Thiethylperazine
(XCTYLCDETUVOIP-UHFFFAOYSA-N)
Structure
- SMILES
- CCSc1ccc2c(c1)N(CCCN1CCN(CC1)C)c1c(S2)cccc1
- Type(s)
- Approved; Withdrawn
- ATC code(s)
- R06AD03
- Molecular Formula:
- C22H29N3S2
- Molecular Weight:
- 399.616
- Log P:
- 4.9796
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 0
- TPSA:
- 60.32
- CAS Number(s):
- 1179-69-7; 1420-55-9
Synonym(s)
1.
Thiethylperazine
2.
Norzine
3.
Thiethylperazine Malate
4.
Thiethylperazine Maleate (2:1)
5.
Torecan
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Dizziness | FAERS: 4 | US FAERS | |
| 2 | Nausea | FAERS: 4 Canada Vigilance: 1 | 514725 | CTD OFFSIDES Canada Vigilance US FAERS |
| 3 | Somnolence | FAERS: 4 | US FAERS | |
| 4 | Tachycardia | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Thirst | FAERS: 4 | US FAERS | |
| 6 | Dystonia | FAERS: 3 Canada Vigilance: 1 | CTD OFFSIDES Canada Vigilance US FAERS | |
| 7 | Dysarthria | FAERS: 2 | US FAERS | |
| 8 | Excessive eye blinking | FAERS: 2 | OFFSIDES US FAERS | |
| 9 | Hypoaesthesia facial | FAERS: 2 | OFFSIDES US FAERS | |
| 10 | Scotoma | FAERS: 2 | OFFSIDES US FAERS | |
| 11 | Torticollis | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 12 | Tremor | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Asthenia | FAERS: 1 | US FAERS | |
| 14 | Bradykinesia | FAERS: 1 | US FAERS | |
| 15 | Drug administration error | FAERS: 1 | US FAERS | |
| 16 | Dysphonia | FAERS: 1 | US FAERS | |
| 17 | Hyperpyrexia | FAERS: 1 | US FAERS | |
| 18 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 19 | Laryngospasm | FAERS: 1 | OFFSIDES US FAERS | |
| 20 | Muscle Rigidity | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 21 | Oculogyration | FAERS: 1 | US FAERS | |
| 22 | Oculogyric crisis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance OFFSIDES US FAERS | |
| 23 | Pain | FAERS: 1 | OFFSIDES US FAERS | |
| 24 | Parkinsonian crisis | FAERS: 1 | US FAERS | |
| 25 | Tardive Dyskinesia | FAERS: 1 | OFFSIDES US FAERS | |
| 26 | Abdominal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 27 | Acidosis | OFFSIDES | ||
| 28 | Agitation | Canada Vigilance: 1 | Canada Vigilance | |
| 29 | Amnesia | OFFSIDES | ||
| 30 | Amphetamines | OFFSIDES | ||
| 31 | Angioedema | 16101941 | CTD | |
| 32 | Anhedonia | OFFSIDES | ||
| 33 | Anxiety | Canada Vigilance: 1 | Canada Vigilance OFFSIDES | |
| 34 | Aortic Aneurysm | OFFSIDES | ||
| 35 | Aphthous Stomatitis | OFFSIDES | ||
| 36 | Arteriosclerosis | OFFSIDES | ||
| 37 | Ascites | OFFSIDES | ||
| 38 | Asthma | OFFSIDES | ||
| 39 | Basal Ganglia Diseases | 875594 8084830 16101941 | CTD | |
| 40 | Benign Prostatic Hyperplasia | OFFSIDES | ||
| 41 | Blood Glucose | OFFSIDES | ||
| 42 | Blood creatine phosphokinase MB increased | OFFSIDES | ||
| 43 | Blood creatine phosphokinase increased | OFFSIDES | ||
| 44 | Blood glucose fluctuation | OFFSIDES | ||
| 45 | Blood phosphorus decreased | OFFSIDES | ||
| 46 | Blood sodium | OFFSIDES | ||
| 47 | Bone lesion | OFFSIDES | ||
| 48 | Bronchitis | OFFSIDES | ||
| 49 | Bruxism | OFFSIDES | ||
| 50 | Cataract operation | OFFSIDES | ||
| 51 | Cataract | OFFSIDES | ||
| 52 | Cellulitis | OFFSIDES | ||
| 53 | Central venous catheter removal | OFFSIDES | ||
| 54 | Choking sensation | OFFSIDES | ||
| 55 | Chronic Obstructive Airway Disease | OFFSIDES | ||
| 56 | Cleft Palate | 12742335 | CTD | |
| 57 | Colectomy | OFFSIDES | ||
| 58 | Colon adenoma | OFFSIDES | ||
| 59 | Compression fracture | OFFSIDES | ||
| 60 | Contracture | OFFSIDES | ||
| 61 | Deafness | OFFSIDES | ||
| 62 | Debridement | OFFSIDES | ||
| 63 | Deglutition Disorders | 16101941 | CTD | |
| 64 | Denervation atrophy | OFFSIDES | ||
| 65 | Dental abscess | OFFSIDES | ||
| 66 | Dental caries | OFFSIDES | ||
| 67 | Denture wearer | OFFSIDES | ||
| 68 | Diabetes | OFFSIDES | ||
| 69 | Diarrhea | 9348575 | CTD | |
| 70 | Diplopia | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Diverticulosis | OFFSIDES | ||
| 72 | Drowsiness | OFFSIDES | ||
| 73 | Drug Overdose | 4184863 | CTD | |
| 74 | Dyskinesia, Drug-Induced | 8084830 16101941 | CTD | |
| 75 | Dysphemia | OFFSIDES | ||
| 76 | Ejection Fraction Decreased | OFFSIDES | ||
| 77 | Endodontic procedure | OFFSIDES | ||
| 78 | Erythema Multiforme | OFFSIDES | ||
| 79 | Erythema | 16101941 | CTD | |
| 80 | Feeling jittery | Canada Vigilance: 1 | Canada Vigilance | |
| 81 | General physical health deterioration | OFFSIDES | ||
| 82 | Globulinuria | OFFSIDES | ||
| 83 | Graft infection | OFFSIDES | ||
| 84 | Granulocytosis | OFFSIDES | ||
| 85 | Hospice Care | OFFSIDES | ||
| 86 | Intention tremor | OFFSIDES | ||
| 87 | Kidney Failure | OFFSIDES | ||
| 88 | Leukopenia neonatal | OFFSIDES | ||
| 89 | Malignant neoplasm progression | OFFSIDES | ||
| 90 | Mastication disorder | OFFSIDES | ||
| 91 | Mental status changes | OFFSIDES | ||
| 92 | Migraine Disorders | 4184863 | CTD | |
| 93 | Mouth Abnormalities | 17328645 | CTD | |
| 94 | Musculoskeletal Pain | OFFSIDES | ||
| 95 | Musculoskeletal discomfort | OFFSIDES | ||
| 96 | Musculoskeletal stiffness | Canada Vigilance: 1 | Canada Vigilance | |
| 97 | Myeloma recurrence | OFFSIDES | ||
| 98 | Myoclonus | 2475196 | CTD | |
| 99 | Nephrolithiasis | OFFSIDES | ||
| 100 | Nerve Block | OFFSIDES | ||
| 101 | Neurodermatitis | OFFSIDES | ||
| 102 | Opisthotonus | Canada Vigilance: 2 | Canada Vigilance | |
| 103 | Osteoporosis | OFFSIDES | ||
| 104 | Osteosclerosis | OFFSIDES | ||
| 105 | Parkinsonian Disorders | 15469457 | CTD | |
| 106 | Renal cyst | OFFSIDES | ||
| 107 | Respiratory Failure | OFFSIDES | ||
| 108 | Restlessness | Canada Vigilance: 1 | Canada Vigilance | |
| 109 | Retrocollis | OFFSIDES | ||
| 110 | Rhabdomyolysis | OFFSIDES | ||
| 111 | Sinusitis | OFFSIDES | ||
| 112 | Skin laceration | OFFSIDES | ||
| 113 | Skin toxicity | OFFSIDES | ||
| 114 | Speech Disorders | 16101941 | CTD | |
| 115 | Strabismus | Canada Vigilance: 1 | Canada Vigilance | |
| 116 | Stupor | Canada Vigilance: 1 | Canada Vigilance | |
| 117 | Supraventricular tachycardia | Canada Vigilance: 1 | Canada Vigilance | |
| 118 | Tendinitis | OFFSIDES | ||
| 119 | Tetany | Canada Vigilance: 1 | Canada Vigilance | |
| 120 | Tongue movement disturbance | Canada Vigilance: 1 | Canada Vigilance | |
| 121 | Tooth Extraction | OFFSIDES | ||
| 122 | Urticaria | Canada Vigilance: 1 | Canada Vigilance | |
| 123 | Vascular insufficiency | OFFSIDES | ||
| 124 | Vomiting | 514725 7147262 | CTD | |
| 125 | anaphylaxis | 16101941 | CTD |
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