Terfenadine
(GUGOEEXESWIERI-UHFFFAOYSA-N)
Structure
- SMILES
- OC(c1ccc(cc1)C(C)(C)C)CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O
- Type(s)
- Approved; Withdrawn
- ATC code(s)
- R06AX12
- Molecular Formula:
- C32H41NO2
- Molecular Weight:
- 471.673
- Log P:
- 6.3837
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 2
- TPSA:
- 43.7
- CAS Number(s):
- 50679-08-8
Synonym(s)
1.
Terfenadine
2.
Balkis Saft Spezial
3.
Cyater
4.
Hisfedin
5.
RMI-9918
6.
Rapidal
7.
Seldane
8.
Teldane
9.
Terfedura
10.
Terfemundin
11.
Terfenadin AL
12.
Terfenadin Heumann
13.
Terfenadin Stada
14.
Terfenadin Von Ct
15.
Terfenadin-Ratiopharm
16.
Terfenidine
17.
Ternadin
18.
Triludan
19.
alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
20.
RMI 9918
21.
RMI9918
22.
Terfenadin Ratiopharm
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abdominal Pain | Canada Vigilance: 3 | Canada Vigilance | |
| 2 | Abdominal discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 3 | Acne | Canada Vigilance: 1 | Canada Vigilance | |
| 4 | Agitation | Canada Vigilance: 4 | Canada Vigilance | |
| 5 | Akathisia | Canada Vigilance: 1 | Canada Vigilance | |
| 6 | Anaphylactoid Reaction | Canada Vigilance: 2 | Canada Vigilance | |
| 7 | Angioedema | 12373280 | CTD | |
| 8 | Anticholinergic Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 9 | Anxiety | Canada Vigilance: 3 | Canada Vigilance | |
| 10 | Arthralgia | Canada Vigilance: 2 | Canada Vigilance | |
| 11 | Arthropathy | Canada Vigilance: 1 | Canada Vigilance | |
| 12 | Asthenia | Canada Vigilance: 3 | Canada Vigilance | |
| 13 | Asthma | Canada Vigilance: 1 | 8006312 | CTD Canada Vigilance |
| 14 | Bradycardia | Canada Vigilance: 1 | 9232548 22744888 | CTD Canada Vigilance |
| 15 | Cardiovascular Diseases | 12244568 | CTD | |
| 16 | Cerebrovascular accident | Canada Vigilance: 1 | Canada Vigilance | |
| 17 | Chemical and Drug Induced Liver Injury | 8757175 | CTD | |
| 18 | Chest Pain | Canada Vigilance: 2 | Canada Vigilance | |
| 19 | Chest discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 20 | Chills | Canada Vigilance: 1 | Canada Vigilance | |
| 21 | Cholestasis | 8757175 | CTD | |
| 22 | Cold sweat | Canada Vigilance: 3 | Canada Vigilance | |
| 23 | Delirium | Canada Vigilance: 1 | Canada Vigilance | |
| 24 | Disorientation | Canada Vigilance: 2 | Canada Vigilance | |
| 25 | Dizziness | Canada Vigilance: 14 | Canada Vigilance | |
| 26 | Drug Overdose | 8257958 | CTD | |
| 27 | Drug level increased | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Dysgeusia | Canada Vigilance: 1 | Canada Vigilance | |
| 29 | Dyspepsia | Canada Vigilance: 2 | Canada Vigilance | |
| 30 | Epistaxis | Canada Vigilance: 3 | Canada Vigilance | |
| 31 | Erythema | Canada Vigilance: 1 | Canada Vigilance | |
| 32 | Fatigue | Canada Vigilance: 8 | Canada Vigilance | |
| 33 | Flushing | Canada Vigilance: 3 | Canada Vigilance | |
| 34 | Headache | Canada Vigilance: 16 | Canada Vigilance | |
| 35 | Heart Diseases | 8286821 8547749 | CTD | |
| 36 | Hepatitis | 8757175 | CTD | |
| 37 | Hypercalcemia | 15872215 19806302 | CTD | |
| 38 | Hypersensitivity | 2570798 | CTD | |
| 39 | Hypokalemia | 16722159 | CTD | |
| 40 | Joint stiffness | Canada Vigilance: 1 | Canada Vigilance | |
| 41 | Lethargy | Canada Vigilance: 1 | Canada Vigilance | |
| 42 | Long QT Syndrome | CTD | ||
| 43 | Malaise | Canada Vigilance: 8 | Canada Vigilance | |
| 44 | Memory impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 45 | Nausea | Canada Vigilance: 7 | Canada Vigilance | |
| 46 | Nervousness | Canada Vigilance: 1 | Canada Vigilance | |
| 47 | Oral mucosal eruption | Canada Vigilance: 1 | Canada Vigilance | |
| 48 | Osteoporosis | 15872215 17013567 19806302 | CTD | |
| 49 | Overdose | Canada Vigilance: 1 | Canada Vigilance | |
| 50 | Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 51 | Palpitations | Canada Vigilance: 8 | Canada Vigilance | |
| 52 | Pericardial effusion | 22744888 | CTD | |
| 53 | Pruritus | Canada Vigilance: 4 | 7503405 | CTD Canada Vigilance |
| 54 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 55 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Rhinitis, Allergic, Perennial | 2476015 8201490 | CTD | |
| 57 | Sinusitis | 8382980 | CTD | |
| 58 | Sneezing | Canada Vigilance: 1 | 7503405 8100058 | CTD Canada Vigilance |
| 59 | Somnolence | Canada Vigilance: 11 | Canada Vigilance | |
| 60 | Stupor | Canada Vigilance: 2 | Canada Vigilance | |
| 61 | Syncope | Canada Vigilance: 1 | 8213879 9340542 | CTD Canada Vigilance |
| 62 | Tachycardia, Ventricular | 8984050 16697328 | CTD | |
| 63 | Tachycardia | Canada Vigilance: 6 | Canada Vigilance | |
| 64 | Torsades de Pointes |
1644069
1977935 7727886 7815014 7936480 7945604 8013320 8092653 8173153 8250668 8256756 8257958 8368797 8382980 8904547 9340542 11569530 15787309 16314854 16722159 18486227 20064605 24742750 | CTD | |
| 65 | Tremor | Canada Vigilance: 1 | 8434887 | CTD Canada Vigilance |
| 66 | Urinary Retention | 8006312 | CTD | |
| 67 | Urticaria | Canada Vigilance: 4 | CTD Canada Vigilance | |
| 68 | Vasculitis | Canada Vigilance: 1 | Canada Vigilance | |
| 69 | Ventricular Fibrillation | Canada Vigilance: 1 | 16697328 16722159 | CTD Canada Vigilance |
| 70 | Visual Impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Vomiting | Canada Vigilance: 3 | Canada Vigilance | |
| 72 | jaundice | Canada Vigilance: 3 | Canada Vigilance | |
| 73 | melanoma | 16569656 | CTD |
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