MetaADEDB 2.0 @ LMMD
zotepine
(HDOZVRUNCMBHFH-UHFFFAOYSA-N)
Structure
SMILES
CN(CCOC1=Cc2ccccc2Sc2c1cc(Cl)cc2)C
Type(s)
Approved; Investigational; Withdrawn
ATC code(s)
N05AX11
Molecular Formula:
C18H18ClNOS
Molecular Weight:
331.860
Log P:
4.8809
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
37.77
CAS Number(s):
26615-21-4
Synonym(s)
1.
zotepine
2.
2-chloro-11-(2-dimethylaminoethoxy)dibenzo(b,f)thiepine
3.
Nipolept
4.
Zoleptil
External Link(s)
MeSHC022172
PubChem Compound5736
BindingDB35255
50095889
ChEBI32316
CHEMBLCHEMBL285802
DrugBankDB09225
DrugCentral2875
IUPHAR/BPS Guide to PHARMACOLOGY103
KEGGdr:D01321
Therapeutic Target DatabaseD0T6QX
ZINC2264
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Activation syndromeOFFSIDES
2Adams-Stokes SyndromeOFFSIDES
3Akathisia, Drug-Induced12107616CTD
4Alanine Aminotransferase IncreasedOFFSIDES
5Alcoholic IntoxicationOFFSIDES
6Altered state of consciousnessOFFSIDES
7AmimiaOFFSIDES
8AnorexiaOFFSIDES
9Aphthous StomatitisOFFSIDES
10Aspiration PneumoniaOFFSIDES
11Atrial thrombosisOFFSIDES
12AuraOFFSIDES
13Bacterial culture positiveOFFSIDES
14Basal Ganglia Diseases12107616
20193724		CTD
15Bipolar II disorderOFFSIDES
16Blood GlucoseOFFSIDES
17Blood alkaline phosphatase increasedOFFSIDES
18Blood creatine phosphokinase increasedOFFSIDES
19Blood creatinine increasedOFFSIDES
20Blood lactate dehydrogenase increasedOFFSIDES
21Blood osmolarity abnormalOFFSIDES
22Blood potassium increasedOFFSIDES
23Blood sodium increasedOFFSIDES
24Blood urea increasedOFFSIDES
25Catalepsy20223878CTD
26ChokingOFFSIDES
27Chronic ulcerative colitisOFFSIDES
28Congenital tricuspid valve incompetenceOFFSIDES
29DehydrationOFFSIDES
30Depressed Level of ConsciousnessOFFSIDES
31Depressed moodOFFSIDES
32Depressive disorder20223878CTD
33Diabetes InsipidusOFFSIDES
34Diet refusalOFFSIDES
35Drug toxicityOFFSIDES
36DysuriaOFFSIDES
37Electrocardiogram ST-T changeOFFSIDES
38Electrophoresis abnormalOFFSIDES
39Enzyme InhibitionOFFSIDES
40EpilepsyOFFSIDES
41ErythemaOFFSIDES
42Feeling abnormalOFFSIDES
43FrustrationOFFSIDES
44Gamma-Glutamyltransferase IncreasedOFFSIDES
45Gingival HyperplasiaOFFSIDES
46Gingival erythemaOFFSIDES
47Heat StrokeOFFSIDES
48Hip swellingOFFSIDES
49Ideas of referenceOFFSIDES
50Inappropriate affectOFFSIDES
51IndurationOFFSIDES
52LethargyOFFSIDES
53Loose toothOFFSIDES
54MegacolonOFFSIDES
55Mental disorders16856516CTD
56MurderOFFSIDES
57Nephrogenic Diabetes InsipidusOFFSIDES
58Neuroleptic Malignant SyndromeOFFSIDES
59Oropharyngeal plaqueOFFSIDES
60Pelvic venous thrombosisOFFSIDES
61PeriodontitisOFFSIDES
62PoriomaniaOFFSIDES
63Protein total decreasedOFFSIDES
64Psychiatric symptomOFFSIDES
65Psychotic Disorders20223878CTD
66Pulmonary HypertensionOFFSIDES
67Pulmonary InfarctionOFFSIDES
68Pulmonary thrombosisOFFSIDES
69Respiratory dyskinesiaOFFSIDES
70RhabdomyolysisOFFSIDES
71Rubella antibody positiveOFFSIDES
72RubellaOFFSIDES
73Schizophrenia20223878CTD
74ScreamingOFFSIDES
75Sudden deathOFFSIDES
76Therapy non-responderOFFSIDES
77Tooth ResorptionOFFSIDES
78Unevaluable eventOFFSIDES
79Venous Thrombosis9211574CTD
80Violence-related symptomOFFSIDES
81Water IntoxicationOFFSIDES
82XanthomaOFFSIDES
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