amlodipine, atorvastatin drug combination
(KIOJIUJTZWEWGA-DJNTWTPDSA-L)
Structure
- SMILES
- OS(=O)(=O)c1ccccc1.O[C@@H](C[C@H](CC(=O)[O-])O)CCn1c(C(C)C)c(c(c1c1ccc(cc1)F)c1ccccc1)C(=O)Nc1ccccc1.O[C@@H](C[C@H](CC(=O)[O-])O)CCn1c(C(C)C)c(c(c1c1ccc(cc1)F)c1ccccc1)C(=O)Nc1ccccc1.NCCOCC1=C(C(=O)OCC)C(C(=C(N1)C)C(=O)OC)c1ccccc1Cl.[Ca+2]
- Molecular Formula:
- C92H99CaClF2N6O18S
- Molecular Weight:
- 1722.390
- Log P:
- 15.4133
- Hydrogen Bond Acceptor:
- 24
- Hydrogen Bond Donor:
- 9
- TPSA:
- 391.87
- CAS Number(s):
- 930274-47-8
Synonym(s)
1.
amlodipine, atorvastatin drug combination
2.
Caduet
3.
amlodipine - atorvastatin
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Headache | FAERS: 3 | 18174006 | CTD US FAERS |
| 3 | Dizziness | FAERS: 2 | US FAERS | |
| 4 | Hypersensitivity | FAERS: 2 | US FAERS | |
| 5 | Nausea | FAERS: 2 | US FAERS | |
| 6 | Product substitution issue | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 7 | Abdominal discomfort | FAERS: 1 | US FAERS | |
| 8 | Asthenia | FAERS: 1 | US FAERS | |
| 9 | Blood pressure inadequately controlled | FAERS: 1 | US FAERS | |
| 10 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 11 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 12 | Exposure via ingestion | FAERS: 1 | US FAERS | |
| 13 | Fatigue | FAERS: 1 | US FAERS | |
| 14 | Malaise | FAERS: 1 | US FAERS | |
| 15 | Myalgia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | Product packaging quantity issue | FAERS: 1 | US FAERS | |
| 17 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 18 | Sinusitis | FAERS: 1 | US FAERS | |
| 19 | Cardiomegaly | 18389332 | CTD | |
| 20 | Constipation | 18174006 | CTD | |
| 21 | Dyslipidemias | 18174006 | CTD | |
| 22 | Edema | 18174006 | CTD | |
| 23 | Pain | 18174006 | CTD |
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