFSIDES | ||
| 149 | Hallucinations | 5058102 9215510 | CTD | |
| 150 | Hepatitis | OFFSIDES | ||
| 151 | Hepatotoxicity | OFFSIDES | ||
| 152 | Human herpes virus 6 serology positive | OFFSIDES | ||
| 153 | Hypospadias | Canada Vigilance: 1 | Canada Vigilance | |
| 154 | Hypotension | Canada Vigilance: 1 | Canada Vigilance | |
| 155 | Infection | OFFSIDES | ||
| 156 | Injection Site Reaction | Canada Vigilance: 5 | Canada Vigilance | |
| 157 | Injection site bruising | Canada Vigilance: 1 | Canada Vigilance | |
| 158 | Injection site erythema | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 159 | Injection site pain | Canada Vigilance: 1 | Canada Vigilance | |
| 160 | Lassitude | SIDER | ||
| 161 | Lethargy | Canada Vigilance: 2 | 5058102 | CTD Canada Vigilance |
| 162 | Leukopenia neonatal | OFFSIDES | ||
| 163 | Long QT Syndrome | OFFSIDES | ||
| 164 | Lung consolidation | OFFSIDES | ||
| 165 | Lymphocele | OFFSIDES | ||
| 166 | Medication residue | OFFSIDES | ||
| 167 | Muscle Fatigue | OFFSIDES | ||
| 168 | Muscle Spasticity | Canada Vigilance: 1 | Canada Vigilance | |
| 169 | Muscle Weakness | OFFSIDES | ||
| 170 | Myoclonus | Canada Vigilance: 1 | Canada Vigilance | |
| 171 | Nervous tension | OFFSIDES | ||
| 172 | Ocular Motility Disorders | 12189776 | CTD | |
| 173 | Oliguria | Canada Vigilance: 1 | Canada Vigilance | |
| 174 | Opisthotonus | Canada Vigilance: 1 | Canada Vigilance | |
| 175 | Pallor | Canada Vigilance: 2 | Canada Vigilance | |
| 176 | Palpitations | Canada Vigilance: 1 | Canada Vigilance | |
| 177 | Pericardial effusion | OFFSIDES | ||
| 178 | Phlebitis | Canada Vigilance: 2 | Canada Vigilance | |
| 179 | Plasmacytoma | OFFSIDES | ||
| 180 | Pneumothorax | OFFSIDES | ||
| 181 | Postoperative Nausea and Vomiting | 15721732 | CTD | |
| 182 | Prostatectomy | OFFSIDES | ||
| 183 | Protein total decreased | OFFSIDES | ||
| 184 | Pulmonary sepsis | OFFSIDES | ||
| 185 | Rales | OFFSIDES | ||
| 186 | Rash erythematous | Canada Vigilance: 2 | Canada Vigilance | |
| 187 | Renal tubular disorder | OFFSIDES | ||
| 188 | Renal tubular necrosis | OFFSIDES | ||
| 189 | Respiratory Failure | OFFSIDES | ||
| 190 | Respiratory depth decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 191 | Restlessness | Canada Vigilance: 1 | Canada Vigilance | |
| 192 | Rhabdomyolysis | OFFSIDES | ||
| 193 | Sagittal Sinus Thrombosis | 18382986 | CTD | |
| 194 | Silent myocardial infarction | OFFSIDES | ||
| 195 | Speech Disorders | 9215510 | CTD | |
| 196 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 197 | Subcutaneous Abscess | OFFSIDES | ||
| 198 | Subcutaneous Emphysema | OFFSIDES | ||
| 199 | Substance-Related Disorders | 8467436 | CTD | |
| 200 | Suicide attempt | Canada Vigilance: 1 | Canada Vigilance | |
| 201 | Sweating, Gustatory | 12189776 | CTD | |
| 202 | Tachycardia, Ventricular | 20204717 | CTD | |
| 203 | Tension | SIDER | ||
| 204 | Tinnitus | Canada Vigilance: 1 | Canada Vigilance | |
| 205 | Tracheitis | OFFSIDES | ||
| 206 | Urinary Retention | Canada Vigilance: 1 | Canada Vigilance | |
| 207 | Vasculitis | Canada Vigilance: 1 | Canada Vigilance | |
| 208 | Vein collapse | Canada Vigilance: 1 | Canada Vigilance | |
| 209 | Vestibular Diseases | 15262457 | CTD | |
| 210 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 211 | Xerostomia | 5058102 | CTD |
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