MetaADEDB 2.0 @ LMMD
Flupenthixol
(NJMYODHXAKYRHW-DVZOWYKESA-N)
Structure
SMILES
OCCN1CCN(CC1)CC/C=C\1/c2ccccc2Sc2c1cc(cc2)C(F)(F)F
Type(s)
Approved; Investigational; Withdrawn
ATC code(s)
N05AF01
Molecular Formula:
C23H25F3N2OS
Molecular Weight:
434.518
Log P:
4.4775
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
52.01
CAS Number(s):
2709-56-0; 53772-82-0
Synonym(s)
1.
Flupenthixol
2.
Emergil
3.
Fluanxol
4.
Flupentixol
5.
alpha-Flupenthixol
6.
cis-Flupenthixol
External Link(s)
MeSHD005475
PubChem Compound5281881
BindingDB85327
50240515
79172
ChEBI10454
CHEMBLCHEMBL54661
DrugBankDB00875
IUPHAR/BPS Guide to PHARMACOLOGY948
KEGGcpd:C11191
dr:D01044
ZINC29489118
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal Compartment SyndromeOFFSIDES
2Abnormal sleep-related eventOFFSIDES
3Abnormal visionOFFSIDES
4Accidental overdoseOFFSIDES
5AcidosisOFFSIDES
6Acute left ventricular failureOFFSIDES
7Alanine Aminotransferase IncreasedOFFSIDES
8Alcohol poisoningOFFSIDES
9Ammonia increasedOFFSIDES
10AmnesiaCanada Vigilance: 2Canada Vigilance
OFFSIDES
11AngerOFFSIDES
12Angle Closure GlaucomaOFFSIDES
13AnxietyOFFSIDES
14ApathyOFFSIDES
15Apparent deathOFFSIDES
16AsphyxiaOFFSIDES
17AtaxiaOFFSIDES
18Atrial tachycardiaOFFSIDES
19AuraOFFSIDES
20Basal Ganglia Diseases

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1091124
1407229
4944664
6844372
 		CTD
21Bipolar Disorder8211474
12457745		CTD
OFFSIDES
22BlepharoptosisOFFSIDES
23BlepharospasmOFFSIDES
24Blood creatine phosphokinase MB increasedOFFSIDES
25Blood creatine phosphokinase increasedOFFSIDES
26Blood pressure fluctuationOFFSIDES
27Blood sodiumOFFSIDES
28Blood testosterone decreasedCanada Vigilance: 1Canada Vigilance
29Blood uric acidOFFSIDES
30Brain Diseases1273164CTD
31BruxismOFFSIDES
32Carbon Monoxide PoisoningOFFSIDES
33Cardiac enzymes increasedOFFSIDES
34Chemotherapeutic drug level increasedOFFSIDES
35ChillsCanada Vigilance: 1Canada Vigilance
36Chorea709010CTD
37Chronic Obstructive Airway DiseaseOFFSIDES
38Cocaine-Related Disorders

View details

9741939
10481841
15306650
17505018
 		CTD
39Cogwheel RigidityOFFSIDES
40Completed SuicideOFFSIDES
41ConfabulationOFFSIDES
42CoprolaliaOFFSIDES
43CryingOFFSIDES
44CyanosisOFFSIDES
45Decreased LibidoOFFSIDES
46DependenceOFFSIDES
47Depressed moodOFFSIDES
48Depressive disorder773506CTD
49Diabetes MellitusCanada Vigilance: 1Canada Vigilance
50Diabetic NephropathyOFFSIDES
51DiarrheaOFFSIDES
52Diet refusalOFFSIDES
53Disease ProgressionOFFSIDES
54Disruptive, Impulse Control, and Conduct Disorders6813425
8097040		CTD
55Drug withdrawal syndromeCanada Vigilance: 1Canada Vigilance
56Dry skinOFFSIDES
57Dyskinesia, Drug-Induced9443657CTD
58DysmorphismOFFSIDES
59DysphasiaOFFSIDES
60Dysthymic DisorderOFFSIDES
61Dystonia6786609
11672942		CTD
62EcholaliaOFFSIDES
63Electrocardiogram poor R-wave progressionOFFSIDES
64EnterocolitisOFFSIDES
65Eosinophilic myocarditisOFFSIDES
66Erectile dysfunctionCanada Vigilance: 1Canada Vigilance
OFFSIDES
67ErysipelasOFFSIDES
68FatigueCanada Vigilance: 2Canada Vigilance
OFFSIDES
69Fatty Liver12934993CTD
OFFSIDES
70Feeling abnormalCanada Vigilance: 1Canada Vigilance
71Feeling of body temperature changeCanada Vigilance: 1Canada Vigilance
72FolliculitisOFFSIDES
73FormicationOFFSIDES
74FrustrationOFFSIDES
75Gamma-Glutamyltransferase IncreasedOFFSIDES
76Genital rashOFFSIDES
77Graft infectionOFFSIDES
78GranulomaOFFSIDES
79HeadacheCanada Vigilance: 1Canada Vigilance
80Hepatic necrosisOFFSIDES
81Heroin Dependence10481841CTD
82HiccoughOFFSIDES
83HyperreflexiaOFFSIDES
84HypokinesiaOFFSIDES
85HypoparathyroidismOFFSIDES
86HyporeflexiaOFFSIDES
87Impaired self-careOFFSIDES
88IncontinenceOFFSIDES
89Intention tremorOFFSIDES
90Intentional misuseOFFSIDES
91Intentional self-injuryOFFSIDES
92LacerationOFFSIDES
93LethargyOFFSIDES
94LeukoencephalopathyOFFSIDES
95Leukopenia neonatalOFFSIDES
96LymphocytosisOFFSIDES
97Lysosomal Storage Diseases28551711CTD
98MalaiseCanada Vigilance: 1Canada Vigilance
99Mental disorders2409454
16856516		CTD
100Mental impairmentOFFSIDES
101Morbid thoughtsOFFSIDES
102Movement Disorders709010CTD
103Multiple drug overdoseOFFSIDES
104Multiple drug overdose intentionalOFFSIDES
105Muscle hypertrophyOFFSIDES
106NauseaOFFSIDES
107NephrolithiasisOFFSIDES
108Neuroleptic Malignant Syndrome6428599CTD
OFFSIDES
109NocturiaOFFSIDES
110OverdoseOFFSIDES
111Paranoid Personality DisorderOFFSIDES
112Pericardial effusionOFFSIDES
113Poor quality sleepOFFSIDES
114Pressure of speechOFFSIDES
115Productive CoughOFFSIDES
116PsoriasisOFFSIDES
117Psychoses, Substance-Induced1407229CTD
118Psychotic Disorders6844372
15380868		CTD
119Quality of life decreasedCanada Vigilance: 1Canada Vigilance
120Respiratory Insufficiency6428599CTD
121Schizophrenia1091124
4944664
8055610		CTD
OFFSIDES
122Seizures8055610CTD
123Self MutilationOFFSIDES
124Sexual DysfunctionCanada Vigilance: 1Canada Vigilance
125SomnolenceCanada Vigilance: 2Canada Vigilance
126StaringOFFSIDES
127Sudden deathOFFSIDES
128Suprapubic painOFFSIDES
129Temperature regulation disorderOFFSIDES
130TetanyOFFSIDES
131TheftOFFSIDES
132Tongue bitingOFFSIDES
133Transaminases increasedOFFSIDES
134Troponin increasedOFFSIDES
135Urethral StenosisOFFSIDES
136Violence-related symptomOFFSIDES
137Weight Gain12934993CTD
OFFSIDES
138effusionOFFSIDES
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