Levobupivacaine
(LEBVLXFERQHONN-INIZCTEOSA-N)
Structure
- SMILES
- CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C
- Type(s)
- Approved; Investigational
- ATC code(s)
- N01BB10
- Molecular Formula:
- C18H28N2O
- Molecular Weight:
- 288.428
- Log P:
- 3.9074
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 1
- TPSA:
- 32.34
- CAS Number(s):
- 18010-40-7; 27262-47-1
Synonym(s)
1.
Levobupivacaine
2.
Chirocaine
3.
Levobupivacaine Hydrochloride
External Link(s)
| MeSH | D000077554 |
| PubChem Compound | 92253 |
| BindingDB | 50417951 50350791 |
| ChEBI | 6149 |
| CHEMBL | CHEMBL1201193 |
| DrugBank | DB01002 |
| DrugCentral | 4 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 7211 |
| KEGG | cpd:C07887 dr:D08116 |
| Therapeutic Target Database | D09QUQ |
| ZINC | 1530812 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Cardiac Arrest | FAERS: 3 | US FAERS | |
| 2 | Drug administration error | FAERS: 3 | US FAERS | |
| 3 | Respiratory arrest | FAERS: 3 | US FAERS | |
| 4 | Limb discomfort | FAERS: 2 | US FAERS | |
| 5 | Toxicity to various agents | FAERS: 2 | US FAERS | |
| 6 | nervous system disorder | FAERS: 2 | US FAERS | |
| 7 | Idiosyncratic drug reaction | FAERS: 1 | US FAERS | |
| 8 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 9 | Bradycardia | 19050087 | CTD | |
| 10 | Cardiovascular Diseases | 17448066 18278394 24091473 | CTD | |
| 11 | Horner Syndrome | 18950347 | CTD | |
| 12 | Hypotension | 11133597 19189982 19412143 | CTD | |
| 13 | Labor Pain | CTD | ||
| 14 | Pain, Postoperative | CTD | ||
| 15 | Postoperative Nausea and Vomiting | 19189982 | CTD | |
| 16 | Pruritus | 19189982 | CTD | |
| 17 | Respiratory Insufficiency | 12818949 | CTD | |
| 18 | Seizures | CTD | ||
| 19 | Ventricular Fibrillation | 11049891 | CTD |
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