MetaADEDB 2.0 @ LMMD
Tropisetron
(ZNRGQMMCGHDTEI-FUNVUKJBSA-N)
Structure
SMILES
CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)c1c[nH]c2c1cccc2
Type(s)
Approved; Investigational
ATC code(s)
A04AA03
Molecular Formula:
C17H20N2O2
Molecular Weight:
284.353
Log P:
2.8878
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
45.33
CAS Number(s):
89565-68-4
Synonym(s)
1.
Tropisetron
2.
(3 alpha-Tropanyl)-1H-indole-3-carboxylic Acid Ester
3.
ICS 205-930
4.
ICS-205-930
5.
ICS-205930
6.
Indole-3-carboxylic Acid Tropine Ester
7.
Navoban
8.
Tropisetron Hydrochloride
9.
ICS 205 930
10.
ICS 205930
11.
Indole 3 carboxylic Acid Tropine Ester
External Link(s)
MeSHD000077526
PubChem Compound656665
BindingDB50108392
ChEBI94647
32269
CHEMBLCHEMBL56564
DrugBankDB11699
DrugCentral2775
IUPHAR/BPS Guide to PHARMACOLOGY260
KEGGcpd:C13666
dr:D02130
Therapeutic Target DatabaseD0K0KH
ZINC100023360
18130447
100019233
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal PainOFFSIDES
SIDER
2Activities of daily living impairedOFFSIDES
3Acute prerenal failureOFFSIDES
4AgraphiaOFFSIDES
5Alanine Aminotransferase IncreasedOFFSIDES
6Alopecia24374478CTD
7Altered state of consciousnessOFFSIDES
8Amnesia1775428CTD
9Anaphylactic shockSIDER
10Anaplastic astrocytomaOFFSIDES
11Angle Closure GlaucomaOFFSIDES
12AnorexiaSIDER
13AscitesOFFSIDES
14AstheniaSIDER
15Autonomic neuropathyOFFSIDES
16Axonal neuropathyOFFSIDES
17Basal Ganglia Diseases11869410CTD
18Bile Duct StenosisOFFSIDES
19BlepharospasmOFFSIDES
20Blood magnesium increasedOFFSIDES
21Blood sodiumOFFSIDES
22BradycardiaSIDER
23Brain DeathOFFSIDES
24Bronchoalveolar LavageOFFSIDES
25BronchospasmSIDER
26Catalepsy2250574CTD
27Cerebral atrophyOFFSIDES
28Chest PainSIDER
29Chest discomfortSIDER
30ChillsSIDER
31Choking sensationOFFSIDES
32CholecystitisOFFSIDES
33CirrhosisOFFSIDES
34Colitis25837923CTD
OFFSIDES
35Congenital tricuspid valve incompetenceOFFSIDES
36Constipation9646236
10089087		CTD
SIDER
37Cytomegalovirus testOFFSIDES
38DermatitisSIDER
39Diarrhea17530482CTD
40Dizziness9544829
17530482		CTD
SIDER
41EndocarditisOFFSIDES
42Endotoxic shockOFFSIDES
43ErythemaSIDER
44FatigueSIDER
45Fatty LiverOFFSIDES
46Febrile NeutropeniaOFFSIDES
47Femoral artery occlusionOFFSIDES
48FlushingSIDER
49Gait Disorders, Neurologic24374478CTD
50Gamma-glutamyltransferase abnormalOFFSIDES
51Gastrointestinal PainSIDER
52General physical health deteriorationOFFSIDES
53Generalized urticariaSIDER
54Glioblastoma MultiformeOFFSIDES
55GranulocytosisOFFSIDES
56Headache9646236
10089087
17530482		CTD
SIDER
57HemiplegiaOFFSIDES
58Hepatic artery occlusionOFFSIDES
59HydrocephalusOFFSIDES
60HypersensitivitySIDER
61HypokinesiaOFFSIDES
62HypotensionSIDER
63Kidney FailureOFFSIDES
64LaryngospasmOFFSIDES
65Leukopenia neonatalOFFSIDES
66Liver diseases23285267CTD
67Nausea

View details

9646236
10089087
17530482
20197557
 		CTD
OFFSIDES
68NeuralgiaOFFSIDES
69Neuropathic painOFFSIDES
70Neutropenic colitisOFFSIDES
71Neutrophil count decreasedOFFSIDES
72PallorOFFSIDES
73PancreatitisOFFSIDES
74Pericardial effusionOFFSIDES
75Perinephric collectionOFFSIDES
76Peripheral embolismOFFSIDES
77Postoperative Nausea and Vomiting12165828CTD
78PriapismOFFSIDES
79Psychotic Disorders11869410CTD
80Pulmonary HypertensionOFFSIDES
81Pulmonary thrombosisOFFSIDES
82Red blood cell schistocytes presentOFFSIDES
83Respiratory FailureOFFSIDES
84Septic ShockOFFSIDES
85ShiveringSIDER
86ShockSIDER
87SomnolenceSIDER
88Sputum culture positiveOFFSIDES
89Staphylococcal Scalded Skin SyndromeOFFSIDES
90SubileusOFFSIDES
91SyncopeSIDER
92TonsillitisOFFSIDES
93Troponin TOFFSIDES
94UrticariaSIDER
95Vomiting

View details

9113122
9544829
9646236
10089087
17530482
20197557
21075553
 		CTD
96nervous system disorderSIDER
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