MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Alfentanil

(IDBPHNDTYPBSNI-UHFFFAOYSA-N)

Structure

SMILES: COCC1(CCN(CC1)CCn1nnn(c1=O)CC)N(c1ccccc1)C(=O)CC
Type(s): Approved; Illicit
ATC code(s): N01AH02
Molecular Formula:: C21H32N6O3
Molecular Weight:: 416.517
Log P:: 1.3218
Hydrogen Bond Acceptor:: 9
Hydrogen Bond Donor:: 0
TPSA:: 85.49
CAS Number(s):: 71195-58-9

Synonym(s)

Alfentanil

Alfentanyl

Alfenta

Alfentanil Hydrochloride

Fanaxal

Limifen

R-39209

Rapifen

R 39209

10.

R39209

External Link(s)

MeSH	D015760
PubChem Compound	51263
BindingDB	83450 50008979
ChEBI	2569
CHEMBL	CHEMBL634
DrugBank	DB00802
DrugCentral	114
IUPHAR/BPS Guide to PHARMACOLOGY	7108
KEGG	cpd:C08005 dr:D07122
Therapeutic Target Database	D0G5QB
ZINC	601281

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cardiac Arrest	FAERS: 1		SIDER US FAERS
2	Drug ineffective	FAERS: 1		US FAERS
3	Nausea	FAERS: 1	11785593 15868998	CTD SIDER US FAERS
4	Procedural complication	FAERS: 1		OFFSIDES SIDER US FAERS
5	Product quality issue	FAERS: 1		US FAERS
6	Respiratory distress	FAERS: 1		US FAERS
7	Accidental overdose			OFFSIDES
8	Acidosis, Respiratory		1971163	CTD
9	Acute Coronary Syndrome			OFFSIDES
10	Adenocarcinoma			OFFSIDES
11	Agitation postoperative			SIDER
12	Agitation			SIDER
13	Agraphia			OFFSIDES
14	Alanine Aminotransferase Increased			OFFSIDES
15	Alopecia universalis			OFFSIDES
16	Anaphylactic shock			SIDER
17	Anaphylactoid Reaction			SIDER
18	Anaphylactoid syndrome of pregnancy			OFFSIDES
19	Angioedema			OFFSIDES
20	Anticholinergic Syndrome			OFFSIDES
21	Apallic syndrome			OFFSIDES
22	Apnea		View details 2311153 3930048 6122384 15167427 18005040	CTD
23	Arterial thrombosis			OFFSIDES
24	Ascites infection			OFFSIDES
25	Asthenia			SIDER
26	Atrial tachycardia			OFFSIDES
27	Blood albumin decreased			OFFSIDES
28	Blood phosphorus increased			OFFSIDES
29	Blood potassium decreased			OFFSIDES
30	Blood triglycerides increased			OFFSIDES
31	Bradycardia		View details 1361866 1514343 1971163 3137840 3149155 3919609 9037435	CTD OFFSIDES SIDER
32	Brain Death			OFFSIDES
33	Bronchospasm			SIDER
34	Carbon dioxide increased			SIDER
35	Catatonia		3022882	CTD OFFSIDES
36	Chest Pain		11785593	CTD
37	Chills			SIDER
38	Coagulation factor V level decreased			OFFSIDES
39	Colitis			OFFSIDES
40	Cyanosis			OFFSIDES
41	Cytolytic hepatitis			OFFSIDES
42	Deafness			OFFSIDES
43	Dermatitis			SIDER
44	Disease Progression			OFFSIDES
45	Disorientation			SIDER
46	Disseminated Intravascular Coagulation			OFFSIDES
47	Dizziness		11785593 15868998	CTD SIDER
48	Drowsiness			SIDER
49	Drug Dependence			SIDER
50	Drug exposure before pregnancy			OFFSIDES
51	Drug exposure during pregnancy			OFFSIDES
52	Drug toxicity			OFFSIDES
53	Dry skin			OFFSIDES
54	Dysphasia			OFFSIDES
55	Dystonia		2006748 9557916	CTD OFFSIDES
56	Electrocardiogram ST-T segment depression			OFFSIDES
57	Endotracheal intubation complication			SIDER
58	Epilepsy		16647582	CTD
59	Epistaxis			SIDER
60	Erythema			SIDER
61	Escherichia infection			OFFSIDES
62	Euphoric mood			SIDER
63	Fatigue			SIDER
64	Fatty Liver			OFFSIDES
65	Feeling abnormal			SIDER
66	Formication			OFFSIDES
67	General physical health deterioration			OFFSIDES
68	Glasgow coma scale			OFFSIDES
69	HELLP Syndrome			OFFSIDES
70	Headache			SIDER
71	Hemiplegia			OFFSIDES
72	Hyperalgesia		View details 11240090 11808827 12583865 16508403	CTD
73	Hypercapnia		9037435	CTD SIDER
74	Hyperkeratosis			OFFSIDES
75	Hyperparathyroidism			OFFSIDES
76	Hyperreflexia			OFFSIDES
77	Hypersensitivity			SIDER
78	Hyperventilation			OFFSIDES
79	Hypocoagulable state			OFFSIDES
80	Hypotension		2968185 9037435 11251433	CTD SIDER
81	Hypoxia		9037435 15868998	CTD OFFSIDES
82	Immobile			OFFSIDES
83	Infection			OFFSIDES
84	Injection site pain			SIDER
85	Intraoperative Awareness		3919524	CTD
86	Intraoperative Complications		15595588	CTD
87	Labile blood pressure			OFFSIDES
88	Laryngospasm			SIDER
89	Leukoencephalopathy			OFFSIDES
90	Microstomia			OFFSIDES
91	Muscle Rigidity		View details 1632539 2531560 2569282 2575721 3008595 3096494 3115150 3125768 3129743 3919609 7880510 8949692 9286888	CTD SIDER
92	Myocardial Ischemia		10051940	CTD
93	Myoclonic Epilepsy			OFFSIDES
94	Myoclonus		View details 2531560 6148025 9793810 10513376	CTD SIDER
95	Myotonia			OFFSIDES
96	Optic Disc Edema			OFFSIDES
97	Pain, Postoperative		15595588	CTD
98	Pain		View details 1514343 1773364 2311157 6148025 8130055 8623944 8702050 8778746 8949692 9620514 11240090 11465562 11808827 12583865 12879672 15590252 15983465 16508403 16563328 17159759 19542104	CTD SIDER
99	Palmar erythema			OFFSIDES
100	Paranasal sinus hypersecretion			OFFSIDES
101	Pelvic mass			OFFSIDES
102	Piloerection			OFFSIDES
103	Postoperative Complications		2311153	CTD
104	Postoperative Nausea and Vomiting		3919609	CTD
105	Pruritus			SIDER
106	Pulmonary function test decreased			SIDER
107	Pulmonary vascular disorder			OFFSIDES
108	Respiratory Depression			SIDER
109	Respiratory Insufficiency		2311153 9037435 16563328	CTD
110	Respiratory arrest			SIDER
111	Scleroderma			OFFSIDES
112	Screaming			OFFSIDES
113	Seizures		1443714 9043745 11240593	CTD
114	Shivering			SIDER
115	Sick Sinus Syndrome		2065427	CTD
116	Sinus Arrest, Cardiac		2505629 3137840	CTD
117	Skin test positive			OFFSIDES
118	Somnolence			SIDER
119	Staring			OFFSIDES
120	Tachycardia		15167427	CTD SIDER
121	Tetany			OFFSIDES
122	Unresponsive to stimuli			SIDER
123	Urticaria			SIDER
124	Varicose vein operation			OFFSIDES
125	Vascular pain			SIDER
126	Vein pain			SIDER
127	Ventricular Fibrillation			OFFSIDES
128	Visual Impairment			SIDER
129	Visual disturbance			SIDER
130	Vomiting			SIDER
131	nervous system disorder			SIDER

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