MetaADEDB 2.0 @ LMMD
Oxytocin
(XNOPRXBHLZRZKH-DSZYJQQASA-N)
Structure
SMILES
CC[C@@H]([C@@H]1NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCC(=O)N)CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N)CC(C)C)C
Molecular Formula:
C43H66N12O12S2
Molecular Weight:
1007.190
Log P:
1.5563
Hydrogen Bond Acceptor:
26
Hydrogen Bond Donor:
12
TPSA:
450.13
CAS Number(s):
50-56-6
Synonym(s)
1.
Oxytocin
External Link(s)
PubChem Compound439302
BindingDB50205990
ChEBI7872
CHEMBLCHEMBL395429
DrugCentral2042
IUPHAR/BPS Guide to PHARMACOLOGY2176
2174
KEGGcpd:C00746
dr:D00089
Therapeutic Target DatabaseD0M3FJ
D0T6FH
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 71
Canada Vigilance: 41		Canada Vigilance
OFFSIDES
US FAERS
2Drug exposure during pregnancyFAERS: 55OFFSIDES
US FAERS
3OverdoseFAERS: 16OFFSIDES
US FAERS
4Pharmaceutical product complaintFAERS: 14OFFSIDES
US FAERS
5Cerebral PalsyFAERS: 12OFFSIDES
US FAERS
6HysterectomyFAERS: 12
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
7Medication ErrorFAERS: 11
Canada Vigilance: 1		Canada Vigilance
US FAERS
8HypotensionFAERS: 10

View details

1153152
4812717
9807850
15470335
18385263
18513945
20150347
 		CTD
SIDER
US FAERS
9BradycardiaFAERS: 8
Canada Vigilance: 1		11435005CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
10Maternal exposure during pregnancyFAERS: 8US FAERS
11Disseminated Intravascular CoagulationFAERS: 7OFFSIDES
SIDER
US FAERS
12TachycardiaFAERS: 7
Canada Vigilance: 1		4812717
18385263		CTD
SIDER
Canada Vigilance
US FAERS
13Uterine RuptureFAERS: 7
Canada Vigilance: 2		7956550CTD
Canada Vigilance
US FAERS
14AsphyxiaFAERS: 5SIDER
US FAERS
15Complications of maternal exposure to therapeutic drugsFAERS: 5OFFSIDES
US FAERS
16Maternal exposure during deliveryFAERS: 5US FAERS
17Product quality issueFAERS: 5
Canada Vigilance: 5		Canada Vigilance
US FAERS
18ThrombosisFAERS: 5US FAERS
19Wrong drug administeredFAERS: 5US FAERS
20Abdominal PainFAERS: 4OFFSIDES
US FAERS
21Adverse eventFAERS: 4US FAERS
22Anaphylactic shockFAERS: 4SIDER
US FAERS
23CyanosisFAERS: 4OFFSIDES
US FAERS
24Drug administration errorFAERS: 4OFFSIDES
US FAERS
25HeadacheFAERS: 4
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
26Incorrect dose administeredFAERS: 4US FAERS
27MalaiseFAERS: 4US FAERS
28Supraventricular tachycardiaFAERS: 4US FAERS
29Accidental overdoseFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
30AnxietyFAERS: 3US FAERS
31Cardiac ArrestFAERS: 3US FAERS
32Drug exposure via breast milkFAERS: 3OFFSIDES
US FAERS
33HypoxiaFAERS: 3OFFSIDES
US FAERS
34Incorrect drug administration rateFAERS: 3
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
35LaparotomyFAERS: 3OFFSIDES
US FAERS
36UrticariaFAERS: 3US FAERS
37Uterine spasmFAERS: 3
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
38Vaginal lesionFAERS: 3OFFSIDES
US FAERS
39Wheelchair userFAERS: 3OFFSIDES
US FAERS
40treatment failureFAERS: 3US FAERS
41Accidental exposure to productFAERS: 2US FAERS
42Anaphylactoid ReactionFAERS: 2SIDER
US FAERS
43AngerFAERS: 2US FAERS
44AngioedemaFAERS: 2OFFSIDES
US FAERS
45Apparent deathFAERS: 2US FAERS
46Back PainFAERS: 2US FAERS
47Complication of deliveryFAERS: 2US FAERS
48DizzinessFAERS: 2US FAERS
49DroolingFAERS: 2US FAERS
50Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
51General physical condition abnormalFAERS: 2US FAERS
52General physical health deteriorationFAERS: 2US FAERS
53Incorrect product storageFAERS: 2US FAERS
54Infusion Site ExtravasationFAERS: 2US FAERS
55Life expectancy shortenedFAERS: 2US FAERS
56Metabolic acidosisFAERS: 2US FAERS
57Muscle SpasticityFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
58NauseaFAERS: 28251842CTD
SIDER
US FAERS
59Neonatal disorderFAERS: 2US FAERS
60OliguriaFAERS: 2OFFSIDES
US FAERS
61Oxygen saturation immeasurableFAERS: 2US FAERS
62PCO2 decreasedFAERS: 2OFFSIDES
US FAERS
63PainFAERS: 2US FAERS
64Placenta AccretaFAERS: 2OFFSIDES
US FAERS
65PruritusFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
66Respiratory distressFAERS: 2US FAERS
67RestlessnessFAERS: 2US FAERS
68Shoulder DystociaFAERS: 2OFFSIDES
US FAERS
69Suture insertionFAERS: 2OFFSIDES
US FAERS
70SwellingFAERS: 2US FAERS
71Therapy non-responderFAERS: 2US FAERS
72UnderweightFAERS: 2OFFSIDES
US FAERS
73Wrong product administeredFAERS: 2US FAERS
74Wrong technique in drug usage processFAERS: 2US FAERS
75jaundiceFAERS: 2US FAERS
76Abdominal hysterectomyFAERS: 1US FAERS
77AcidosisFAERS: 1US FAERS
78AlopeciaFAERS: 1US FAERS
79Alpha 1 foetoprotein decreasedFAERS: 1US FAERS
80Anaphylactoid syndrome of pregnancyFAERS: 1OFFSIDES
US FAERS
81Artificial rupture of membranesFAERS: 1OFFSIDES
US FAERS
82Atrial FibrillationFAERS: 1US FAERS
83Blood pH decreasedFAERS: 1US FAERS
84Blood pressure immeasurableFAERS: 1OFFSIDES
US FAERS
85Brain HypoxiaFAERS: 1US FAERS
86ChillsFAERS: 1US FAERS
87CryingFAERS: 1US FAERS
88Cytolytic hepatitisFAERS: 1US FAERS
89DeafnessFAERS: 1US FAERS
90Dermoid CystFAERS: 1US FAERS
91Device FailureFAERS: 1US FAERS
92Device infusion issueFAERS: 1US FAERS
93DiplopiaFAERS: 1US FAERS
94DiscomfortFAERS: 1US FAERS
95DissociationFAERS: 1US FAERS
96Drug abuserFAERS: 1US FAERS
97Drug dispensing errorFAERS: 1US FAERS
98Drug toxicityFAERS: 1US FAERS
99DyspareuniaFAERS: 1US FAERS
100Echocardiogram abnormalFAERS: 1OFFSIDES
US FAERS
101Electrocardiogram abnormalFAERS: 1US FAERS
102Electromechanical dissociationFAERS: 1OFFSIDES
US FAERS
103EpistaxisFAERS: 1US FAERS
104ExtravasationFAERS: 1US FAERS
105Feeding disorder neonatalFAERS: 1OFFSIDES
US FAERS
106Feeling abnormalFAERS: 1US FAERS
107Fibrin D dimer increasedFAERS: 1US FAERS
108Fluid overloadFAERS: 1SIDER
US FAERS
109FlushingFAERS: 1SIDER
US FAERS
110Forceps deliveryFAERS: 1OFFSIDES
US FAERS
111HemiparesisFAERS: 1US FAERS
112Hormone level abnormalFAERS: 1US FAERS
113Iatrogenic injuryFAERS: 1US FAERS
114Incorrect dose administered by deviceFAERS: 1US FAERS
115Incorrect route of drug administrationFAERS: 1OFFSIDES
US FAERS
116Intentional drug misuseFAERS: 1US FAERS
117LaryngospasmFAERS: 1US FAERS
118Lochial infectionFAERS: 1US FAERS
119Maternal death during childbirthFAERS: 1US FAERS
120Maternal exposure timing unspecifiedFAERS: 1US FAERS
121Mental RetardationFAERS: 1US FAERS
122Neonatal respiratory depressionFAERS: 1US FAERS
123No adverse eventFAERS: 1US FAERS
124OtotoxicityFAERS: 1US FAERS
125Oxygen consumption decreasedFAERS: 1US FAERS
126PO2 decreasedFAERS: 1OFFSIDES
US FAERS
127PallorFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
128PalpitationsFAERS: 1US FAERS
129ParesisFAERS: 1US FAERS
130Perineal injuryFAERS: 1US FAERS
131Peripheral swellingFAERS: 1US FAERS
132PneumonitisFAERS: 1US FAERS
133Post procedural complicationFAERS: 1US FAERS
134Precocious PubertyFAERS: 1US FAERS
135PresyncopeFAERS: 1US FAERS
136Procedural complicationFAERS: 1US FAERS
137Product label issueFAERS: 1US FAERS
138Product measured potency issueFAERS: 1US FAERS
139Product storage errorFAERS: 1US FAERS
140Product substitution issueFAERS: 1US FAERS
141Product use issueFAERS: 1US FAERS
142Progesterone decreasedFAERS: 1US FAERS
143Pulmonary FibrosisFAERS: 1US FAERS
144Quality of life decreasedFAERS: 1US FAERS
145RalesFAERS: 1OFFSIDES
US FAERS
146Reaction to drug excipientsFAERS: 1US FAERS
147Respiratory FailureFAERS: 1US FAERS
148RhonchiFAERS: 1OFFSIDES
US FAERS
149SomnolenceFAERS: 1US FAERS
150StillbirthFAERS: 1US FAERS
151StressFAERS: 1US FAERS
152TetanusFAERS: 1OFFSIDES
US FAERS
153Troponin increasedFAERS: 1US FAERS
154Unresponsive to stimuliFAERS: 1US FAERS
155Uterine TachysystoleFAERS: 1US FAERS
156Vaginal DischargeFAERS: 1US FAERS
157Vaginal painFAERS: 1US FAERS
158Ventilation perfusion mismatchFAERS: 1US FAERS
159VertigoFAERS: 1US FAERS
160VomitingFAERS: 18251842CTD
SIDER
US FAERS
161Water IntoxicationFAERS: 1SIDER
US FAERS
162WheezingFAERS: 1US FAERS
163Acid refluxOFFSIDES
164Acute myocardial infarctionOFFSIDES
165Acute right ventricular failureOFFSIDES
166AkinesiaOFFSIDES
167Alanine Aminotransferase IncreasedOFFSIDES
168Allergy test positiveOFFSIDES
169Amphetamine-Related Disorders19371575
19560473
20731630		CTD
170AmphetaminesOFFSIDES
171Anoxic EncephalopathyOFFSIDES
172Anticholinergic SyndromeOFFSIDES
173ApneaOFFSIDES
174AtelectasisOFFSIDES
175Atrial tachycardiaOFFSIDES
176Autistic Disorder16904652CTD
177AutomatismOFFSIDES
178Blood albumin decreasedOFFSIDES
179Blood alkaline phosphatase increasedOFFSIDES
180Blood and lymphatic system disordersSIDER
181Blood creatine phosphokinase increasedOFFSIDES
182Blood immunoglobulin EOFFSIDES
183Blood magnesium decreasedOFFSIDES
184Blood phosphorus decreasedOFFSIDES
185Bone SarcomaOFFSIDES
186Bone lesionOFFSIDES
187Brain DeathOFFSIDES
188Brain Edema1033698CTD
189CalcinosisOFFSIDES
190Cardiac Output, High1153152CTD
191Cardio-respiratory distressOFFSIDES
192Carotid pulse decreasedOFFSIDES
193Catheter related complicationOFFSIDES
194Cavernous Sinus ThrombosisOFFSIDES
195Chest Pain18385263CTD
OFFSIDES
196Choking sensationOFFSIDES
197ChordeeOFFSIDES
198ChorioamnionitisOFFSIDES
199ChylothoraxOFFSIDES
200Circumstance or information capable of leading to medication errorOFFSIDES
201ClonusOFFSIDES
202Congenital brain damageCanada Vigilance: 1Canada Vigilance
203Congenital hepatomegalyOFFSIDES
204Congenital hydronephrosisOFFSIDES
205Congenital pulmonary hypertensionOFFSIDES
206Congenital tricuspid valve incompetenceOFFSIDES
207DermatitisSIDER
208Dysmenorrhea16499031CTD
209DystoniaOFFSIDES
210Ejection Fraction DecreasedOFFSIDES
211Ejection fraction abnormalOFFSIDES
212Embolism, Amniotic Fluid7956550CTD
213End-tidal CO2 decreasedOFFSIDES
214Erythema NodosumOFFSIDES
215ErythemaOFFSIDES
216FatigueOFFSIDES
217Foaming at mouthOFFSIDES
218Fontanelle depressedOFFSIDES
219Gaze palsyOFFSIDES
220General physical conditionOFFSIDES
221GlobulinuriaOFFSIDES
222GoiterOFFSIDES
223Heart valve stenosisOFFSIDES
224Hemorrhage2629043CTD
225HistologyOFFSIDES
226HydronephrosisOFFSIDES
227HypersensitivitySIDER
228Hypertensive episodeSIDER
229HypertonicitySIDER
230Hyponatremia11871004CTD
231HyporeflexiaOFFSIDES
232HypospadiasOFFSIDES
233Hypotension, Orthostatic4673361CTD
234Incision site complicationOFFSIDES
235Increased bronchial secretionOFFSIDES
236Injection site irritationOFFSIDES
237Kidney Diseases21993003CTD
238Left Ventricular HypertrophyOFFSIDES
239Left atrial dilatationOFFSIDES
240LethargyOFFSIDES
241Live BirthOFFSIDES
242Long QT Syndrome15470335CTD
243Low Cardiac Output SyndromeOFFSIDES
244MalnutritionSIDER
245MassageOFFSIDES
246Mechanical ventilationOFFSIDES
247Morphine Dependence2991800CTD
248Musculoskeletal chest painOFFSIDES
249Musculoskeletal stiffnessOFFSIDES
250Myocardial Ischemia12859506
18385263		CTD
251NegativismOFFSIDES
252Nodule on extremityOFFSIDES
253OphthalmoplegiaOFFSIDES
254Oral infectionOFFSIDES
255OrthopneaOFFSIDES
256Oxygen supplementationOFFSIDES
257Penile Diseases

View details

1358647
1596750
2080187
2825910
3032653
7686437
7938138
8202215
10704759
11489462
11906527
 		CTD
258Peripartum cardiomyopathyOFFSIDES
259PharyngitisCanada Vigilance: 1Canada Vigilance
260PhlebitisOFFSIDES
261Pilonidal cyst congenitalOFFSIDES
262Placental InsufficiencyOFFSIDES
263PleurisyOFFSIDES
264PneumothoraxOFFSIDES
265PolyuriaOFFSIDES
266Poor sucking reflexOFFSIDES
267Portal Vein ThrombosisOFFSIDES
268Postpartum Hemorrhage11905429CTD
269Procedural hypotensionOFFSIDES
270Prothrombin time ratio decreasedOFFSIDES
271Pulmonary HypertensionOFFSIDES
272Pulmonary arterial pressure increasedOFFSIDES
273Rash erythematousCanada Vigilance: 1Canada Vigilance
274Reflex tachycardiaSIDER
275RegurgitationOFFSIDES
276Respiratory depth decreasedOFFSIDES
277Right atrial pressure increasedOFFSIDES
278Seizures27220266CTD
279ShockSIDER
280Sick Sinus SyndromeOFFSIDES
281Sinus rhythmOFFSIDES
282Skeletal injuryOFFSIDES
283Soft Tissue Injuries7956550CTD
284Spasm3752184CTD
285Splenic InfarctionOFFSIDES
286Stem cell transplantOFFSIDES
287StridorOFFSIDES
288Superficial ThrombophlebitisOFFSIDES
289Suppressed lactationCanada Vigilance: 1Canada Vigilance
OFFSIDES
290Tachycardia, Ventricular9807850
15470335		CTD
291TetanyOFFSIDES
292Therapeutic product effect decreasedCanada Vigilance: 2Canada Vigilance
293ThyroidectomyOFFSIDES
294Tongue bitingOFFSIDES
295Trisomy 21OFFSIDES
296Troponin I increasedOFFSIDES
297Troponin TOFFSIDES
298Urine amphetamine positiveOFFSIDES
299UrinomaOFFSIDES
300Uterine InversionOFFSIDES
301Uterine contractions during pregnancyOFFSIDES
302Vascular resistance systemic decreasedOFFSIDES
303Ventricular Fibrillation6071510CTD
304Ventricular hypokinesiaOFFSIDES
305Wound infection bacterialOFFSIDES
306anaphylaxis8517515CTD
307effusionSIDER
308nervous system disorderSIDER
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