MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Methoxyflurane

(RFKMCNOHBTXSMU-UHFFFAOYSA-N)

Structure

SMILES: COC(C(Cl)Cl)(F)F
Type(s): Approved; Investigational; Vet_approved
ATC code(s): N02BG09
Molecular Formula:: C3H4Cl2F2O
Molecular Weight:: 164.966
Log P:: 2.0293
Hydrogen Bond Acceptor:: 1
Hydrogen Bond Donor:: 0
TPSA:: 9.23
CAS Number(s):: 76-38-0

Synonym(s)

Methoxyflurane

Methofluranum

Anecotan

Penthrane

Pentrane

External Link(s)

MeSH	D008733
PubChem Compound	4116
ChEBI	6843
CHEMBL	CHEMBL1341
DrugBank	DB01028
DrugCentral	1754
IUPHAR/BPS Guide to PHARMACOLOGY	7234
KEGG	cpd:C07517 dr:D00544
Therapeutic Target Database	D07SOO
ZINC	896988

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Acute kidney injury	Canada Vigilance: 3	View details 1036673 1111483 4414316 4649400 4722675 4739327 4767174 4829511 4852146 4853325 5007641 5061073 5083024 5107940 5134563 5286606 5454752 5469063 5725736	CTD Canada Vigilance
2	Anuria		4829511	CTD
3	Azotemia		View details 4767174 4818422 5454752 5469063 5725736	CTD
4	Brain Diseases		5798834	CTD
5	Chemical and Drug Induced Liver Injury		View details 585515 918705 4061098 4649400 4816183 5140659 5286606 5455938 5725736 6985498 7218059	CTD
6	Cystitis		5033780	CTD
7	Dehydration	Canada Vigilance: 4		Canada Vigilance
8	Drug ineffective	Canada Vigilance: 8		Canada Vigilance
9	Electrolyte imbalance	Canada Vigilance: 1		Canada Vigilance
10	Eosinophilia		4816183	CTD
11	Euphoric mood	Canada Vigilance: 1		Canada Vigilance
12	Fatty Liver		4061098	CTD
13	Fever		4816183	CTD
14	Fibrosis		4739327 4818422	CTD
15	Heart failure		626424	CTD
16	Hematuria		5033780	CTD
17	Hepatic Encephalopathy		5286606 5455938	CTD
18	Hepatic necrosis	Canada Vigilance: 1		Canada Vigilance
19	Hepatitis		5551804 6133801	CTD
20	Hypernatremia		View details 4722675 4818422 4853325 5007641 5033780 5725736	CTD
21	Hyperoxaluria		View details 180940 1259128 5454752 6499021	CTD
22	Inadequate analgesia	Canada Vigilance: 3		Canada Vigilance
23	Kidney Calculi		4856932	CTD
24	Kidney Diseases		View details 721016 982456 1239223 4061098 4416261 4816183 5107910 5109740 7059030 7218059 17006072	CTD
25	Kidney Failure, Chronic		4739327 4859609 5061073	CTD
26	Labor Pain		4541086	CTD
27	Myasthenia Gravis		5103772	CTD
28	Nausea	Canada Vigilance: 2		Canada Vigilance
29	Necrosis		View details 4853325 5140659 5286606 5725736	CTD
30	Nephrocalcinosis		View details 1111483 4722675 4739327 4818422 4829511 4853325 4859609 5033780 5061073 5469063	CTD
31	Nephrolithiasis	Canada Vigilance: 2		Canada Vigilance
32	Occupational Diseases		5103772	CTD
33	Oliguria		View details 4739327 4829511 4853325 5033780 5061073	CTD
34	Polyuria	Canada Vigilance: 3	View details 1239223 4414316 4688183 4705480 4705491 4739327 4767174 4818422 4829511 4853325 5007641 5033780 5045566 5083024 5109740 5134563 5469063 5725736	CTD Canada Vigilance
35	Postoperative Complications		4722675 4767174 6985498	CTD
36	Renal Insufficiency		View details 585515 725934 1253070 4688183 4705480 4705486 4705491 4818422 4834480 4856134 5033780 5095537 5695293 6499021	CTD
37	Renal tubular necrosis	Canada Vigilance: 1		Canada Vigilance
38	Respiratory Insufficiency		626424	CTD
39	Retinal Diseases		1111483 4852146	CTD
40	Substance-Related Disorders		918705	CTD
41	Tachycardia, Ventricular		5922	CTD
42	Tachycardia		4541086	CTD
43	Thrombophlebitis		4876884	CTD
44	Urination Disorders		982456 4705486	CTD
45	Vomiting	Canada Vigilance: 2	5024149	CTD Canada Vigilance
46	jaundice	Canada Vigilance: 2	5107940	CTD Canada Vigilance

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