MetaADEDB 2.0 @ LMMD
Methohexital
(NZXKDOXHBHYTKP-UHFFFAOYSA-N)
Structure
SMILES
CCC#CC(C1(CC=C)C(=O)NC(=O)N(C1=O)C)C
Type(s)
Approved
ATC code(s)
N01AF01; N05CA15; N05CB01
Molecular Formula:
C14H18N2O3
Molecular Weight:
262.304
Log P:
1.5733
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
1
TPSA:
66.48
CAS Number(s):
151-83-7; 115621-33-5
Synonym(s)
1.
Methohexital
2.
Methohexitone
3.
Brevimytal Natrium
4.
Brevital
5.
Brietal
6.
Brietal-Sodium
7.
Methohexital Sodium
8.
Methohexital, Monosodium Salt
9.
Brietal Sodium
10.
Monosodium Salt Methohexital
11.
Natrium, Brevimytal
12.
Sodium, Methohexital
External Link(s)
MeSHD008723
PubChem Compound9034
ChEBI102216
CHEMBLCHEMBL7413
DrugBankDB00474
DrugCentral1748
IUPHAR/BPS Guide to PHARMACOLOGY7233
KEGGcpd:C07844
dr:D04985
Therapeutic Target DatabaseD0S8TD
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Respiratory FailureFAERS: 2US FAERS
2AgitationFAERS: 1SIDER
US FAERS
3BradycardiaFAERS: 1US FAERS
4Drug dispensing errorFAERS: 1US FAERS
5Drug ineffectiveFAERS: 1US FAERS
6Ejection Fraction DecreasedFAERS: 1US FAERS
7Incorrect dose administeredFAERS: 1US FAERS
8OliguriaFAERS: 1US FAERS
9Oral painFAERS: 1US FAERS
10Oropharyngeal painFAERS: 1US FAERS
11Pericardial effusionFAERS: 1US FAERS
12Product quality issueFAERS: 1US FAERS
13Sinus bradycardiaFAERS: 1US FAERS
14Abdominal PainSIDER
15Airway Obstruction7486084CTD
16Amnesia4564636CTD
17Anaphylactic shockSIDER
18AnxietySIDER
19Apnea

View details

2042766
4564636
6961534
8768153
 		CTD
20BronchospasmSIDER
21Cardiovascular insufficiencySIDER
22Chills5774518CTD
23Circulatory depressionSIDER
24DeliriumSIDER
25Epilepsy9701374CTD
26Erythema1015219CTD
SIDER
27Gastrointestinal PainSIDER
28HeadacheSIDER
29HyperkinesiaSIDER
30Hypersensitivity4508219
4508220		CTD
31Hypotension5115033CTD
SIDER
32Injection site painSIDER
33LaryngospasmSIDER
34Myoclonus5774518
9793810		CTD
35NauseaSIDER
36Opioid-Related Disorders10809268CTD
37Pain

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2782576
4564636
6741597
7030121
 		CTD
38PruritusSIDER
39Pulmonary function test decreasedSIDER
40Respiratory DepressionSIDER
41Respiratory Insufficiency5115033
8768153		CTD
42RhinitisSIDER
43Seizures

View details

697329
5001158
7156448
7212335
7653829
17049312
 		CTD
44ShockSIDER
45Status Epilepticus900462
5690286		CTD
46Tachycardia1015219CTD
SIDER
47Thrombophlebitis4897470
6741597		CTD
SIDER
48UrticariaSIDER
49VomitingSIDER
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