Griseofulvin
(DDUHZTYCFQRHIY-RBHXEPJQSA-N)
Structure
- SMILES
- COC1=CC(=O)C[C@H]([C@@]21Oc1c(C2=O)c(OC)cc(c1Cl)OC)C
- Type(s)
- Approved; Investigational; Vet_approved
- ATC code(s)
- D01AA08; D01BA01
- Molecular Formula:
- C17H17ClO6
- Molecular Weight:
- 352.766
- Log P:
- 2.8103
- Hydrogen Bond Acceptor:
- 6
- Hydrogen Bond Donor:
- 0
- TPSA:
- 71.06
- CAS Number(s):
- 126-07-8; 2884-22-2
Synonym(s)
1.
Griseofulvin
2.
Fulvicin-U-F
3.
Grifulvin V
4.
Gris-PEG
5.
Grisactin
6.
Grisefuline
7.
Fulvicin U F
8.
FulvicinUF
9.
Gris PEG
10.
GrisPEG
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Dizziness | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 2 | Headache | FAERS: 9 Canada Vigilance: 6 | 4408278 18378354 | CTD SIDER Canada Vigilance US FAERS |
| 3 | Lymphadenopathy | FAERS: 7 | US FAERS | |
| 4 | Stevens-Johnson Syndrome | FAERS: 6 | 25811541 | CTD US FAERS |
| 5 | Fatigue | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 6 | Cold sweat | FAERS: 3 | US FAERS | |
| 7 | Hepatomegaly | FAERS: 3 | 15446108 | CTD US FAERS |
| 8 | Malaise | FAERS: 3 | US FAERS | |
| 9 | Nausea | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance SIDER US FAERS | |
| 10 | Proteinuria | FAERS: 3 | SIDER US FAERS | |
| 11 | Pruritus | FAERS: 3 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 12 | Splenomegaly | FAERS: 3 | US FAERS | |
| 13 | Swelling | FAERS: 3 | US FAERS | |
| 14 | Activities of daily living impaired | FAERS: 2 | US FAERS | |
| 15 | Agitation | FAERS: 2 | US FAERS | |
| 16 | Arthralgia | FAERS: 2 | US FAERS | |
| 17 | Chills | FAERS: 2 | US FAERS | |
| 18 | Feeling abnormal | FAERS: 2 | SIDER US FAERS | |
| 19 | Leukopenia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 20 | Memory impairment | FAERS: 2 | US FAERS | |
| 21 | Myalgia | FAERS: 2 | US FAERS | |
| 22 | Pain | FAERS: 2 | US FAERS | |
| 23 | Rash erythematous | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 24 | Vomiting | FAERS: 2 | SIDER US FAERS | |
| 25 | Abdominal discomfort | FAERS: 1 | US FAERS | |
| 26 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 27 | Alanine Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 28 | Amnesia | FAERS: 1 | US FAERS | |
| 29 | Anorexia | FAERS: 1 | US FAERS | |
| 30 | Arthritis | FAERS: 1 | US FAERS | |
| 31 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 32 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 33 | Blood pressure orthostatic abnormal | FAERS: 1 | US FAERS | |
| 34 | Burning sensation | FAERS: 1 | US FAERS | |
| 35 | Candidiasis | FAERS: 1 | US FAERS | |
| 36 | Cheilitis | FAERS: 1 | US FAERS | |
| 37 | Chest Pain | FAERS: 1 | US FAERS | |
| 38 | Chest discomfort | FAERS: 1 | US FAERS | |
| 39 | Complement factor C3 decreased | FAERS: 1 | US FAERS | |
| 40 | Complement factor C4 decreased | FAERS: 1 | US FAERS | |
| 41 | Congenital hearing disorder | FAERS: 1 | US FAERS | |
| 42 | Conjunctivitis | FAERS: 1 | US FAERS | |
| 43 | Dehydration | FAERS: 1 | US FAERS | |
| 44 | Dermatomyositis | FAERS: 1 | US FAERS | |
| 45 | Developmental Coordination Disorder | FAERS: 1 | US FAERS | |
| 46 | Drug exposure during pregnancy | FAERS: 1 | US FAERS | |
| 47 | Drug ineffective | FAERS: 1 | US FAERS | |
| 48 | Ecchymosis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 49 | Eczema | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 50 | Enuresis | FAERS: 1 | US FAERS | |
| 51 | Epidermal necrosis | FAERS: 1 | US FAERS | |
| 52 | Exfoliative rash | FAERS: 1 | US FAERS | |
| 53 | Flatulence | FAERS: 1 | US FAERS | |
| 54 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 55 | Genital erosion | FAERS: 1 | US FAERS | |
| 56 | Hypersensitivity | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 57 | Inappropriate schedule of drug administration | FAERS: 1 | US FAERS | |
| 58 | Irritable Bowel Syndrome | FAERS: 1 | US FAERS | |
| 59 | Joint swelling | FAERS: 1 | US FAERS | |
| 60 | Lip swelling | FAERS: 1 | US FAERS | |
| 61 | Lymphocytosis | FAERS: 1 | US FAERS | |
| 62 | Medication Error | FAERS: 1 | US FAERS | |
| 63 | Mental status changes | FAERS: 1 | US FAERS | |
| 64 | Microsporum infection | FAERS: 1 | US FAERS | |
| 65 | Overdose | FAERS: 1 | US FAERS | |
| 66 | Pallor | FAERS: 1 | US FAERS | |
| 67 | Pancytopenia | FAERS: 1 | US FAERS | |
| 68 | Perivascular dermatitis | FAERS: 1 | US FAERS | |
| 69 | Personality Change | FAERS: 1 | US FAERS | |
| 70 | Product storage error | FAERS: 1 | US FAERS | |
| 71 | Psoriasis | FAERS: 1 | US FAERS | |
| 72 | Purpura | FAERS: 1 | US FAERS | |
| 73 | Screaming | FAERS: 1 | US FAERS | |
| 74 | Serum Sickness | FAERS: 1 | US FAERS | |
| 75 | Tremor | FAERS: 1 | US FAERS | |
| 76 | Trichophytosis | FAERS: 1 | US FAERS | |
| 77 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 78 | Urinary Incontinence | FAERS: 1 | US FAERS | |
| 79 | Urine bilirubin increased | FAERS: 1 | US FAERS | |
| 80 | Abdominal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 81 | Agranulocytosis | SIDER | ||
| 82 | Anemia | 2237566 | CTD | |
| 83 | Angioedema | SIDER | ||
| 84 | Asthenia | SIDER | ||
| 85 | Back Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Chemical and Drug Induced Liver Injury | CTD | ||
| 87 | Cholestasis | CTD | ||
| 88 | Depressive disorder | 19043281 | CTD | |
| 89 | Dermatitis | SIDER | ||
| 90 | Dermatomycoses | 1967699 | CTD | |
| 91 | Disseminated Intravascular Coagulation | 2084866 | CTD | |
| 92 | Dyspepsia | SIDER | ||
| 93 | Encephalitis | 2084866 | CTD | |
| 94 | Epigastric distress | SIDER | ||
| 95 | Epilepsy | 595848 | CTD | |
| 96 | Erythema Multiforme | SIDER | ||
| 97 | Erythema | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 98 | Fever | 18378354 | CTD | |
| 99 | Hematuria | 2237566 | CTD | |
| 100 | Hepatitis | 15446108 | CTD SIDER | |
| 101 | Inflammation | 12735108 | CTD | |
| 102 | Jaundice, Obstructive | 131731 | CTD | |
| 103 | Kidney Diseases | 8323253 | CTD | |
| 104 | Lethargy | Canada Vigilance: 1 | Canada Vigilance | |
| 105 | Liver Cirrhosis | 12735108 | CTD | |
| 106 | Liver Neoplasms, Experimental | 7214331 11746257 | CTD | |
| 107 | Liver neoplasms | 698038 2445643 | CTD | |
| 108 | Lupus Erythematosus, Systemic | 7577414 | CTD | |
| 109 | Mucocutaneous Lymph Node Syndrome | 8403486 | CTD | |
| 110 | Musculoskeletal stiffness | Canada Vigilance: 1 | Canada Vigilance | |
| 111 | Mycoses | 1751019 4424881 | CTD | |
| 112 | Myositis | 7572547 | CTD | |
| 113 | Nasopharyngitis | 18378354 | CTD | |
| 114 | Nephritis, Interstitial | 2237566 | CTD | |
| 115 | Nephrosis | SIDER | ||
| 116 | Nephrotic Syndrome | 7577414 | CTD SIDER | |
| 117 | Neuropathy | SIDER | ||
| 118 | Neutropenia | Canada Vigilance: 1 | Canada Vigilance | |
| 119 | Onychomycosis | 8985273 | CTD | |
| 120 | Oral candidiasis | SIDER | ||
| 121 | Palpitations | Canada Vigilance: 1 | Canada Vigilance | |
| 122 | Paresthesia | 1967699 | CTD | |
| 123 | Porphyrias, Hepatic | 1751019 6679936 19043281 | CTD | |
| 124 | Protein urine present | SIDER | ||
| 125 | Psychoses, Substance-Induced | 4408278 | CTD | |
| 126 | Pyuria | 2237566 | CTD | |
| 127 | Raynaud Disease | 5414890 | CTD | |
| 128 | Renal Insufficiency | 2237566 | CTD | |
| 129 | Somnolence | Canada Vigilance: 1 | Canada Vigilance | |
| 130 | Thrombocytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 131 | Tinea Capitis | 18378354 | CTD | |
| 132 | Tinea Pedis | 8145958 | CTD | |
| 133 | Tinea | 698038 11558553 | CTD | |
| 134 | Urticaria | Canada Vigilance: 8 | Canada Vigilance SIDER |
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