cerivastatin
(GPUADMRJQVPIAS-QCVDVZFFSA-M)
Structure
- SMILES
- COCc1c(c2ccc(cc2)F)c(/C=C/[C@H](C[C@H](CC(=O)[O-])O)O)c(nc1C(C)C)C(C)C.[Na+]
- Molecular Formula:
- C26H33FNNaO5
- Molecular Weight:
- 481.532
- Log P:
- 3.5460
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 2
- TPSA:
- 102.71
- CAS Number(s):
- 143201-11-0
Synonym(s)
1.
cerivastatin
2.
6-Heptenoic acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-, monosodium salt, (S-(R*,S*-(E)))-
3.
7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyrid-3-yl)-3,5-dihydroxy-6-heptenoate sodium salt
4.
Bay w 6228
5.
Baycol
6.
Certa
7.
Kazak
8.
Lipobay
9.
cerivastatin sodium
10.
rivastatin
External Link(s)
| MeSH | C086276 |
| PubChem Compound | 23663992 |
| ChEBI | 3559 |
| CHEMBL | CHEMBL1200563 |
| KEGG | dr:D00889 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Arthralgia | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 2 | Fatigue | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 3 | Myalgia | FAERS: 2 Canada Vigilance: 15 | Canada Vigilance US FAERS | |
| 4 | Renal pain | FAERS: 2 | US FAERS | |
| 5 | Ankle Fracture | FAERS: 1 | US FAERS | |
| 6 | Asthenia | FAERS: 1 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 7 | Asthma | FAERS: 1 | US FAERS | |
| 8 | Back Pain | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 9 | Chromaturia | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 10 | Dehydration | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 11 | Duodenitis | FAERS: 1 | US FAERS | |
| 12 | Dyspepsia | FAERS: 1 | US FAERS | |
| 13 | Leukoencephalopathy | FAERS: 1 | US FAERS | |
| 14 | Mental status changes | FAERS: 1 | US FAERS | |
| 15 | Nasal Polyps | FAERS: 1 | US FAERS | |
| 16 | Nasopharyngitis | FAERS: 1 | US FAERS | |
| 17 | Nausea | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 18 | Pain | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 19 | Renal tubular necrosis | FAERS: 1 | US FAERS | |
| 20 | Retinal Artery Occlusion | FAERS: 1 | US FAERS | |
| 21 | Rhabdomyolysis | FAERS: 1 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 22 | Vertigo | FAERS: 1 | US FAERS | |
| 23 | Vestibular Neuronitis | FAERS: 1 | US FAERS | |
| 24 | Vomiting | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 25 | jaundice | FAERS: 1 | US FAERS | |
| 26 | muscle injury | FAERS: 1 | US FAERS | |
| 27 | Abdominal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Abdominal discomfort | Canada Vigilance: 2 | Canada Vigilance | |
| 29 | Alopecia | Canada Vigilance: 1 | Canada Vigilance | |
| 30 | Angina Pectoris | Canada Vigilance: 2 | Canada Vigilance | |
| 31 | Aphonia | Canada Vigilance: 1 | Canada Vigilance | |
| 32 | Arthritis | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Biliary cirrhosis | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Blood cholesterol increased | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Blood creatine phosphokinase increased | Canada Vigilance: 7 | Canada Vigilance | |
| 36 | Burning sensation | Canada Vigilance: 1 | Canada Vigilance | |
| 37 | Cerebrovascular accident | Canada Vigilance: 1 | Canada Vigilance | |
| 38 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 39 | Dizziness | Canada Vigilance: 1 | Canada Vigilance | |
| 40 | Electrolyte imbalance | Canada Vigilance: 1 | Canada Vigilance | |
| 41 | Eye pain | Canada Vigilance: 1 | Canada Vigilance | |
| 42 | Headache | Canada Vigilance: 1 | Canada Vigilance | |
| 43 | Hepatomegaly | Canada Vigilance: 1 | Canada Vigilance | |
| 44 | Intervertebral disc disorder | Canada Vigilance: 1 | Canada Vigilance | |
| 45 | Laryngospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 46 | Medication Error | Canada Vigilance: 1 | Canada Vigilance | |
| 47 | Mental impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 48 | Musculoskeletal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Musculoskeletal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 50 | Musculoskeletal stiffness | Canada Vigilance: 1 | Canada Vigilance | |
| 51 | Myoglobinuria | Canada Vigilance: 1 | Canada Vigilance | |
| 52 | Neck Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 53 | Nephrolithiasis | Canada Vigilance: 1 | Canada Vigilance | |
| 54 | Peripheral embolism | Canada Vigilance: 1 | Canada Vigilance | |
| 55 | Personality Change | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Pharyngeal swelling | Canada Vigilance: 2 | Canada Vigilance | |
| 57 | Polymyalgia Rheumatica | Canada Vigilance: 1 | Canada Vigilance | |
| 58 | Proteinuria | Canada Vigilance: 1 | Canada Vigilance | |
| 59 | Synovitis | Canada Vigilance: 1 | Canada Vigilance | |
| 60 | Tremor | Canada Vigilance: 1 | Canada Vigilance | |
| 61 | Urinary tract infection | Canada Vigilance: 1 | Canada Vigilance | |
| 62 | Urticaria | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 64 | Weight decreased | Canada Vigilance: 2 | Canada Vigilance |
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