MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

fluocinolone

(UUOUOERPONYGOS-CLCRDYEYSA-N)

Structure

SMILES: OCC(=O)[C@@]1(O)[C@H](O)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F
Type(s): Investigational
Molecular Formula:: C21H26F2O6
Molecular Weight:: 412.424
Log P:: 0.5685
Hydrogen Bond Acceptor:: 6
Hydrogen Bond Donor:: 4
TPSA:: 115.06
CAS Number(s):: 807-38-5

Synonym(s)

fluocinolone

6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione

External Link(s)

MeSH	C035394
PubChem Compound	91488
ChEBI	5108
CHEMBL	CHEMBL1201390
DrugBank	DB12553
KEGG	cpd:C07006
ZINC	4097307

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Application site irritation	FAERS: 1		US FAERS
2	Application site reaction	FAERS: 1		US FAERS
3	Application site ulcer	FAERS: 1		US FAERS
4	Chemical burn of skin	FAERS: 1		US FAERS
5	Product substitution issue	FAERS: 1		US FAERS
6	Abscess			SIDER
7	Acute gastroenteritis			SIDER
8	Alopecia			SIDER
9	Arthralgia			SIDER
10	Back Pain			SIDER
11	Blepharitis			SIDER
12	Cataract			SIDER
13	Choroidal Detachment			SIDER
14	Common Cold			SIDER
15	Corneal irritation			SIDER
16	Deafness Neurosensory			SIDER
17	Dermatitis acneiform			SIDER
18	Dermatitis			SIDER
19	Device dislocation			SIDER
20	Device expulsion			SIDER
21	Diplopia			SIDER
22	Dizziness			SIDER
23	Drug Eruptions		4278287	CTD
24	Dysgeusia			SIDER
25	Ear and labyrinth disorders			SIDER
26	Ear discomfort			SIDER
27	Eczema			SIDER
28	Endophthalmitis			SIDER
29	Erythema			SIDER
30	Excoriation			SIDER
31	Eye Infection			SIDER
32	Eye irritation			SIDER
33	Eye pain			SIDER
34	Folliculitis			SIDER
35	Gastroenteritis			SIDER
36	Glaucoma			SIDER
37	Headache			SIDER
38	Hypersensitivity			SIDER
39	Hypertrichosis			SIDER
40	Implant expulsion			SIDER
41	Infection			SIDER
42	Infestation			SIDER
43	Influenza			SIDER
44	Itch burning			SIDER
45	Keratosis pilaris			SIDER
46	Lacrimation			SIDER
47	Leukoderma			SIDER
48	Malnutrition			SIDER
49	Mechanical complication of implant			SIDER
50	Medical device complication			SIDER
51	Migration of implant			SIDER
52	Miliaria			SIDER
53	Musculoskeletal discomfort			SIDER
54	Myringitis			SIDER
55	Nasopharyngitis			SIDER
56	Nausea			SIDER
57	Neck Pain			SIDER
58	Nerve injury			SIDER
59	Open wound			SIDER
60	Otitis Media			SIDER
61	Pain			SIDER
62	Panophthalmitis			SIDER
63	Papule			SIDER
64	Photophobia			SIDER
65	Posterior subcapsular cataract			SIDER
66	Procedural complication			SIDER
67	Pruritus			SIDER
68	Retinal Detachment			SIDER
69	Rhinitis			SIDER
70	Sinusitis			SIDER
71	Skin irritation			SIDER
72	Telangiectasis		4237682	CTD
73	Tympanic Membrane Perforation			SIDER
74	Vertigo			SIDER
75	Visual Impairment			SIDER
76	Visual disturbance			SIDER
77	Vitreous floaters			SIDER
78	Vitreous opacities			SIDER
79	Vomiting			SIDER
80	Wheezing			SIDER
81	Wound Complication			SIDER
82	Wound dehiscence			SIDER
83	nervous system disorder			SIDER
84	pustule			SIDER

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