MetaADEDB 2.0 @ LMMD
Atazanavir Sulfate
(DQSGVVGOPRWTKI-QVFAWCHISA-N)
Structure
SMILES
OS(=O)(=O)O.COC(=O)N[C@@H](C(C)(C)C)C(=O)NN(Cc1ccc(cc1)c1ccccn1)C[C@@H]([C@H](Cc1ccccc1)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O
Molecular Formula:
C38H54N6O11S
Molecular Weight:
802.934
Log P:
6.2032
Hydrogen Bond Acceptor:
17
Hydrogen Bond Donor:
7
TPSA:
254.2
CAS Number(s):
229975-97-7
Synonym(s)
1.
Atazanavir Sulfate
2.
3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-2,5,6,10,13-pentaazatetradecanedioic acid dimethyl ester
3.
Atazanavir
4.
BMS 232632
5.
BMS-232632
6.
BMS-232632-05
7.
BMS232632
8.
CGP 73547
9.
CGP 75136
10.
CGP 75176
11.
CGP 75355
12.
CGP-73547
13.
CGP-75136
14.
CGP-75176
15.
CGP-75355
16.
CGP75136
17.
CGP75176
18.
CGP75355
19.
Reyataz
20.
232632, BMS
21.
BMS 232632 05
22.
BMS23263205
23.
CGP73547
External Link(s)
MeSHD000069446
PubChem Compound25058165
158550
ChEBI31243
CHEMBLCHEMBL1200678
KEGGdr:D01276
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1NephrolithiasisFAERS: 517502736
18090291
19246127		CTD
US FAERS
2PregnancyFAERS: 5US FAERS
3HyperkeratosisFAERS: 4US FAERS
4Acanthosis NigricansFAERS: 3US FAERS
5Congenital hydronephrosisFAERS: 2US FAERS
6HypersensitivityFAERS: 2US FAERS
7Keratosis pilarisFAERS: 2US FAERS
8Ocular icterusFAERS: 2US FAERS
9Pierre Robin SyndromeFAERS: 2US FAERS
10Pregnancy on contraceptiveFAERS: 2US FAERS
11Acute kidney injuryFAERS: 117615423CTD
US FAERS
12AlopeciaFAERS: 1US FAERS
13Blood creatinine increasedFAERS: 1US FAERS
14Cardiac function test abnormalFAERS: 1US FAERS
15Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
16Flank PainFAERS: 1US FAERS
17Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
18Lipodystrophy acquiredFAERS: 1US FAERS
19Live BirthFAERS: 1US FAERS
20Maternal exposure during pregnancyFAERS: 1US FAERS
21Myocardial InfarctionFAERS: 1US FAERS
22NephrectomyFAERS: 1US FAERS
23Pregnancy on oral contraceptiveFAERS: 1US FAERS
24Product use in unapproved indicationFAERS: 1US FAERS
25ProteinuriaFAERS: 1US FAERS
26PyelonephritisFAERS: 1US FAERS
27Suicide attemptFAERS: 1US FAERS
28Transaminases increasedFAERS: 1US FAERS
29Ureteral stent insertionFAERS: 1US FAERS
30UreterolithiasisFAERS: 1US FAERS
31jaundiceFAERS: 119637415CTD
US FAERS
32Chemical and Drug Induced Liver Injury19955297
24014644		CTD
33Choledocholithiasis19955297CTD
34Dyslipidemias27378623CTD
35HIV Infections16603854
17177581
23548184		CTD
36HIV Seropositivity20523203CTD
37Hydronephrosis17108352CTD
38Hyperbilirubinemia17053366
19955297		CTD
39Kidney Calculi17053366CTD
40Kidney Failure, Chronic20523203CTD
41Nephritis, Interstitial16779906CTD
42Renal Colic17053366CTD
43Rhabdomyolysis17615423CTD
44Stevens-Johnson Syndrome25811541CTD
45Torsades de Pointes19637415CTD
46Ureteral Calculi17108352CTD
47Urolithiasis17879904CTD
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