MetaADEDB 2.0 @ LMMD
fanasil, pyrimethamine drug combination
(LUBUTTBEBGYNJN-UHFFFAOYSA-N)
Structure
SMILES
COc1c(OC)ncnc1NS(=O)(=O)c1ccc(cc1)N.CCc1nc(N)nc(c1c1ccc(cc1)Cl)N
Molecular Formula:
C24H27ClN8O4S
Molecular Weight:
559.040
Log P:
6.2980
Hydrogen Bond Acceptor:
12
Hydrogen Bond Donor:
4
TPSA:
202.63
CAS Number(s):
37338-39-9
Synonym(s)
1.
fanasil, pyrimethamine drug combination
2.
Fansidar
3.
Suldox
4.
fanasil - pyrimethamine
5.
sulfadoxine-pyrimethamine
6.
sulphadoxine-pyrimethamine
External Link(s)
MeSHC001205
PubChem Compound65404
CHEMBLCHEMBL3137690
KEGGdr:D02448
Therapeutic Target DatabaseD04UZN
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1PancytopeniaFAERS: 3US FAERS
2DizzinessFAERS: 2US FAERS
3Drug exposure during pregnancyFAERS: 2US FAERS
4DeliriumFAERS: 1US FAERS
5Drug resistanceFAERS: 1US FAERS
6FatigueFAERS: 1US FAERS
7HeadacheFAERS: 1US FAERS
8OverdoseFAERS: 1US FAERS
9Stevens-Johnson SyndromeFAERS: 12147046CTD
US FAERS
10Urinary IncontinenceFAERS: 1US FAERS
11VomitingFAERS: 1US FAERS
12Anemia18008242
20595482		CTD
13Anorexia18547415CTD
14Blindness2147046CTD
15Chemical and Drug Induced Liver Injury2949680CTD
16ConjunctivitisCanada Vigilance: 1Canada Vigilance
17DyspepsiaCanada Vigilance: 1Canada Vigilance
18Fever18547415CTD
19Hypotension, Orthostatic3125918CTD
20Kidney Diseases3155635CTD
21Liver Failure2949680CTD
22Liver diseases3155635CTD
23Malaria, Falciparum3125918
18154655		CTD
24Malaria

View details

3371193
6335683
7325735
15934850
16012293
17617910
18008240
18008241
18008242
20194698
 		CTD
25Muscle Weakness18547415CTD
26Parasitemia17617910CTD
27Pericarditis3155635CTD
28Pregnancy Complications, Parasitic17617910CTD
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120269

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.