Erythromycin Estolate
(AWMFUEJKWXESNL-JZBHMOKNSA-N)
Structure
- SMILES
- CCC(=O)O[C@H]1[C@@H](O[C@@H](C[C@@H]1N(C)C)C)O[C@@H]1[C@@H](C)[C@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@@H](C)C(=O)O[C@H](CC)[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]1(C)O)C)C)O)(C)O.CCCCCCCCCCCCOS(=O)(=O)O
- Molecular Formula:
- C52H97NO18S
- Molecular Weight:
- 1056.390
- Log P:
- 7.5540
- Hydrogen Bond Acceptor:
- 19
- Hydrogen Bond Donor:
- 5
- TPSA:
- 271.96
- CAS Number(s):
- 3521-62-8
Synonym(s)
1.
Erythromycin Estolate
2.
Erythromycin Propionate Dodecyl Sulfate
3.
Erythromycin Propionate Lauryl Sulfate
4.
Eromycin
5.
Erythromycin Propionate Monododecyl Sulfate
6.
Ilosone
7.
Lauromicina
8.
Estolate, Erythromycin
External Link(s)
| MeSH | D004918 |
| PubChem Compound | 441371 |
| BindingDB | 31688 |
| ChEBI | 4846 |
| CHEMBL | CHEMBL2218877 |
| KEGG | dr:D00851 cpd:C08031 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Vomiting | FAERS: 12 Canada Vigilance: 25 | Canada Vigilance US FAERS | |
| 2 | Nausea | FAERS: 7 Canada Vigilance: 12 | Canada Vigilance US FAERS | |
| 3 | Urticaria | FAERS: 7 Canada Vigilance: 11 | Canada Vigilance US FAERS | |
| 4 | Unevaluable event | FAERS: 4 | US FAERS | |
| 5 | Abdominal discomfort | FAERS: 3 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 6 | Hypersensitivity | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 7 | Erythema | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 8 | Pruritus | FAERS: 2 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 9 | Abasia | FAERS: 1 | US FAERS | |
| 10 | Abdominal Pain | FAERS: 1 Canada Vigilance: 24 | Canada Vigilance US FAERS | |
| 11 | Dehydration | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Dizziness | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Drug ineffective | FAERS: 1 | US FAERS | |
| 14 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 15 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 16 | Headache | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 17 | Hepatic Infection | FAERS: 1 | US FAERS | |
| 18 | Hepatitis | FAERS: 1 Canada Vigilance: 11 | Canada Vigilance US FAERS | |
| 19 | Pyloric Stenosis | FAERS: 1 | US FAERS | |
| 20 | Rash erythematous | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 21 | Stomatitis | FAERS: 1 | US FAERS | |
| 22 | Syncope | FAERS: 1 | US FAERS | |
| 23 | Tremor | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 24 | Vaginal lesion | FAERS: 1 | US FAERS | |
| 25 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 26 | Alanine Aminotransferase Increased | Canada Vigilance: 4 | Canada Vigilance | |
| 27 | Angioedema | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Anxiety | Canada Vigilance: 2 | Canada Vigilance | |
| 29 | Aspartate Aminotransferase Increased | Canada Vigilance: 7 | Canada Vigilance | |
| 30 | Asthenia | Canada Vigilance: 3 | Canada Vigilance | |
| 31 | Asthma | Canada Vigilance: 2 | Canada Vigilance | |
| 32 | Back Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Biliary Colic | Canada Vigilance: 2 | Canada Vigilance | |
| 34 | Blood alkaline phosphatase increased | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Blood lactate dehydrogenase increased | Canada Vigilance: 1 | Canada Vigilance | |
| 36 | Chemical and Drug Induced Liver Injury | CTD | ||
| 37 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 38 | Chest discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 39 | Chills | Canada Vigilance: 3 | Canada Vigilance | |
| 40 | Cholangiolitis | Canada Vigilance: 1 | Canada Vigilance | |
| 41 | Cholangitis | Canada Vigilance: 1 | Canada Vigilance | |
| 42 | Cholestasis | Canada Vigilance: 2 | 572556 24412560 | CTD Canada Vigilance |
| 43 | Chromaturia | Canada Vigilance: 1 | Canada Vigilance | |
| 44 | Diplopia | Canada Vigilance: 1 | Canada Vigilance | |
| 45 | Dysgeusia | Canada Vigilance: 1 | Canada Vigilance | |
| 46 | Eczema | Canada Vigilance: 1 | Canada Vigilance | |
| 47 | Enzyme abnormality | Canada Vigilance: 2 | Canada Vigilance | |
| 48 | Eosinophilia | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Fatigue | Canada Vigilance: 1 | Canada Vigilance | |
| 50 | Flushing | Canada Vigilance: 2 | Canada Vigilance | |
| 51 | Gastroenteritis | Canada Vigilance: 1 | Canada Vigilance | |
| 52 | Hepatitis A | Canada Vigilance: 1 | Canada Vigilance | |
| 53 | Hepatomegaly | Canada Vigilance: 1 | Canada Vigilance | |
| 54 | Hypotension | Canada Vigilance: 1 | Canada Vigilance | |
| 55 | Lethargy | Canada Vigilance: 2 | Canada Vigilance | |
| 56 | Leukocytosis | Canada Vigilance: 1 | Canada Vigilance | |
| 57 | Mydriasis | Canada Vigilance: 1 | Canada Vigilance | |
| 58 | Pain | Canada Vigilance: 6 | Canada Vigilance | |
| 59 | Palpitations | Canada Vigilance: 1 | Canada Vigilance | |
| 60 | Pancreatitis | Canada Vigilance: 2 | Canada Vigilance | |
| 61 | Pharyngitis | Canada Vigilance: 1 | Canada Vigilance | |
| 62 | Product administration error | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 64 | Shock | Canada Vigilance: 2 | Canada Vigilance | |
| 65 | Somnolence | Canada Vigilance: 1 | Canada Vigilance | |
| 66 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 67 | Tachycardia | Canada Vigilance: 2 | Canada Vigilance | |
| 68 | Torticollis | Canada Vigilance: 1 | Canada Vigilance | |
| 69 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 70 | jaundice | Canada Vigilance: 13 | Canada Vigilance | |
| 71 | pseudomembranous colitis | Canada Vigilance: 1 | Canada Vigilance |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120269
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.