MetaADEDB 2.0 @ LMMD
dorzolamide
(IAVUPMFITXYVAF-XPUUQOCRSA-N)
Structure
SMILES
CCN[C@H]1C[C@H](C)S(=O)(=O)c2c1cc(s2)S(=O)(=O)N
Type(s)
Approved
ATC code(s)
S01EC03
Molecular Formula:
C10H16N2O4S3
Molecular Weight:
324.440
Log P:
3.8648
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
2
TPSA:
151.33
CAS Number(s):
120279-96-1; 139066-77-6
Synonym(s)
1.
dorzolamide
2.
4-ethylamino-5,6-dihydro-6-methyl-7,7-dioxide-4H-thieno(2,3-b)thiopyran-2-sulfonamide
3.
5,6-dihydro-4-ethylamino-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
4.
Dorzolamide Chibret
5.
L 671152
6.
L-671,152
7.
MK 507
8.
MK-507
9.
Trusopt
10.
dorzolamide hydrochloride
11.
dorzolamide, (trans)-isomer
External Link(s)
MeSHC062765
PubChem Compound5284549
BindingDB10884
ChEBI4702
CHEMBLCHEMBL218490
DrugBankDB00869
DrugCentral949
IUPHAR/BPS Guide to PHARMACOLOGY6810
KEGGcpd:C06969
dr:D07871
Therapeutic Target DatabaseD05UYW
ZINC1530621
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 105
Canada Vigilance: 1
Canada Vigilance
US FAERS
2Eye irritationFAERS: 16SIDER
US FAERS
3Product quality issueFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
4DizzinessFAERS: 5SIDER
US FAERS
5Product substitution issueFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
6PolyneuropathyFAERS: 4US FAERS
7Feeling abnormalFAERS: 3SIDER
US FAERS
8Optic NeuropathyFAERS: 3US FAERS
9OverdoseFAERS: 3US FAERS
10Product dropper issueFAERS: 3US FAERS
11Visual ImpairmentFAERS: 3
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
12Wrong technique in product usage processFAERS: 3US FAERS
13AstheniaFAERS: 2SIDER
US FAERS
14Burning sensationFAERS: 2US FAERS
15Chest PainFAERS: 2SIDER
US FAERS
16Eye painFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
17Eyelid margin crustingFAERS: 2US FAERS
18GlaucomaFAERS: 217949534CTD
US FAERS
19HeadacheFAERS: 2SIDER
US FAERS
20Incorrect dose administeredFAERS: 2US FAERS
21Manufacturing issueFAERS: 2US FAERS
22MydriasisFAERS: 2US FAERS
23NauseaFAERS: 2SIDER
US FAERS
24PainFAERS: 2
Canada Vigilance: 1
18166407
19668763
CTD
SIDER
Canada Vigilance
US FAERS
25PallorFAERS: 2US FAERS
26Product container issueFAERS: 2US FAERS
27Product storage errorFAERS: 2US FAERS
28Product use issueFAERS: 2US FAERS
29SyncopeFAERS: 2SIDER
US FAERS
30Throat irritationFAERS: 2SIDER
US FAERS
31TremorFAERS: 2US FAERS
32Abdominal discomfortFAERS: 1US FAERS
33Accidental exposure to productFAERS: 1US FAERS
34Alanine Aminotransferase IncreasedFAERS: 1US FAERS
35AnxietyFAERS: 1SIDER
US FAERS
36Blood lactate dehydrogenase increasedFAERS: 1US FAERS
37ColitisFAERS: 1US FAERS
38Device defectiveFAERS: 1US FAERS
39Drug effect incompleteFAERS: 1US FAERS
40Drug ineffective for unapproved indicationFAERS: 1US FAERS
41DysgeusiaFAERS: 1SIDER
US FAERS
42DysuriaFAERS: 1SIDER
US FAERS
43Eye BurnsFAERS: 1US FAERS
44Eye inflammationFAERS: 1US FAERS
45Foreign body sensation in eyesFAERS: 1US FAERS
46HypersensitivityFAERS: 1SIDER
US FAERS
47HypotensionFAERS: 1SIDER
US FAERS
48Incorrect dose administered by deviceFAERS: 1US FAERS
49Joint injuryFAERS: 1US FAERS
50Limb injuryFAERS: 1US FAERS
51Lip swellingFAERS: 1US FAERS
52Loss of personal independence in daily activitiesFAERS: 1US FAERS
53MalaiseFAERS: 1US FAERS
54Medication residueFAERS: 1US FAERS
55Poor quality product administeredFAERS: 1US FAERS
56Product packaging quantity issueFAERS: 1US FAERS
57Product physical issueFAERS: 1US FAERS
58Product taste abnormalFAERS: 1US FAERS
59PruritusFAERS: 1SIDER
US FAERS
60Temperature intoleranceFAERS: 1US FAERS
61Toxic Epidermal NecrolysisFAERS: 1SIDER
US FAERS
62Urinary tract infectionFAERS: 1SIDER
US FAERS
63VomitingFAERS: 1SIDER
US FAERS
64Weight decreasedFAERS: 1SIDER
US FAERS
65prostatitisFAERS: 1US FAERS
66Abdominal PainSIDER
67AcheSIDER
68Acute Coronary SyndromeSIDER
69AgranulocytosisSIDER
70AlopeciaSIDER
71AmnesiaSIDER
72Anaphylactic shockSIDER
73Angina PectorisSIDER
74AngioedemaSIDER
75AnorexiaSIDER
76Arterial insufficiencySIDER
77Arterial thrombosisSIDER
78ArthralgiaSIDER
79Atrioventricular BlockSIDER
80Back PainSIDER
81BlepharitisSIDER
82Blood urea increasedSIDER
83BradycardiaSIDER
84Bronchial ObstructionSIDER
85BronchitisSIDER
86BronchospasmSIDER
87Cardiac ArrestSIDER
88CatatoniaSIDER
89Cerebrovascular accidentSIDER
90Choroidal DetachmentSIDER
91Cold hands & feetSIDER
92Conjunctival dischargeSIDER
93ConjunctivitisSIDER
94Corneal erosionSIDER
95DermatitisSIDER
96Device capturing issueSIDER
97DiplopiaSIDER
98DiscomfortSIDER
99DisorientationSIDER
100Disturbance in sexual arousalSIDER
101Dreaming excessiveSIDER
102DyspepsiaSIDER
103EpistaxisSIDER
104Erectile dysfunctionSIDER
105Erythema MultiformeSIDER
106ErythemaSIDER
107Eye RednessSIDER
108Eyelid irritationSIDER
109Eyelid painSIDER
110FatigueSIDER
111Follicular conjunctivitisSIDER
112Gastrointestinal PainSIDER
113Glaucoma, Open-Angle18166407
19668763
CTD
114HepatomegalySIDER
115InfluenzaSIDER
116Intermittent ClaudicationSIDER
117IridocyclitisSIDER
118KeratitisSIDER
119LacrimationSIDER
120LaryngospasmSIDER
121Local reactionSIDER
122Memory LossSIDER
123Metabolic acidosisSIDER
124Mood swingsSIDER
125Musculoskeletal discomfortSIDER
126Myasthenia GravisSIDER
127Myocardial InfarctionSIDER
128Myopia transientSIDER
129MyopiaSIDER
130NervousnessSIDER
131Ocular Hypertension

View details

CTD
132Oropharyngeal discomfortSIDER
133Oropharyngeal painSIDER
134PalpitationsSIDER
135PharyngitisSIDER
136PhotophobiaSIDER
137Psoriasis flare-upSIDER
138PsoriasisSIDER
139Punctate keratitisSIDER
140RalesSIDER
141Rash erythematousSIDER
142RednessSIDER
143Respiratory FailureSIDER
144Respiratory distressSIDER
145Retroperitoneal fibrosisSIDER
146ScabSIDER
147ScotomaSIDER
148Serum urea increasedSIDER
149ShockSIDER
150Sinoatrial BlockSIDER
151SinusitisSIDER
152Skin irritationSIDER
153SomnolenceSIDER
154Stevens-Johnson Syndrome25811541CTD
SIDER
155SweatingSIDER
156TensionSIDER
157Thrombocytopenic purpuraSIDER
158TinnitusSIDER
159UrticariaSIDER
160Vasodilation procedureSIDER
161VasodilationSIDER
162VertigoSIDER
163Visual disturbanceSIDER
164Vital dye staining cornea presentSIDER
165Vitreous DetachmentSIDER
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