MetaADEDB 2.0 @ LMMD
apraclonidine
(IEJXVRYNEISIKR-UHFFFAOYSA-N)
Structure
SMILES
Nc1cc(Cl)c(c(c1)Cl)NC1=NCCN1
Type(s)
Approved
ATC code(s)
S01EA03
Molecular Formula:
C9H10Cl2N4
Molecular Weight:
245.108
Log P:
2.3653
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
3
TPSA:
62.44
CAS Number(s):
66711-21-5
Synonym(s)
1.
apraclonidine
2.
2-(4-amino-2,6-dichloro)phenyliminoimidazolidine
3.
4-aminoclonidine
4.
ALO 2145
5.
ALO-2145
6.
Iopidine
7.
Iopimax
8.
apraclonidine hydrochloride
9.
p-aminoclonidine
10.
para-aminoclonidine
External Link(s)
MeSHC016986
PubChem Compound2216
BindingDB50021812
81926
ChEBI2788
CHEMBLCHEMBL647
DrugBankDB00964
DrugCentral229
IUPHAR/BPS Guide to PHARMACOLOGY7117
KEGGcpd:C07668
dr:D07461
Therapeutic Target DatabaseD0MT0M
ZINC20231
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1PallorFAERS: 6SIDER
US FAERS
2BradycardiaFAERS: 516189050
17572343		CTD
SIDER
US FAERS
3LethargyFAERS: 417572343CTD
US FAERS
4SomnolenceFAERS: 4SIDER
US FAERS
5Unresponsive to stimuliFAERS: 4US FAERS
6Eye irritationFAERS: 3SIDER
US FAERS
7Eye painFAERS: 3SIDER
US FAERS
8Drug ineffectiveFAERS: 2US FAERS
9HypoxiaFAERS: 2US FAERS
10Incorrect dose administeredFAERS: 2US FAERS
11AbasiaFAERS: 1US FAERS
12Accidental drug intake by childFAERS: 1US FAERS
13Accidental exposure to productFAERS: 1US FAERS
14BlindnessFAERS: 1US FAERS
15Cardiac ArrestFAERS: 1US FAERS
16Contraindicated product administeredFAERS: 1US FAERS
17Depressed Level of ConsciousnessFAERS: 1US FAERS
18DiplopiaFAERS: 1US FAERS
19Drug administration errorFAERS: 1US FAERS
20HypersensitivityFAERS: 1SIDER
US FAERS
21HypoventilationFAERS: 1US FAERS
22Negative thoughtsFAERS: 1US FAERS
23Ocular discomfortFAERS: 1SIDER
US FAERS
24PhotophobiaFAERS: 1SIDER
US FAERS
25Product quality issueFAERS: 1US FAERS
26Retinal pigment epitheliopathyFAERS: 1US FAERS
27RhinitisFAERS: 1SIDER
US FAERS
28SymblepharonFAERS: 1US FAERS
29TrichiasisFAERS: 1US FAERS
30Abdominal PainSIDER
31Abdominal discomfortSIDER
32Abnormal visionSIDER
33Anisocoria16808679
17572343		CTD
34AstheniaSIDER
35AsthmaSIDER
36BlanchingSIDER
37BlepharitisSIDER
38BlepharoconjunctivitisSIDER
39BlepharospasmSIDER
40Chest PainSIDER
41Conjunctival Diseases8590259CTD
42ConjunctivitisSIDER
43Consciousness Disorders16189050CTD
44ConstipationSIDER
45Corneal Diseases8590259CTD
46Corneal erosionSIDER
47DermatitisSIDER
48DiscomfortSIDER
49Disturbance in sexual arousalSIDER
50DizzinessSIDER
51DysgeusiaSIDER
52EndophthalmitisSIDER
53Entropion8590259CTD
54ErythemaSIDER
55Eyelid Diseases18454417CTD
56Eyelid margin crustingSIDER
57FatigueSIDER
58Feeling abnormalSIDER
59Foreign body sensation in eyesSIDER
60Gastrointestinal PainSIDER
61Glaucoma, Open-Angle10457699CTD
62HeadacheSIDER
63Horner Syndrome17572343CTD
64Hypotension16189050CTD
65InfectionSIDER
66InfestationSIDER
67InflammationSIDER
68KeratitisSIDER
69KeratopathySIDER
70LacrimationSIDER
71MalaiseSIDER
72MicrohemorrhageSIDER
73Musculoskeletal discomfortSIDER
74MyalgiaSIDER
75Mydriasis8590259
8720243		CTD
SIDER
76NasopharyngitisSIDER
77NauseaSIDER
78NervousnessSIDER
79Ocular Hypertension16189050
17572343		CTD
80Ocular Hypotension8590259CTD
81Pain, Postoperative15218410CTD
82PainSIDER
83PalpitationsSIDER
84PharyngitisSIDER
85PresyncopeSIDER
86PruritusSIDER
87Respiratory Insufficiency17572343CTD
88ScabSIDER
89SyncopeSIDER
90TensionSIDER
91Throat irritationSIDER
92Upset stomachSIDER
93Vasodilation procedureSIDER
94VasodilationSIDER
95Vision Disorders1347973CTD
96Visual ImpairmentSIDER
97Vital dye staining cornea presentSIDER
98VomitingSIDER
99Xerostomia1347973CTD
100nervous system disorderSIDER
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