Glutethimide
(JMBQKKAJIKAWKF-UHFFFAOYSA-N)
Structure
- SMILES
- CCC1(CCC(=O)NC1=O)c1ccccc1
- Type(s)
- Approved; Illicit
- ATC code(s)
- N05CE01
- Molecular Formula:
- C13H15NO2
- Molecular Weight:
- 217.264
- Log P:
- 2.0998
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 1
- TPSA:
- 46.17
- CAS Number(s):
- 77-21-4
Synonym(s)
1.
Glutethimide
2.
Doriden
3.
Noxiron
External Link(s)
| MeSH | D005984 |
| PubChem Compound | 3487 |
| ChEBI | 5439 |
| CHEMBL | CHEMBL1102 |
| DrugBank | DB01437 |
| DrugCentral | 1313 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 7192 |
| KEGG | cpd:C07489 dr:D00532 |
| Therapeutic Target Database | D0Z9NZ |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Accidental overdose | Canada Vigilance: 3 | Canada Vigilance | |
| 2 | Agitation | Canada Vigilance: 1 | Canada Vigilance | |
| 3 | Ataxia | Canada Vigilance: 1 | Canada Vigilance | |
| 4 | Cerebellar Ataxia | 5709841 | CTD | |
| 5 | Completed Suicide | Canada Vigilance: 10 | Canada Vigilance | |
| 6 | Dehydration | Canada Vigilance: 1 | Canada Vigilance | |
| 7 | Dizziness | Canada Vigilance: 1 | Canada Vigilance | |
| 8 | Drug Dependence | Canada Vigilance: 1 | Canada Vigilance | |
| 9 | Dysphemia | Canada Vigilance: 1 | Canada Vigilance | |
| 10 | Erythema | Canada Vigilance: 2 | Canada Vigilance | |
| 11 | Hallucinations | 5709841 | CTD | |
| 12 | Headache | Canada Vigilance: 1 | Canada Vigilance | |
| 13 | Hypersensitivity | Canada Vigilance: 2 | Canada Vigilance | |
| 14 | Hypocalcemia | 1273917 | CTD | |
| 15 | Nausea | Canada Vigilance: 1 | Canada Vigilance | |
| 16 | Neuritis | 5709841 | CTD | |
| 17 | Overdose | Canada Vigilance: 1 | Canada Vigilance | |
| 18 | Pruritus | Canada Vigilance: 9 | Canada Vigilance | |
| 19 | Purpura | Canada Vigilance: 3 | Canada Vigilance | |
| 20 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 21 | Seizures | 565846 1273917 | CTD | |
| 22 | Skin reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 23 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 24 | Substance Withdrawal Syndrome | 3348460 6822484 | CTD | |
| 25 | Suicide attempt | Canada Vigilance: 2 | Canada Vigilance | |
| 26 | Tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 27 | Therapeutic response unexpected | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Tremor | Canada Vigilance: 1 | Canada Vigilance | |
| 29 | Urticaria | Canada Vigilance: 7 | Canada Vigilance | |
| 30 | Vomiting | Canada Vigilance: 2 | Canada Vigilance |
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