MetaADEDB 2.0 @ LMMD
Flumazenil
(OFBIFZUFASYYRE-UHFFFAOYSA-N)
Structure
SMILES
CCOC(=O)c1ncn2c1CN(C)C(=O)c1c2ccc(c1)F
Type(s)
Approved
ATC code(s)
V03AB25
Molecular Formula:
C15H14FN3O3
Molecular Weight:
303.288
Log P:
1.7116
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
0
TPSA:
64.43
CAS Number(s):
78755-81-4
Synonym(s)
1.
Flumazenil
2.
Flumazepil
3.
Anexate
4.
Lanexat
5.
Ro 15-1788
6.
Romazicon
7.
Ro 15 1788
8.
Ro 151788
External Link(s)
MeSHD005442
PubChem Compound3373
BindingDB26263
26264
ChEBI5103
CHEMBLCHEMBL407
DrugBankDB01205
DrugCentral1195
IUPHAR/BPS Guide to PHARMACOLOGY4192
4367
KEGGcpd:C07825
dr:D00697
Therapeutic Target DatabaseD0D5GD
D02MTS
ZINC1464
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 3US FAERS
2Medication ErrorFAERS: 3US FAERS
3ShockFAERS: 3US FAERS
4Disease ProgressionFAERS: 2US FAERS
5Product label issueFAERS: 2US FAERS
6Accidental exposure to productFAERS: 1US FAERS
7AgitationFAERS: 1SIDER
US FAERS
8AnxietyFAERS: 1SIDER
US FAERS
9BruxismFAERS: 1US FAERS
10Chest discomfortFAERS: 1US FAERS
11ChillsFAERS: 1SIDER
US FAERS
12Circumstance or information capable of leading to medication errorFAERS: 1OFFSIDES
US FAERS
13Drug effect incompleteFAERS: 1US FAERS
14Drug screen positiveFAERS: 1US FAERS
15ErythemaFAERS: 1SIDER
US FAERS
16Exposure via inhalationFAERS: 1US FAERS
17HeadacheFAERS: 19332625CTD
SIDER
US FAERS
18Incorrect route of drug administrationFAERS: 1US FAERS
19NauseaFAERS: 11286498
9332625		CTD
SIDER
US FAERS
20No adverse eventFAERS: 1US FAERS
21Oropharyngeal painFAERS: 1OFFSIDES
US FAERS
22PalpitationsFAERS: 1SIDER
US FAERS
23PneumothoraxFAERS: 1US FAERS
24SomnolenceFAERS: 1SIDER
US FAERS
25Venous InjuryFAERS: 1US FAERS
26Ventricular FibrillationFAERS: 1US FAERS
27Wrong drug administeredFAERS: 1US FAERS
28Abnormal visionSIDER
29AbuseOFFSIDES
30AcidosisOFFSIDES
31Actinic keratosisOFFSIDES
32AgraphiaOFFSIDES
33Akathisia, Drug-Induced9415834CTD
34Alanine Aminotransferase IncreasedOFFSIDES
35Alcoholic IntoxicationOFFSIDES
36Altered state of consciousnessOFFSIDES
37Amnesia, Anterograde2502317
3092849
3105566		CTD
38Amnesia

View details

1286497
1803833
2223335
3135223
8235775
9467187
 		CTD
39AngerSIDER
40AnisocoriaOFFSIDES
41Anxiety attackSIDER
42Apnea

View details

2005661
8319721
9512213
10536545
 		CTD
43AppendectomyOFFSIDES
44AppendicitisOFFSIDES
45ArteriosclerosisOFFSIDES
46AsphyxiaSIDER
47AstheniaSIDER
48Ataxia9987027
12404077		CTD
SIDER
49Atrial tachycardiaOFFSIDES
50AuraOFFSIDES
51Bilirubin conjugated increasedOFFSIDES
52Blood albumin decreasedOFFSIDES
53Bradycardia3683766
9332625		CTD
OFFSIDES
SIDER
54BronchopneumoniaOFFSIDES
55Cardiac HypertrophyOFFSIDES
56Cardiovascular DeconditioningOFFSIDES
57Catalepsy6208949CTD
58CausalgiaOFFSIDES
59Central venous catheter removalOFFSIDES
60Cervical laser therapyOFFSIDES
61Chest PainSIDER
62Cognition Disorders2116156
12496752		CTD
63Completed SuicideOFFSIDES
64Confusion2502317
3092849
11737177		CTD
65Congenital diaphragmatic herniaOFFSIDES
66Consciousness Disorders18418024CTD
67CryingSIDER
68DeafnessSIDER
69Delirium12609649
18460520		CTD
SIDER
70DemyelinationOFFSIDES
71Dental abscessOFFSIDES
72Dental cariesOFFSIDES
73DependenceSIDER
74Depressed Level of ConsciousnessOFFSIDES
SIDER
75Depressed moodSIDER
76DermatitisSIDER
77DiplopiaSIDER
78DiscomfortSIDER
79Disorders of Excessive Somnolence11422855
26415617		CTD
80Disruptive, Impulse Control, and Conduct Disorders6093179CTD
81Dizziness1286497
9332625
18418024		CTD
SIDER
82DrowsinessOFFSIDES
SIDER
83Drug abuseSIDER
84Drug exposure during pregnancyOFFSIDES
85Drug withdrawal syndromeSIDER
86DysphoniaSIDER
87Dystonia2108778CTD
88DysuriaOFFSIDES
89Emotional distressOFFSIDES
90Endodontic procedureOFFSIDES
91Epilepsy8325278CTD
SIDER
92Euphoric moodSIDER
93FatigueSIDER
94Feeling ColdSIDER
95Feeling abnormalSIDER
96Flank PainOFFSIDES
97FlushingSIDER
98Gastric ulcerOFFSIDES
99GranulocytosisOFFSIDES
100Heart Block1679653CTD
101Hepatic Encephalopathy2575692
18719775		CTD
102Hepatic siderosisOFFSIDES
103HerniaOFFSIDES
104HyperacusisSIDER
105Hyperalgesia10323274CTD
106HypersensitivitySIDER
107HyperventilationSIDER
108Hypotension3683766
9332625		CTD
SIDER
109Hypoventilation9332625CTD
110Hypoxia9332625CTD
OFFSIDES
111IncoherentOFFSIDES
112InfectionOFFSIDES
113Injection Site ReactionSIDER
114Injection site painSIDER
115Intentional misuseOFFSIDES
116Intercepted drug administration errorOFFSIDES
117Intestinal PerforationOFFSIDES
118Liver transplant rejectionOFFSIDES
119Loose toothOFFSIDES
120MalaiseSIDER
121Mental disorders1811430CTD
122Metabolic acidosisOFFSIDES
123Mood swingsSIDER
124Motor Skills Disorders26415617CTD
125Muscle Rigidity6809488CTD
126Muscle hypotonia8319721CTD
127Myocardial fibrosisOFFSIDES
128Myoclonus11349753CTD
129NervousnessSIDER
130Neutropenic sepsisOFFSIDES
131OverdoseOFFSIDES
132Pain9332625CTD
OFFSIDES
SIDER
133Panic Disorder

View details

2171449
9694026
10723632
12496752
19494738
 		CTD
SIDER
134ParanoiaSIDER
135PeritonitisOFFSIDES
136Poisoning1980218
11083957
15214628		CTD
137Postoperative Nausea and Vomiting3098131CTD
138Prenatal Exposure Delayed Effects2840561CTD
139Procedural nauseaOFFSIDES
140Procedural vomitingOFFSIDES
141Pruritus9332625CTD
SIDER
142Psychomotor Agitation11737177CTD
143Psychomotor Disorders2505632CTD
144PyelonephritisOFFSIDES
145RednessSIDER
146Renal cystOFFSIDES
147Renal tubular necrosisOFFSIDES
148Respiratory Insufficiency1391357CTD
149RhinitisOFFSIDES
150ScotomaSIDER
151Seizures

View details

1329401
1334454
1366108
1453872
1458953
1943471
1946580
2217501
2219507
2510872
2779359
3575358
3926518
6423394
6809488
7651879
7696723
8087716
8135424
8782029
8924153
8937022
15214628
16628099
18466897
19500521
 		CTD
152Septic ShockOFFSIDES
153ShiveringSIDER
154Sialorrhea6809488CTD
155Snoring10536545CTD
156SoporOFFSIDES
157Squamous cell carcinoma of skinOFFSIDES
158Status Epilepticus8162392CTD
OFFSIDES
159StuporSIDER
160Substance Withdrawal Syndrome

View details

1327709
1523281
1557510
2838131
3093182
3137588
6809488
7899256
9023073
10591888
 		CTD
161Supraventricular tachycardiaSIDER
162SweatingSIDER
163Tachycardia, Ventricular2510872CTD
164Tachycardia9415834CTD
SIDER
165TensionSIDER
166TetanySIDER
167ThrombophlebitisSIDER
168TinnitusSIDER
169Tooth ExtractionOFFSIDES
170Tremor6809488CTD
SIDER
171Unresponsive to stimuliOFFSIDES
172UrticariaSIDER
173Vasodilation procedureSIDER
174VasodilationSIDER
175VertigoSIDER
176Visual ImpairmentSIDER
177Voice Disorders9332625CTD
178Vomiting1286498
9332625		CTD
SIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.