MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

cisatracurium

(YXSLJKQTIDHPOT-LJCJQEJUSA-N)

Structure

SMILES: COc1cc2c(cc1OC)CC[N@+]([C@@H]2Cc1ccc(c(c1)OC)OC)(C)CCC(=O)OCCCCCOC(=O)CC[N@@+]1(C)CCc2c([C@H]1Cc1ccc(c(c1)OC)OC)cc(c(c2)OC)OC
Molecular Formula:: C53H72N2O12++
Molecular Weight:: 929.145
Log P:: 7.9831
Hydrogen Bond Acceptor:: 12
Hydrogen Bond Donor:: 0
TPSA:: 126.44
CAS Number(s):: 96946-41-7

Synonym(s)

cisatracurium

51W89

Nimbex

cisatracurium besilate

cisatracurium besylate

External Link(s)

MeSH	C101584
PubChem Compound	62887 62886
ChEBI	140621
CHEMBL	CHEMBL1201248
DrugBank	DB00565 DB13450
DrugCentral	661
ZINC	238809664

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Drug ineffective	FAERS: 3		US FAERS
2	Angioedema	FAERS: 2		OFFSIDES SIDER US FAERS
3	Bradycardia	FAERS: 2		OFFSIDES SIDER US FAERS
4	Acute Coronary Syndrome	FAERS: 1	18570839 19097966	CTD OFFSIDES US FAERS
5	Hypotension	FAERS: 1		SIDER US FAERS
6	Myopathy	FAERS: 1		SIDER US FAERS
7	Respiratory distress	FAERS: 1		US FAERS
8	Abdominal sepsis			OFFSIDES
9	Accidental exposure			OFFSIDES
10	Accidental overdose			OFFSIDES
11	Acidosis			OFFSIDES
12	Activated partial thromboplastin time shortened			OFFSIDES
13	Adnexitis			OFFSIDES
14	Adrenal mass			OFFSIDES
15	Akinesia			OFFSIDES
16	Albuminuria			OFFSIDES
17	Alkalosis			OFFSIDES
18	Allergy test positive			OFFSIDES
19	Alveolitis			OFFSIDES
20	Anal Fissure			OFFSIDES
21	Anaphylactic shock			SIDER
22	Anaphylactoid Reaction			SIDER
23	Anticholinergic Syndrome			OFFSIDES
24	Anuria			OFFSIDES
25	Apallic syndrome			OFFSIDES
26	Apnea			OFFSIDES
27	Arterial thrombosis			OFFSIDES
28	Arteriovenous fistula thrombosis			OFFSIDES
29	Ascites infection			OFFSIDES
30	Ascites			OFFSIDES
31	Atrial tachycardia			OFFSIDES
32	Blepharospasm			OFFSIDES
33	Blood Glucose			OFFSIDES
34	Blood albumin decreased			OFFSIDES
35	Blood chloride increased			OFFSIDES
36	Blood creatine phosphokinase increased			OFFSIDES
37	Blood fibrinogen increased			OFFSIDES
38	Blood glucose fluctuation			OFFSIDES
39	Blood pH decreased			OFFSIDES
40	Blood phosphorus decreased			OFFSIDES
41	Blood potassium increased			OFFSIDES
42	Blood pressure immeasurable			OFFSIDES
43	Brain Contusion			OFFSIDES
44	Brain Death			OFFSIDES
45	Bronchospasm			SIDER
46	Bulbar palsy			OFFSIDES
47	Butterfly rash			OFFSIDES
48	Cardiac Arrest			SIDER
49	Cerebral hyperperfusion syndrome			OFFSIDES
50	Cervical laser therapy			OFFSIDES
51	Chronic sinusitis			OFFSIDES
52	Circumstance or information capable of leading to medication error			OFFSIDES
53	Clonus			OFFSIDES
54	Congenital pyelocaliectasis			OFFSIDES
55	Congenital tricuspid valve incompetence			OFFSIDES
56	Conversion disorder			OFFSIDES
57	Cyanosis			OFFSIDES
58	Cytokine Release Syndrome			OFFSIDES
59	Cytolytic hepatitis			OFFSIDES
60	Depressed Level of Consciousness			OFFSIDES
61	Dermatitis			SIDER
62	Dermatomyositis			OFFSIDES
63	Developmental Coordination Disorder			OFFSIDES
64	Device ineffective			OFFSIDES
65	Duodenal atresia			OFFSIDES
66	Electrocardiogram ST-T segment depression			OFFSIDES
67	Electrocardiogram repolarisation abnormality			OFFSIDES
68	Electromechanical dissociation			OFFSIDES
69	Embolism			OFFSIDES
70	Endotracheal intubation complication			OFFSIDES
71	Enterococcal infection			OFFSIDES
72	Eosinophilic myocarditis			OFFSIDES
73	Erythema			OFFSIDES SIDER
74	Escherichia infection			OFFSIDES
75	Familial risk factor			OFFSIDES
76	Flushing			SIDER
77	Gamma-Glutamyltransferase Increased			OFFSIDES
78	Generalized flushing			SIDER
79	Glasgow coma scale			OFFSIDES
80	Globulinuria			OFFSIDES
81	Granulocytosis			OFFSIDES
82	Grip strength			OFFSIDES
83	Hepatic congestion			OFFSIDES
84	Hepatic necrosis			OFFSIDES
85	Hepatitis			OFFSIDES
86	Histamine level increased			OFFSIDES
87	Hydronephrosis			OFFSIDES
88	Hypercapnia			OFFSIDES
89	Hypersensitivity			SIDER
90	Hypoxemia			SIDER
91	Hypoxia			OFFSIDES SIDER
92	Idiosyncratic drug reaction			OFFSIDES
93	Implantable defibrillator insertion			OFFSIDES
94	Incorrect route of drug administration			OFFSIDES
95	Infantile apnoeic attack			OFFSIDES
96	Intubation			OFFSIDES
97	Kidney Failure			OFFSIDES
98	Laceration			OFFSIDES
99	Laryngospasm			OFFSIDES SIDER
100	Late metabolic acidosis of newborn			OFFSIDES
101	Mechanical ventilation			OFFSIDES
102	Metabolic acidosis			OFFSIDES
103	Monocytosis			OFFSIDES
104	Mononucleosis syndrome			OFFSIDES
105	Mucosal erosion			OFFSIDES
106	Muscle necrosis			OFFSIDES
107	Neonatal hypotension			OFFSIDES
108	Neonatal respiratory acidosis			OFFSIDES
109	Neonatal respiratory arrest			OFFSIDES
110	Neonatal respiratory failure			OFFSIDES
111	Neurological examination abnormal			OFFSIDES
112	Nodule			OFFSIDES
113	Oliguria			OFFSIDES
114	Oropharyngeal blistering			OFFSIDES
115	Ovarian enlargement			OFFSIDES
116	Overdose			OFFSIDES
117	Oxygen supplementation			OFFSIDES
118	PCO2 increased			OFFSIDES
119	Pallor			OFFSIDES
120	Piloerection			OFFSIDES
121	Pityriasis			OFFSIDES
122	Pneumothorax			OFFSIDES
123	Polyuria			OFFSIDES
124	Post procedural complication			OFFSIDES
125	Post procedural hypothyroidism			OFFSIDES
126	Priapism			OFFSIDES
127	Procedural complication			OFFSIDES
128	Propofol Infusion Syndrome			OFFSIDES
129	Prothrombin level abnormal			OFFSIDES
130	Prothrombin level decreased			OFFSIDES
131	Prothrombin time ratio decreased			OFFSIDES
132	Pruritus			SIDER
133	Quadriplegia		14722188	CTD
134	Rales			OFFSIDES
135	Red blood cell schistocytes present			OFFSIDES
136	Respiratory Failure			OFFSIDES
137	Rhabdomyolysis			OFFSIDES
138	Septic Shock			OFFSIDES
139	Serum Sickness			OFFSIDES
140	Sinus rhythm			OFFSIDES
141	Skin test positive			OFFSIDES
142	Splenic Infarction			OFFSIDES
143	Stevens-Johnson Syndrome			OFFSIDES
144	Subcutaneous Emphysema			OFFSIDES
145	Substance Withdrawal Syndrome		17251884	CTD
146	Sudden Cardiac Death			OFFSIDES
147	Superficial Thrombophlebitis			OFFSIDES
148	Suprapubic pain			OFFSIDES
149	Supraventricular tachycardia			OFFSIDES
150	Tachycardia			SIDER
151	Transaminases increased			OFFSIDES
152	Troponin I increased			OFFSIDES
153	Troponin increased			OFFSIDES
154	Tryptase increased			OFFSIDES
155	Urticaria			SIDER
156	Vasoplegia syndrome			OFFSIDES
157	Ventricular Fibrillation			OFFSIDES
158	Ventricular hypokinesia			OFFSIDES
159	Wheezing			SIDER
160	Wrong drug administered			OFFSIDES
161	anaphylaxis		9972775 18570839 19097966	CTD

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