MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

loxoprofen

(YMBXTVYHTMGZDW-UHFFFAOYSA-N)

Structure

SMILES: OC(=O)C(c1ccc(cc1)CC1CCCC1=O)C
Type(s): Investigational
Molecular Formula:: C15H18O3
Molecular Weight:: 246.302
Log P:: 2.7864
Hydrogen Bond Acceptor:: 3
Hydrogen Bond Donor:: 1
TPSA:: 54.37
CAS Number(s):: 68767-14-6

Synonym(s)

loxoprofen

156-S

2-(4-((2-oxocyclopentyl)methyl)phenyl)propionic acid

2-OCPPP

CS 600

CS-600

loxoprofen alcohol

loxoprofen sodium dihydrate

loxoprofen sodium, (R*,S*)-isomer

10.

sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate

11.

sodium loxoprofen

External Link(s)

MeSH	C040656
PubChem Compound	3965
BindingDB	50140320
ChEBI	76172
CHEMBL	CHEMBL19299
DrugBank	DB09212
DrugCentral	1615
KEGG	dr:D08149

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Abdominal Pain		OFFSIDES
2	Acidosis		OFFSIDES
3	Acne		OFFSIDES
4	Acute respiratory failure		OFFSIDES
5	Alanine Aminotransferase Increased		OFFSIDES
6	Alopecia		OFFSIDES
7	Altered state of consciousness		OFFSIDES
8	Anal abscess		OFFSIDES
9	Anorexia		OFFSIDES
10	Anuria		OFFSIDES
11	Apathy		OFFSIDES
12	Aphthous Stomatitis		OFFSIDES
13	Apraxias	12366638	CTD
14	Arteriovenous fistula		OFFSIDES
15	Arthritis	24152722	CTD
16	Ascites		OFFSIDES
17	Aseptic Meningitis		OFFSIDES
18	Aspiration Pneumonia		OFFSIDES
19	Autoimmune hepatitis		OFFSIDES
20	Automatism		OFFSIDES
21	Back Pain	12366638	CTD
22	Bladder cancer recurrent		OFFSIDES
23	Blood albumin decreased		OFFSIDES
24	Blood alkaline phosphatase increased		OFFSIDES
25	Blood amylase increased		OFFSIDES
26	Blood beta-D-glucan increased		OFFSIDES
27	Blood creatinine increased		OFFSIDES
28	Blood immunoglobulin E		OFFSIDES
29	Blood lactate dehydrogenase decreased		OFFSIDES
30	Blood lactate dehydrogenase increased		OFFSIDES
31	Blood magnesium decreased		OFFSIDES
32	Blood pH decreased		OFFSIDES
33	Blood potassium increased		OFFSIDES
34	Blood urea increased		OFFSIDES
35	Blood uric acid		OFFSIDES
36	Body Temperature		OFFSIDES
37	Bone marrow depression		OFFSIDES
38	Bradycardia		OFFSIDES
39	Brain Contusion		OFFSIDES
40	Cancer Pain		OFFSIDES
41	Candida pneumonia		OFFSIDES
42	Cardiomyopathies	16634537	CTD
43	Cataract		OFFSIDES
44	Cervical myelopathy		OFFSIDES
45	Clostridium colitis		OFFSIDES
46	Cognition Disorders	12366638	CTD
47	Cold sweat		OFFSIDES
48	Colon adenoma		OFFSIDES
49	Concomitant disease progression		OFFSIDES
50	Contralateral breast cancer		OFFSIDES
51	Corneal epithelium disorder		OFFSIDES
52	Coronary angioplasty		OFFSIDES
53	Craniotomy		OFFSIDES
54	Cubital Tunnel Syndrome		OFFSIDES
55	Cytomegalovirus test positive		OFFSIDES
56	Depressed Level of Consciousness		OFFSIDES
57	Diabetes		OFFSIDES
58	Disease Progression		OFFSIDES
59	Disseminated Intravascular Coagulation		OFFSIDES
60	Drowsiness		OFFSIDES
61	Dry skin		OFFSIDES
62	Dysgeusia		OFFSIDES
63	Eczema		OFFSIDES
64	Electrocardiogram ST-T segment abnormal		OFFSIDES
65	Encephalitis		OFFSIDES
66	Endoscopy abnormal		OFFSIDES
67	Enterocolitis		OFFSIDES
68	Epididymitis		OFFSIDES
69	Epstein-Barr virus associated lymphoproliferative disorder		OFFSIDES
70	Erythema Multiforme		OFFSIDES
71	Extremity necrosis		OFFSIDES
72	Eyelids pruritus		OFFSIDES
73	Gamma-Glutamyltransferase Increased		OFFSIDES
74	Gastric Antral Vascular Ectasia		OFFSIDES
75	Gastric ulcer		OFFSIDES
76	Gastrointestinal mucosal disorder		OFFSIDES
77	Gastrointestinal perforation		OFFSIDES
78	Gingival erythema		OFFSIDES
79	Glioblastoma Multiforme		OFFSIDES
80	Granuloma		OFFSIDES
81	Hemiplegia		OFFSIDES
82	Hepatitis B positive		OFFSIDES
83	Hepatosplenomegaly		OFFSIDES
84	Herpes simplex serology positive		OFFSIDES
85	Histiocytosis haematophagic		OFFSIDES
86	Hordeolum		OFFSIDES
87	Hypokinesia		OFFSIDES
88	Hypoxia		OFFSIDES
89	Ileal ulcer		OFFSIDES
90	Infected epidermal cyst		OFFSIDES
91	Injection site erythema		OFFSIDES
92	Intestinal Obstruction		OFFSIDES
93	Left Ventricular Hypertrophy		OFFSIDES
94	Leukopenia neonatal		OFFSIDES
95	Lipase		OFFSIDES
96	Lipodystrophy acquired		OFFSIDES
97	Long QT Syndrome		OFFSIDES
98	Lung Abscess		OFFSIDES
99	Lymphocyte count decreased		OFFSIDES
100	Lymphocyte stimulation test positive		OFFSIDES
101	Malignant neoplasm progression		OFFSIDES
102	Metabolic acidosis		OFFSIDES
103	Multiple drug overdose intentional		OFFSIDES
104	Multiple sclerosis relapse		OFFSIDES
105	Myelitis		OFFSIDES
106	Myoglobin blood present		OFFSIDES
107	Myringitis		OFFSIDES
108	Nasopharyngitis		OFFSIDES
109	Nephrotic Syndrome		OFFSIDES
110	Neurological examination abnormal		OFFSIDES
111	Neuromyelitis Optica		OFFSIDES
112	Neutrophil count decreased		OFFSIDES
113	Oliguria		OFFSIDES
114	Oropharyngeal discomfort		OFFSIDES
115	Osteomyelitis		OFFSIDES
116	Pain	16508151	CTD
117	Paraplegia		OFFSIDES
118	Percutaneous Coronary Intervention		OFFSIDES
119	Periarthritis		OFFSIDES
120	Peritonitis		OFFSIDES
121	Pharyngolaryngeal discomfort		OFFSIDES
122	Pleocytosis		OFFSIDES
123	Pleural Infection		OFFSIDES
124	Pleurisy		OFFSIDES
125	Poriomania		OFFSIDES
126	Post procedural infection		OFFSIDES
127	Productive Cough		OFFSIDES
128	Protein total decreased		OFFSIDES
129	Psychiatric symptom		OFFSIDES
130	Pulmonary Hypertension		OFFSIDES
131	Pulmonary Infarction		OFFSIDES
132	Purulent discharge		OFFSIDES
133	Pyoderma Gangrenosum		OFFSIDES
134	Radiation Pneumonitis		OFFSIDES
135	Renal tubular disorder		OFFSIDES
136	Renal tubular necrosis		OFFSIDES
137	Residual urine		OFFSIDES
138	Respiratory Failure		OFFSIDES
139	Rhabdomyolysis		OFFSIDES
140	Seizures	16634537	CTD
141	Shunt malfunction		OFFSIDES
142	Sick Sinus Syndrome		OFFSIDES
143	Sinoatrial Block		OFFSIDES
144	Sinus bradycardia		OFFSIDES
145	Skin test positive		OFFSIDES
146	Splenic neoplasm malignancy unspecified		OFFSIDES
147	Sputum retention		OFFSIDES
148	Stevens-Johnson Syndrome		OFFSIDES
149	Sudden death		OFFSIDES
150	Sympathicotonia		OFFSIDES
151	Tetany		OFFSIDES
152	Troponin T		OFFSIDES
153	Unresponsive to verbal stimuli		OFFSIDES
154	Upper respiratory tract inflammation		OFFSIDES
155	Uterine Cancer		OFFSIDES
156	Vocal Cord Paralysis		OFFSIDES
157	intensive care		OFFSIDES

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120329