MetaADEDB 2.0 @ LMMD
pilsicainide
(BCQTVJKBTWGHCX-UHFFFAOYSA-N)
Structure
SMILES
O=C(CC12CCCN2CCC1)Nc1c(C)cccc1C
Type(s)
Investigational
Molecular Formula:
C17H24N2O
Molecular Weight:
272.385
Log P:
3.2713
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
32.34
CAS Number(s):
88069-67-4
Synonym(s)
1.
pilsicainide
2.
1H-pyrrolizine-7a(5H)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-, hydrochloride (1:1)
3.
1H-pyrrolizine-7a(5H)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-, hydrochloride hemihydrate
4.
N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride
5.
SUN 1165
6.
SUN-1165
7.
pilsicainide hydrochloride
8.
pilsicainide hydrochloride hemihydrate
9.
pilsicainide hydrochloride hydrate
10.
tetrahydro-1H-pyrrolizine-7a(5H)-aceto-2',6'-xylidide
External Link(s)
MeSHC042288
PubChem Compound4820
BindingDB50413638
ChEBI135127
CHEMBLCHEMBL163238
DrugBankDB12712
DrugCentral2167
KEGGdr:D08377
Therapeutic Target DatabaseD0H7AV
ZINC49925459
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal PainOFFSIDES
2AcidosisOFFSIDES
3Activities of daily living impairedOFFSIDES
4AkinesiaOFFSIDES
5Altered state of consciousnessOFFSIDES
6Anal abscessOFFSIDES
7AnorexiaOFFSIDES
8Ataxia3196380CTD
9Atrial Fibrillation

View details

11900298
14658412
15655281
16075827
24653743
 		CTD
10Atrial Flutter16075827
17201857		CTD
OFFSIDES
11Atrial tachycardiaOFFSIDES
12Atrial thrombosisOFFSIDES
13BedriddenOFFSIDES
14Blood alkaline phosphatase increasedOFFSIDES
15Blood creatinine increasedOFFSIDES
16Blood glucose decreasedOFFSIDES
17Blood lactate dehydrogenase increasedOFFSIDES
18Blood sodium increasedOFFSIDES
19Blood sodiumOFFSIDES
20Blood triglycerides increasedOFFSIDES
21Blue Toe SyndromeOFFSIDES
22Chemotherapeutic drug level increasedOFFSIDES
23Coagulation test abnormalOFFSIDES
24Consciousness Disorders10987357CTD
25Contact DermatitisOFFSIDES
26DehydrationOFFSIDES
27Depressed Level of ConsciousnessOFFSIDES
28Diabetes InsipidusOFFSIDES
29DrowsinessOFFSIDES
30Eosinophilic myocarditisOFFSIDES
31ErythemaOFFSIDES
32Gamma-Glutamyltransferase IncreasedOFFSIDES
33GlaucomaOFFSIDES
34HemiplegiaOFFSIDES
35HydronephrosisOFFSIDES
36HypercapniaOFFSIDES
37HypophagiaOFFSIDES
38HypoxiaOFFSIDES
39Immunosuppressant drug level decreasedOFFSIDES
40Incorrect drug dosage form administeredOFFSIDES
41IndurationOFFSIDES
42Lymphocyte count decreasedOFFSIDES
43Mantle cell lymphomaOFFSIDES
44MicroalbuminuriaOFFSIDES
45Pericardial effusionOFFSIDES
46PeriodontitisOFFSIDES
47Pityriasis Rubra PilarisOFFSIDES
48Platelet TransfusionOFFSIDES
49Prothrombin time abnormalOFFSIDES
50Pulmonary InfarctionOFFSIDES
51Puncture site reactionOFFSIDES
52Respiratory FailureOFFSIDES
53Seizures3196380CTD
54Shunt malfunctionOFFSIDES
55Sinus bradycardiaOFFSIDES
56Subcutaneous noduleOFFSIDES
57Sudden onset of sleepOFFSIDES
58Superior Mesenteric Artery SyndromeOFFSIDES
59Tachycardia, Paroxysmal24653743CTD
60Tachycardia, Ventricular

View details

15655281
16689855
16697328
16981928
17201857
 		CTD
61Torsades de Pointes24653743CTD
62Tremor3196380CTD
63Ventricular Fibrillation14658412
16697328
17916151		CTD
OFFSIDES
64Vomiting3196380CTD
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