MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

naringin

(DFPMSGMNTNDNHN-ZPHOTFPESA-N)

Structure

SMILES: OC[C@H]1O[C@@H](Oc2cc(O)c3c(c2)O[C@@H](CC3=O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O
Molecular Formula:: C27H32O14
Molecular Weight:: 580.535
Log P:: -1.1652
Hydrogen Bond Acceptor:: 14
Hydrogen Bond Donor:: 8
TPSA:: 225.06
CAS Number(s):: 10236-47-2

Synonym(s)

naringin

4',5,7-trihydroxyflavanone 7-rhamnoglucoside

Cyclorel

aurantiin

naringenin-7-hesperidoside

naringin dihydrochalcone

naringin sodium

External Link(s)

MeSH	C005274
PubChem Compound	442428
BindingDB	50241582
ChEBI	28819
CHEMBL	CHEMBL451532
IUPHAR/BPS Guide to PHARMACOLOGY	4738
KEGG	cpd:C09789
ZINC	8143604

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Acute Lung Injury	23603004	CTD
2	Acute kidney injury	21600195	CTD
3	Bone Resorption	21820093 21835177	CTD
4	Cardiomegaly	27174133	CTD
5	Cardiotoxicity	27174133	CTD
6	Chemical and Drug Induced Liver Injury	20950607	CTD
7	Dermatitis, Allergic Contact	16945185	CTD
8	Dyslipidemias	22198281	CTD
9	Edema	27174133	CTD
10	Encephalomalacia	26120027	CTD
11	Fatty Liver	22198281	CTD
12	Femur Head Necrosis	30878453	CTD
13	Fibrosis	27174133	CTD
14	Gliosis	26120027	CTD
15	Inflammation	23603004 24376342 27174133	CTD
16	Insulin Resistance	22198281	CTD
17	Kidney Diseases	26612654	CTD
18	Myocardial Infarction	17084010 17188415 17289242	CTD
19	Necrosis	18793633	CTD
20	Neoplasm Invasiveness	24975661 25866363 26721195	CTD
21	Nerve Degeneration	30130594	CTD
22	Neurotoxicity Syndromes	26120027	CTD
23	Osteoporosis	18495116 21835177 25181344	CTD
24	Paraquat lung	23603004	CTD
25	Plaque, Atherosclerotic	21684135	CTD
26	Pleurisy	25117567	CTD
27	Pneumonia	22575871	CTD
28	Pulmonary Fibrosis	23603004	CTD
29	Respiratory Hypersensitivity	22575871	CTD
30	Ventricular Dysfunction, Left	27174133	CTD
31	anaphylaxis	24131540	CTD

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