MetaADEDB 2.0 @ LMMD
MK-0524
(NXFFJDQHYLNEJK-CYBMUJFWSA-N)
Structure
SMILES
OC(=O)C[C@H]1CCc2c1n(Cc1ccc(cc1)Cl)c1c2cc(cc1S(=O)(=O)C)F
Type(s)
Approved; Investigational; Withdrawn
Molecular Formula:
C21H19ClFNO4S
Molecular Weight:
435.896
Log P:
5.4709
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
1
TPSA:
84.75
CAS Number(s):
571170-77-9
Synonym(s)
1.
MK-0524
2.
(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta(b)indol-3-yl acetic acid
3.
laropiprant
External Link(s)
MeSHC518174
PubChem Compound9867642
BindingDB50205275
ChEBI135942
CHEMBLCHEMBL426559
DrugBankDB11629
DrugCentral4326
IUPHAR/BPS Guide to PHARMACOLOGY3356
KEGGdr:D08940
Therapeutic Target DatabaseD0WL5V
D0KX9I
ZINC3961849
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Dyslipidemias21291812CTD
2Flushing

View details

17392721
18308010
19166443
19243712
19246721
19454860
19576324
19602880
19833861
20107202
 		CTD
3Hypercholesterolemia21291812CTD
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