MetaADEDB 2.0 @ LMMD
brotizolam
(UMSGKTJDUHERQW-UHFFFAOYSA-N)
Structure
SMILES
Brc1cc2c(s1)n1c(CN=C2c2ccccc2Cl)nnc1C
Type(s)
Investigational; Withdrawn
ATC code(s)
N05CD09
Molecular Formula:
C15H10BrClN4S
Molecular Weight:
393.689
Log P:
3.8397
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
0
TPSA:
71.31
CAS Number(s):
57801-81-7
Synonym(s)
1.
brotizolam
2.
Lendorm
3.
Lendormin
4.
Lindormin
5.
Sintonal
6.
We 941
External Link(s)
MeSHC020960
PubChem Compound2451
BindingDB50011875
ChEBI31308
CHEMBLCHEMBL32479
DrugBankDB09017
DrugCentral409
KEGGdr:D01744
ZINC2570830
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal symptomOFFSIDES
2AbuseOFFSIDES
3AcneOFFSIDES
4Activation syndromeOFFSIDES
5Alanine Aminotransferase IncreasedOFFSIDES
6Alcohol IntoleranceOFFSIDES
7Alcoholic IntoxicationOFFSIDES
8Altered state of consciousnessOFFSIDES
9AlveolitisOFFSIDES
10Ammonia increasedOFFSIDES
11AnorexiaOFFSIDES
12AnuriaOFFSIDES
13ApathyOFFSIDES
14ArteritisOFFSIDES
15AscitesOFFSIDES
16Aspiration PneumoniaOFFSIDES
17Band neutrophil percentage decreasedOFFSIDES
18Band neutrophil percentage increasedOFFSIDES
19Basophil percentage increasedOFFSIDES
20Biliary tract infectionOFFSIDES
21Bladder cancer recurrentOFFSIDES
22Blood albumin decreasedOFFSIDES
23Blood albumin increasedOFFSIDES
24Blood alkaline phosphatase increasedOFFSIDES
25Blood amylase decreasedOFFSIDES
26Blood beta-D-glucan increasedOFFSIDES
27Blood chloride decreasedOFFSIDES
28Blood cholinesterase decreasedOFFSIDES
29Blood creatine phosphokinase increasedOFFSIDES
30Blood creatinine increasedOFFSIDES
31Blood glucose decreasedOFFSIDES
32Blood lactate dehydrogenase increasedOFFSIDES
33Blood osmolarity decreasedOFFSIDES
34Blood phosphorus decreasedOFFSIDES
35Blood potassium decreasedOFFSIDES
36Blood potassium increasedOFFSIDES
37Blood sodium increasedOFFSIDES
38Blood sodiumOFFSIDES
39Blood urea increasedOFFSIDES
40Blood uric acid decreasedOFFSIDES
41Blood uric acidOFFSIDES
42Blood urine presentOFFSIDES
43Buccal mucosal rougheningOFFSIDES
44Bulbar palsyOFFSIDES
45Candida sepsisOFFSIDES
46Cardiac function test abnormalOFFSIDES
47CataractOFFSIDES
48CatatoniaOFFSIDES
49Cerebral artery stenosisOFFSIDES
50CholangiolitisOFFSIDES
51CholecystitisOFFSIDES
52CraniotomyOFFSIDES
53Cytomegalovirus chorioretinitisOFFSIDES
54DehydrationOFFSIDES
55Depressed Level of ConsciousnessOFFSIDES
56Diabetes InsipidusOFFSIDES
57DiarrheaOFFSIDES
58Disseminated Intravascular CoagulationOFFSIDES
59DrowsinessOFFSIDES
60Electrocardiogram changeOFFSIDES
61Enterocolitis bacterialOFFSIDES
62EnterocolitisOFFSIDES
63Eosinophil percentage increasedOFFSIDES
64EpilepsyOFFSIDES
65Erosive gastritisOFFSIDES
66Escherichia infectionOFFSIDES
67Eyelid Function DisorderOFFSIDES
68Food PoisoningOFFSIDES
69Gamma-Glutamyltransferase IncreasedOFFSIDES
70GangreneOFFSIDES
71GastroduodenitisOFFSIDES
72Gastrointestinal hypomotilityOFFSIDES
73Gastrointestinal motility disorderOFFSIDES
74General nutrition disorderOFFSIDES
75Gingival HyperplasiaOFFSIDES
76Grip strengthOFFSIDES
77Hepatic congestionOFFSIDES
78Hepatitis C antibody positiveOFFSIDES
79Histiocytosis haematophagicOFFSIDES
80HyperventilationOFFSIDES
81HypochondriasisOFFSIDES
82HypomaniaOFFSIDES
83HypoxiaOFFSIDES
84ImmunosuppressionOFFSIDES
85ImpetigoOFFSIDES
86Intentional self-injuryOFFSIDES
87Intracardiac massOFFSIDES
88Leukopenia neonatalOFFSIDES
89Lip erosionOFFSIDES
90Liver AbscessOFFSIDES
91Lymphocyte count decreasedOFFSIDES
92Lymphocyte percentage decreasedOFFSIDES
93Malignant neoplasm progressionOFFSIDES
94Monocyte percentage decreasedOFFSIDES
95Multiple drug overdose intentionalOFFSIDES
96Musculoskeletal stiffnessOFFSIDES
97MyringitisOFFSIDES
98NasopharyngitisOFFSIDES
99Nerve BlockOFFSIDES
100Neuroleptic Malignant SyndromeOFFSIDES
101Neutrophil count decreasedOFFSIDES
102Normal deliveryOFFSIDES
103ObstructionOFFSIDES
104OliguriaOFFSIDES
105Oropharyngeal painOFFSIDES
106Oropharyngeal plaqueOFFSIDES
107PemphigusOFFSIDES
108PeritonsillitisOFFSIDES
109PertussisOFFSIDES
110Pneumatosis Cystoides IntestinalisOFFSIDES
111PneumothoraxOFFSIDES
112PoriomaniaOFFSIDES
113Protein total decreasedOFFSIDES
114Protein total increasedOFFSIDES
115Psychiatric symptomOFFSIDES
116PyelonephritisOFFSIDES
117Pyoderma GangrenosumOFFSIDES
118Renal tubular disorderOFFSIDES
119Respiratory FailureOFFSIDES
120RhabdomyolysisOFFSIDES
121SchizophreniaOFFSIDES
122ScotomaOFFSIDES
123Self MutilationOFFSIDES
124Sick Sinus SyndromeOFFSIDES
125Skin ErosionOFFSIDES
126Skin necrosisOFFSIDES
127Stevens-Johnson SyndromeOFFSIDES
128SubileusOFFSIDES
129Sudden Cardiac DeathOFFSIDES
130TonsillitisOFFSIDES
131Tooth ResorptionOFFSIDES
132Unresponsive to stimuliOFFSIDES
133Urine ketone body presentOFFSIDES
134Urine osmolarity increasedOFFSIDES
135Urobilin urine presentOFFSIDES
136Uterine CancerOFFSIDES
137VitrectomyOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120239

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.