Vincristine
(AQTQHPDCURKLKT-PNYVAJAMSA-N)
Structure
- SMILES
- OS(=O)(=O)O.O=CN1c2cc(OC)c(cc2[C@]23[C@@H]1[C@@](O)(C(=O)OC)[C@H](OC(=O)C)[C@]1([C@@H]3N(CC2)CC=C1)CC)[C@]1(C[C@H]2CN(CCc3c1[nH]c1c3cccc1)C[C@](C2)(O)CC)C(=O)OC
- Molecular Formula:
- C46H58N4O14S
- Molecular Weight:
- 923.036
- Log P:
- 4.5222
- Hydrogen Bond Acceptor:
- 17
- Hydrogen Bond Donor:
- 5
- TPSA:
- 254.15
- CAS Number(s):
- 2068-78-2
Synonym(s)
1.
Vincristine
2.
Leurocristine
3.
Citomid
4.
Farmistin
5.
Oncovin
6.
Oncovine
7.
Onkocristin
8.
Vincasar
9.
Vincasar PFS
10.
Vincristin Bristol
11.
Vincristin medac
12.
Vincristine Sulfate
13.
Vincrisul
14.
Vintec
15.
cellcristin
16.
PFS, Vincasar
17.
Sulfate, Vincristine
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Alanine Aminotransferase Increased | FAERS: 2 | US FAERS | |
| 2 | Aspartate Aminotransferase Increased | FAERS: 2 | US FAERS | |
| 3 | Acute myocardial infarction | FAERS: 1 | US FAERS | |
| 4 | Asthenia | FAERS: 1 | US FAERS | |
| 5 | Cellulitis | FAERS: 1 | US FAERS | |
| 6 | Disease Progression | FAERS: 1 | US FAERS | |
| 7 | Disease recurrence | FAERS: 1 | US FAERS | |
| 8 | Drug administration error | FAERS: 1 | US FAERS | |
| 9 | Enterococcal infection | FAERS: 1 | US FAERS | |
| 10 | Febrile Neutropenia | FAERS: 1 | US FAERS | |
| 11 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 12 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 13 | Infection | FAERS: 1 | US FAERS | |
| 14 | Injection site erythema | FAERS: 1 | US FAERS | |
| 15 | Injection site extravasation | FAERS: 1 | US FAERS | |
| 16 | Injection site vesicles | FAERS: 1 | US FAERS | |
| 17 | Lung Abscess | FAERS: 1 | US FAERS | |
| 18 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 19 | Malignant neoplasm progression | FAERS: 1 | US FAERS | |
| 20 | Malnutrition | FAERS: 1 | US FAERS | |
| 21 | Metapneumovirus infection | FAERS: 1 | US FAERS | |
| 22 | Moaning | FAERS: 1 | US FAERS | |
| 23 | Monoplegia | FAERS: 1 | US FAERS | |
| 24 | Pain | FAERS: 1 | US FAERS | |
| 25 | Pancytopenia | FAERS: 1 | US FAERS | |
| 26 | Pneumonia | FAERS: 1 | US FAERS | |
| 27 | Rhinovirus infection | FAERS: 1 | US FAERS | |
| 28 | Sepsis | FAERS: 1 | US FAERS | |
| 29 | Toxic Shock Syndrome | FAERS: 1 | US FAERS | |
| 30 | Weight decreased | FAERS: 1 | US FAERS | |
| 31 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 32 | Disorientation | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Hemiplegia | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Hypotension | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Injection site pain | Canada Vigilance: 1 | Canada Vigilance |
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