Ceftriaxone
(YOBPSXOHCHDCMU-IXIFSOOLSA-M)
Structure
- SMILES
- CO/N=C(\c1csc(n1)N)/C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])CSc1nc(=O)c(=O)[nH]n1C.[Na+]
- Molecular Formula:
- C18H17N8NaO7S3
- Molecular Weight:
- 576.562
- Log P:
- -2.0360
- Hydrogen Bond Acceptor:
- 17
- Hydrogen Bond Donor:
- 3
- TPSA:
- 296.63
- CAS Number(s):
- 74578-69-1; 104376-79-6; 958633-51-7
Synonym(s)
1.
Ceftriaxone
2.
Benaxona
3.
Cefatriaxone
4.
Cefaxona
5.
Ceftrex
6.
Ceftriaxon
7.
Ceftriaxon Curamed
8.
Ceftriaxon Hexal
9.
Ceftriaxona Andreu
10.
Ceftriaxona LDP Torlan
11.
Ceftriaxone Irex
12.
Ceftriaxone Sodium
13.
Ceftriaxone Sodium, Anhydrous
14.
Ceftriaxone, Disodium Salt
15.
Ceftriaxone, Disodium Salt, Hemiheptahydrate
16.
Lendacin
17.
Longacef
18.
Longaceph
19.
Ro 13-9904
20.
Ro-13-9904
21.
Ro13-9904
22.
Rocefalin
23.
Rocefin
24.
Rocephin
25.
Rocephine
26.
Tacex
27.
Terbac
28.
Anhydrous Ceftriaxone Sodium
29.
Ro 13 9904
30.
Ro 139904
31.
Ro13 9904
32.
Ro139904
External Link(s)
| MeSH | D002443 |
| PubChem Compound | 23709629 |
| CHEMBL | CHEMBL1697718 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Cholelithiasis | FAERS: 39 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Choreoathetosis | FAERS: 14 | US FAERS | |
| 3 | Altered state of consciousness | FAERS: 13 | US FAERS | |
| 4 | Anaphylactic shock | FAERS: 13 | US FAERS | |
| 5 | Tachycardia | FAERS: 12 | US FAERS | |
| 6 | Urticaria | FAERS: 12 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 7 | Drug ineffective | FAERS: 10 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 8 | Shock | FAERS: 10 | US FAERS | |
| 9 | Clostridium difficile infection | FAERS: 9 | US FAERS | |
| 10 | Erythema | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 11 | Hypotension | FAERS: 9 | US FAERS | |
| 12 | Respiratory Failure | FAERS: 9 | US FAERS | |
| 13 | Hypersensitivity | FAERS: 8 | US FAERS | |
| 14 | Pruritus | FAERS: 8 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 15 | Cardiac Arrest | FAERS: 6 | US FAERS | |
| 16 | Expired product administered | FAERS: 6 | US FAERS | |
| 17 | Nausea | FAERS: 6 | US FAERS | |
| 18 | Abdominal Pain | FAERS: 5 | US FAERS | |
| 19 | Agranulocytosis | FAERS: 5 | US FAERS | |
| 20 | Cholecystitis | FAERS: 5 | US FAERS | |
| 21 | Drug specific antibody present | FAERS: 5 | US FAERS | |
| 22 | Neurodermatitis | FAERS: 5 | US FAERS | |
| 23 | Oropharyngeal pain | FAERS: 5 | US FAERS | |
| 24 | Pallor | FAERS: 5 | US FAERS | |
| 25 | Thrombocytopenia | FAERS: 5 | US FAERS | |
| 26 | Vomiting | FAERS: 5 | US FAERS | |
| 27 | Acute kidney injury | FAERS: 4 | US FAERS | |
| 28 | Cholangitis | FAERS: 4 | US FAERS | |
| 29 | Eosinophilia | FAERS: 4 | US FAERS | |
| 30 | Medication Error | FAERS: 4 | US FAERS | |
| 31 | Alanine Aminotransferase Increased | FAERS: 3 | US FAERS | |
| 32 | Alcohol Intolerance | FAERS: 3 | US FAERS | |
| 33 | Ascites | FAERS: 3 | US FAERS | |
| 34 | Aspartate Aminotransferase Increased | FAERS: 3 | US FAERS | |
| 35 | Back Pain | FAERS: 3 | US FAERS | |
| 36 | Biliary Colic | FAERS: 3 | US FAERS | |
| 37 | Bronchospasm | FAERS: 3 | US FAERS | |
| 38 | Chest discomfort | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 39 | Cyanosis | FAERS: 3 | US FAERS | |
| 40 | Depressed Level of Consciousness | FAERS: 3 | US FAERS | |
| 41 | Disseminated Intravascular Coagulation | FAERS: 3 | US FAERS | |
| 42 | Hepatitis | FAERS: 3 | US FAERS | |
| 43 | Hydronephrosis | FAERS: 3 | US FAERS | |
| 44 | Injection site pain | FAERS: 3 | US FAERS | |
| 45 | Malaise | FAERS: 3 | US FAERS | |
| 46 | No adverse event | FAERS: 3 | US FAERS | |
| 47 | Overdose | FAERS: 3 | US FAERS | |
| 48 | Pseudocholelithiasis | FAERS: 3 | US FAERS | |
| 49 | Throat irritation | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 50 | Acidosis | FAERS: 2 | US FAERS | |
| 51 | Ageusia | FAERS: 2 | US FAERS | |
| 52 | Anuria | FAERS: 2 | US FAERS | |
| 53 | Blood creatinine increased | FAERS: 2 | US FAERS | |
| 54 | Bradycardia | FAERS: 2 | US FAERS | |
| 55 | Chest Pain | FAERS: 2 | US FAERS | |
| 56 | Chills | FAERS: 2 | US FAERS | |
| 57 | Disorientation | FAERS: 2 | US FAERS | |
| 58 | Drug resistance | FAERS: 2 | US FAERS | |
| 59 | Dysgeusia | FAERS: 2 | US FAERS | |
| 60 | Dysphonia | FAERS: 2 | US FAERS | |
| 61 | Flushing | FAERS: 2 | US FAERS | |
| 62 | Gamma-Glutamyltransferase Increased | FAERS: 2 | US FAERS | |
| 63 | Hip Dysplasia | FAERS: 2 | US FAERS | |
| 64 | Hydrocephalus | FAERS: 2 | US FAERS | |
| 65 | Infantile apnoeic attack | FAERS: 2 | US FAERS | |
| 66 | Lethargy | FAERS: 2 | US FAERS | |
| 67 | Metabolic acidosis | FAERS: 2 | US FAERS | |
| 68 | Nephrolithiasis | FAERS: 2 | US FAERS | |
| 69 | Neutropenia | FAERS: 2 | US FAERS | |
| 70 | Pathogen resistance | FAERS: 2 | US FAERS | |
| 71 | Petechiae | FAERS: 2 | US FAERS | |
| 72 | Pneumonia | FAERS: 2 | US FAERS | |
| 73 | Product label issue | FAERS: 2 | US FAERS | |
| 74 | Product reconstitution quality issue | FAERS: 2 | US FAERS | |
| 75 | Psychomotor skills impaired | FAERS: 2 | US FAERS | |
| 76 | Restlessness | FAERS: 2 | US FAERS | |
| 77 | Sepsis | FAERS: 2 | US FAERS | |
| 78 | Status Epilepticus | FAERS: 2 | US FAERS | |
| 79 | Swelling | FAERS: 2 | US FAERS | |
| 80 | Syncope | FAERS: 2 | US FAERS | |
| 81 | Unresponsive to stimuli | FAERS: 2 | US FAERS | |
| 82 | Urinary Incontinence | FAERS: 2 | US FAERS | |
| 83 | Wheezing | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 84 | jaundice | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 85 | Abdominal rigidity | FAERS: 1 | US FAERS | |
| 86 | Angioedema | FAERS: 1 | US FAERS | |
| 87 | Anoxia | FAERS: 1 | US FAERS | |
| 88 | Anxiety | FAERS: 1 | US FAERS | |
| 89 | Apallic syndrome | FAERS: 1 | US FAERS | |
| 90 | Aphasia | FAERS: 1 | US FAERS | |
| 91 | Application site pain | FAERS: 1 | US FAERS | |
| 92 | Arthralgia | FAERS: 1 | US FAERS | |
| 93 | Asthenia | FAERS: 1 | US FAERS | |
| 94 | Biliary dilatation | FAERS: 1 | US FAERS | |
| 95 | Blindness | FAERS: 1 | US FAERS | |
| 96 | Blood albumin decreased | FAERS: 1 | US FAERS | |
| 97 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 98 | Blood lactate dehydrogenase increased | FAERS: 1 | US FAERS | |
| 99 | Blood triglycerides increased | FAERS: 1 | US FAERS | |
| 100 | Blood urea increased | FAERS: 1 | US FAERS | |
| 101 | Cerebral disorder | FAERS: 1 | US FAERS | |
| 102 | Choking sensation | FAERS: 1 | US FAERS | |
| 103 | Cholecystitis infective | FAERS: 1 | US FAERS | |
| 104 | Cholestasis | FAERS: 1 | US FAERS | |
| 105 | Cold sweat | FAERS: 1 | US FAERS | |
| 106 | Cystostomy | FAERS: 1 | US FAERS | |
| 107 | Dehydration | FAERS: 1 | US FAERS | |
| 108 | Delirium | FAERS: 1 | US FAERS | |
| 109 | Dyslalia | FAERS: 1 | US FAERS | |
| 110 | Ecchymosis | FAERS: 1 | US FAERS | |
| 111 | Ectropion | FAERS: 1 | US FAERS | |
| 112 | Electrocardiogram abnormal | FAERS: 1 | US FAERS | |
| 113 | Enteritis | FAERS: 1 | US FAERS | |
| 114 | Enterococcal infection | FAERS: 1 | US FAERS | |
| 115 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 116 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 117 | Flank Pain | FAERS: 1 | US FAERS | |
| 118 | Gait inability | FAERS: 1 | US FAERS | |
| 119 | Gallbladder necrosis | FAERS: 1 | US FAERS | |
| 120 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 121 | Hemiplegia | FAERS: 1 | US FAERS | |
| 122 | Histiocytosis haematophagic | FAERS: 1 | US FAERS | |
| 123 | Hypertensive crisis | FAERS: 1 | US FAERS | |
| 124 | Hypoxia | FAERS: 1 | US FAERS | |
| 125 | Ileus | FAERS: 1 | US FAERS | |
| 126 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 127 | Inflammation | FAERS: 1 | US FAERS | |
| 128 | Infusion Site Extravasation | FAERS: 1 | US FAERS | |
| 129 | Infusion site pain | FAERS: 1 | US FAERS | |
| 130 | Infusion site swelling | FAERS: 1 | US FAERS | |
| 131 | Injection site erythema | FAERS: 1 | US FAERS | |
| 132 | Injection site mass | FAERS: 1 | US FAERS | |
| 133 | Injection site pruritus | FAERS: 1 | US FAERS | |
| 134 | Intestinal Obstruction | FAERS: 1 | US FAERS | |
| 135 | Lip pruritus | FAERS: 1 | US FAERS | |
| 136 | Lip swelling | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 137 | Lung Abscess | FAERS: 1 | US FAERS | |
| 138 | Maternal exposure during pregnancy | FAERS: 1 | US FAERS | |
| 139 | Maternal exposure timing unspecified | FAERS: 1 | US FAERS | |
| 140 | Mental status changes | FAERS: 1 | US FAERS | |
| 141 | Microcephaly | FAERS: 1 | US FAERS | |
| 142 | Multi-organ disorder | FAERS: 1 | US FAERS | |
| 143 | Myalgia | FAERS: 1 | US FAERS | |
| 144 | Myoclonic Epilepsy | FAERS: 1 | US FAERS | |
| 145 | Nephrogenic Diabetes Insipidus | FAERS: 1 | US FAERS | |
| 146 | Nephrotic Syndrome | FAERS: 1 | US FAERS | |
| 147 | Night sweats | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 148 | Oliguria | FAERS: 1 | US FAERS | |
| 149 | Oral pruritus | FAERS: 1 | US FAERS | |
| 150 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 151 | Pain | FAERS: 1 | US FAERS | |
| 152 | Palpitations | FAERS: 1 | US FAERS | |
| 153 | Pancreatitis | FAERS: 1 | US FAERS | |
| 154 | Pancytopenia | FAERS: 1 | US FAERS | |
| 155 | Pemphigus | FAERS: 1 | US FAERS | |
| 156 | Phlebitis | FAERS: 1 | US FAERS | |
| 157 | Poor quality drug administered | FAERS: 1 | US FAERS | |
| 158 | Portal Vein Thrombosis | FAERS: 1 | US FAERS | |
| 159 | Prescribed overdose | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 160 | Presyncope | FAERS: 1 | US FAERS | |
| 161 | Product complaint | FAERS: 1 | US FAERS | |
| 162 | Product quality issue | FAERS: 1 | US FAERS | |
| 163 | Product size issue | FAERS: 1 | US FAERS | |
| 164 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 165 | Purpura | FAERS: 1 | US FAERS | |
| 166 | Pyloric Stenosis | FAERS: 1 | US FAERS | |
| 167 | Rales | FAERS: 1 | US FAERS | |
| 168 | Refusal of examination | FAERS: 1 | US FAERS | |
| 169 | Renal tubular necrosis | FAERS: 1 | US FAERS | |
| 170 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 171 | Rheumatoid Arthritis | FAERS: 1 | US FAERS | |
| 172 | Secretion discharge | FAERS: 1 | US FAERS | |
| 173 | Septic Shock | FAERS: 1 | US FAERS | |
| 174 | Stevens-Johnson Syndrome | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 175 | Stillbirth | FAERS: 1 | US FAERS | |
| 176 | Stridor | FAERS: 1 | US FAERS | |
| 177 | Subdural Effusion | FAERS: 1 | US FAERS | |
| 178 | Systemic Inflammatory Response Syndrome | FAERS: 1 | US FAERS | |
| 179 | Tension | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 180 | Toxic Epidermal Necrolysis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 181 | Traumatic renal injury | FAERS: 1 | US FAERS | |
| 182 | Tryptase increased | FAERS: 1 | US FAERS | |
| 183 | Ureterolithiasis | FAERS: 1 | US FAERS | |
| 184 | Vasculitis | FAERS: 1 | US FAERS | |
| 185 | Visual Impairment | FAERS: 1 | US FAERS | |
| 186 | nervous system disorder | FAERS: 1 | US FAERS | |
| 187 | Product prescribing error | Canada Vigilance: 1 | Canada Vigilance |
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