MetaADEDB 2.0 @ LMMD
Foscarnet
(ZJAOAACCNHFJAH-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)P(=O)(O)O
Type(s)
Approved
ATC code(s)
J05AD01
Molecular Formula:
CH3O5P
Molecular Weight:
126.005
Log P:
-0.1579
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
3
TPSA:
104.64
CAS Number(s):
4428-95-9
Synonym(s)
1.
Foscarnet
2.
Phosphonoformate
3.
Phosphonoformic Acid
4.
Foscarnet Barium (2:3) Salt
5.
Foscarnet Calcium (2:3) Salt
6.
Foscarnet Disodium Salt
7.
Foscarnet Magnesium (2:3) Salt
8.
Foscarnet Manganese (2+) (2:3) Salt
9.
Foscarnet Sodium
10.
Foscarnet Sodium Hexahydrate
11.
Foscarnet Trilithium Salt
12.
Foscarnet Tripotassium Salt
13.
Foscarnet Trisodium Salt
14.
Foscavir
15.
Trisodium Phosphonoformate
External Link(s)
MeSHD017245
PubChem Compound3415
BindingDB50011181
ChEBI127780
CHEMBLCHEMBL666
DrugBankDB00529
DrugCentral1241
IUPHAR/BPS Guide to PHARMACOLOGY5497
KEGGcpd:C06456
ZINC8101109
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AtaxiaFAERS: 1OFFSIDES
SIDER
US FAERS
2Chest discomfortFAERS: 1US FAERS
3Cytomegalovirus test positiveFAERS: 1OFFSIDES
US FAERS
4DizzinessFAERS: 1OFFSIDES
SIDER
US FAERS
5Drug administration errorFAERS: 1US FAERS
6HeadacheFAERS: 1SIDER
US FAERS
7Immune reconstitution syndromeFAERS: 1US FAERS
8Incorrect drug dosage form administeredFAERS: 1US FAERS
9NauseaFAERS: 19113493CTD
OFFSIDES
SIDER
US FAERS
10Pleuritic painFAERS: 1US FAERS
11Renal salt-wasting syndromeFAERS: 1OFFSIDES
US FAERS
12RetinitisFAERS: 11335467
8384030
CTD
US FAERS
13Septic ShockFAERS: 1OFFSIDES
US FAERS
14AIDS-Related Opportunistic Infections7802522
11363124
CTD
15Abdominal PainSIDER
16Abnormal plateletsSIDER
17Abnormal visionOFFSIDES
18AbscessSIDER
19AcidosisOFFSIDES
SIDER
20Acute graft versus host disease in liverOFFSIDES
21Acute kidney injury

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CTD
22Acute respiratory failureOFFSIDES
23Adrenocortical insufficiency chronicOFFSIDES
24AgeusiaOFFSIDES
25Aggressive reactionSIDER
26AgitationSIDER
27AgranulocytosisSIDER
28Alanine Aminotransferase IncreasedOFFSIDES
SIDER
29Albumin globulin ratio abnormalSIDER
30AlbuminuriaSIDER
31Altered state of consciousnessOFFSIDES
32AmnesiaOFFSIDES
SIDER
33AnorexiaOFFSIDES
SIDER
34AnosmiaOFFSIDES
35AnuriaOFFSIDES
36Anxiety Disorders8384030CTD
37AnxietySIDER
38ApathyOFFSIDES
39AphasiaSIDER
40ArthralgiaSIDER
41Aspartate Aminotransferase IncreasedSIDER
42AspergillosisOFFSIDES
43AstheniaSIDER
44BK virus infectionOFFSIDES
45Back PainSIDER
46Bacterial EndocarditisOFFSIDES
47Band neutrophil percentage increasedOFFSIDES
48Blood GlucoseOFFSIDES
49Blood albumin decreasedOFFSIDES
50Blood alkaline phosphatase decreasedOFFSIDES
51Blood alkaline phosphatase increasedOFFSIDES
SIDER
52Blood amylase increasedOFFSIDES
53Blood chloride decreasedOFFSIDES
54Blood cholesterolOFFSIDES
55Blood creatinine decreasedSIDER
56Blood creatinine increasedOFFSIDES
SIDER
57Blood electrolytes abnormalOFFSIDES
58Blood lactate dehydrogenase increasedOFFSIDES
SIDER
59Blood phosphorus increasedOFFSIDES
60Blood potassium decreasedOFFSIDES
61Blood sodiumOFFSIDES
62Blood triglycerides increasedOFFSIDES
63Blood urea increasedOFFSIDES
SIDER
64Blood uric acidOFFSIDES
65Bronchoalveolar LavageOFFSIDES
66BronchospasmSIDER
67CYTOMEGALOVIRUS ANTIGENOFFSIDES
68CachexiaSIDER
69Calcinosis24561004CTD
70Candida sepsisOFFSIDES
71Cardiac ArrestSIDER
72Catheter related infectionOFFSIDES
73Chest PainSIDER
74ChillsSIDER
75Clostridium difficile colitisOFFSIDES
76Colitis11362300CTD
77Color blindnessOFFSIDES
78Complications of bone marrow transplantOFFSIDES
79Concomitant disease aggravatedOFFSIDES
80ConjunctivitisSIDER
81ConstipationSIDER
82Cramps of lower extremitiesSIDER
83Creatinine lowSIDER
84Creatinine renal clearance decreasedOFFSIDES
85Culture positiveOFFSIDES
86CystOFFSIDES
87Cytomegalovirus Infections

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CTD
88Cytomegalovirus Retinitis

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CTD
89Cytomegalovirus chorioretinitisOFFSIDES
90Cytomegalovirus duodenitisOFFSIDES
91Cytomegalovirus enterocolitisOFFSIDES
92DehydrationSIDER
93DementiaSIDER
94Depressed Level of ConsciousnessSIDER
95DermatitisSIDER
96Diabetes InsipidusSIDER
97DiscomfortSIDER
98Disseminated Intravascular CoagulationOFFSIDES
99Drug ineffectiveOFFSIDES
100Drug resistanceOFFSIDES
101DyspepsiaSIDER
102Dystonia18356641CTD
103DysuriaOFFSIDES
SIDER
104Electroencephalogram abnormalSIDER
105Electrolyte imbalanceSIDER
106EncephalitisOFFSIDES
107Enterococcal sepsisOFFSIDES
108EnterocolitisOFFSIDES
109EpilepsyOFFSIDES
110Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
111Erythema MultiformeSIDER
112Eye painSIDER
113FatigueSIDER
114Febrile bone marrow aplasiaOFFSIDES
115Feeling abnormalSIDER
116Fever2560634CTD
117FibromyalgiaOFFSIDES
118Flank PainOFFSIDES
119FlatulenceSIDER
120FlushingSIDER
121FormicationOFFSIDES
122Fungal DNA test positiveOFFSIDES
123Gamma-Glutamyltransferase IncreasedOFFSIDES
SIDER
124Gastric ulcerOFFSIDES
125Gastrointestinal PainSIDER
126GlaucomaOFFSIDES
127GlobulinuriaOFFSIDES
128Glomerulonephritis7618652
10360595
CTD
129HIV Infections7949502
11050094
11362904
CTD
130HIV Wasting SyndromeOFFSIDES
131Heart failure8386905CTD
132Hematuria10231404
10360595
CTD
133Hepatitis, Viral, Human9059069CTD
134HepatitisOFFSIDES
135Herpesviridae Infections7949502
9761526
CTD
136Histiocytosis haematophagicOFFSIDES
137Human Herpesvirus 6 encephalitis18277595CTD
138Human polyomavirus infectionOFFSIDES
139HydronephrosisOFFSIDES
140Hypercalcemia9223751
9792397
CTD
141Hypocalcemia8384030CTD
142Hypokalemia1335467
8384030
CTD
143Hyponatremia18277595CTD
144Hypophosphatemia8384030CTD
145HypotensionSIDER
146ImmunosuppressionOFFSIDES
147Impaired insulin secretionOFFSIDES
148InfectionSIDER
149Influenza-like symptomsSIDER
150Injection site inflammationSIDER
151Injection site painSIDER
152Intraocular inflammationOFFSIDES
153Inulin renal clearance decreasedOFFSIDES
154Kidney Diseases

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CTD
155Kidney Failure, Chronic9740173CTD
156Kidney FailureOFFSIDES
157Lactic dehydrogenase activity increasedSIDER
158LeukoencephalopathyOFFSIDES
159Leukopenia neonatalOFFSIDES
160LeukopeniaSIDER
161LymphadenopathySIDER
162Lymphocyte count decreasedOFFSIDES
163Lymphocyte percentage decreasedOFFSIDES
164Magnesium Deficiency8384030CTD
165MalaiseSIDER
166Malignant neoplasm progressionOFFSIDES
167MeningitisSIDER
168Metabolic acidosisOFFSIDES
169Monocyte percentage decreasedOFFSIDES
170Multiple MyelomaOFFSIDES
171Muscle Cramp7803878CTD
172Musculoskeletal discomfortSIDER
173Musculoskeletal stiffnessOFFSIDES
174MyalgiaSIDER
175MyopathySIDER
176MyositisSIDER
177Nephritis, Interstitial2560634CTD
178NephrolithiasisSIDER
179Nephrotic Syndrome10231404
10360595
CTD
180NervousnessSIDER
181Neuritis9761526CTD
182Neuroblastoma recurrentOFFSIDES
183NeuropathySIDER
184Neutropenia7802522CTD
SIDER
185Neutrophil morphology abnormalOFFSIDES
186NocturiaSIDER
187NystagmusOFFSIDES
188ObstructionOFFSIDES
189PainSIDER
190PalpitationsSIDER
191PancreatitisSIDER
192PancytopeniaSIDER
193Paresthesia7803878CTD
194Pathogen resistanceOFFSIDES
195Penile Diseases9113493CTD
196Pericardial effusionOFFSIDES
197PharyngitisSIDER
198Pneumocystis jiroveci pneumoniaOFFSIDES
199PneumothoraxOFFSIDES
SIDER
200Polyuria8604715
8836823
CTD
SIDER
201Protein total increasedOFFSIDES
202PruritusSIDER
203PseudolymphomaSIDER
204Pulmonary HypertensionOFFSIDES
205Rash erythematousSIDER
206Renal Insufficiency2560634
9740154
CTD
207Renal tubular disorderOFFSIDES
208Respiratory FailureOFFSIDES
SIDER
209Respiratory InsufficiencySIDER
210Respiratory syncytial virus test positiveOFFSIDES
211Retinal Necrosis Syndrome, Acute17406046CTD
212RhabdomyolysisSIDER
213RhinitisSIDER
214Seizures

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CTD
215SepsisSIDER
216Serum SicknessOFFSIDES
217Sinus TachycardiaSIDER
218SinusitisSIDER
219Skin UlcerSIDER
220SomnolenceSIDER
221Spasm8384030CTD
222Status EpilepticusOFFSIDES
223Stenotrophomonas infectionOFFSIDES
224Stevens-Johnson Syndrome25811541CTD
SIDER
225StridorSIDER
226StuporSIDER
227TensionSIDER
228Tetany7578826CTD
229ThirstSIDER
230ThrombocytopeniaSIDER
231ThrombosisSIDER
232Toxic Epidermal NecrolysisSIDER
233Transfusion-Related Acute Lung InjuryOFFSIDES
234TremorSIDER
235Trichosporon infectionOFFSIDES
236Ulcerative stomatitisSIDER
237Urinary RetentionSIDER
238Urinary tract infectionSIDER
239Urine output increasedSIDER
240Uveitis9761526CTD
241VasospasmOFFSIDES
242Ventricular arrhythmiaSIDER
243Vesiculobullous rashSIDER
244Viral mutation identifiedOFFSIDES
245Viral myocarditisOFFSIDES
246Virus urine test positiveOFFSIDES
247VomitingSIDER
248Water-Electrolyte Imbalance7802522
8384030
CTD
249Weight decreasedSIDER
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