MetaADEDB 2.0 @ LMMD
Fluocinonide
(WJOHZNCJWYWUJD-IUGZLZTKSA-N)
Structure
SMILES
CC(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)(C)C
Type(s)
Approved; Investigational
ATC code(s)
C05AA11; D07AC08; D07CC05
Molecular Formula:
C26H32F2O7
Molecular Weight:
494.525
Log P:
2.9376
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
1
TPSA:
99.13
CAS Number(s):
356-12-7
Synonym(s)
1.
Fluocinonide
2.
Fluocinolide
3.
Fluocinolone Acetonide 21-Acetate
4.
Fluocinonide FAPG
5.
Klariderm
6.
Lidemol
7.
Lidex
8.
Lyderm
9.
Metosyn
10.
Novoter
11.
Tiamol
12.
Topsym
13.
Topsyn
14.
Topsyne
15.
Acetonide 21-Acetate, Fluocinolone
16.
FAPG, Fluocinonide
17.
Fluocinolone Acetonide 21 Acetate
External Link(s)
MeSHD005447
PubChem Compound9642
ChEBI5109
CHEMBLCHEMBL1501
DrugBankDB01047
DrugCentral1205
IUPHAR/BPS Guide to PHARMACOLOGY7078
KEGGcpd:C07007
dr:D00325
Therapeutic Target DatabaseD03ZZK
ZINC3977978
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 40OFFSIDES
US FAERS
2Burning sensationFAERS: 10US FAERS
3Application site painFAERS: 8OFFSIDES
SIDER
US FAERS
4PruritusFAERS: 7SIDER
US FAERS
5ErythemaFAERS: 6
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
SIDER
US FAERS
6Eye irritationFAERS: 6US FAERS
7Accidental exposure to productFAERS: 5US FAERS
8Application site erythemaFAERS: 5US FAERS
9Application site pruritusFAERS: 5US FAERS
10Product substitution issueFAERS: 5US FAERS
11Product quality issueFAERS: 4US FAERS
12Application site drynessFAERS: 3US FAERS
13Drug ineffective for unapproved indicationFAERS: 3US FAERS
14EczemaFAERS: 3OFFSIDES
US FAERS
15Pharmaceutical product complaintFAERS: 3OFFSIDES
US FAERS
16Skin irritationFAERS: 3US FAERS
17Application site exfoliationFAERS: 2US FAERS
18Benign neoplasm of thyroid glandFAERS: 2OFFSIDES
US FAERS
19Drug prescribing errorFAERS: 2US FAERS
20Expired product administeredFAERS: 2US FAERS
21Eye BurnsFAERS: 2OFFSIDES
US FAERS
22FatigueFAERS: 2OFFSIDES
US FAERS
23HeadacheFAERS: 2SIDER
US FAERS
24Inappropriate schedule of drug administrationFAERS: 2US FAERS
25InflammationFAERS: 2US FAERS
26Medication ErrorFAERS: 2US FAERS
27Product formulation issueFAERS: 2US FAERS
28Product physical consistency issueFAERS: 2US FAERS
29PsoriasisFAERS: 2795379
6851655
7049592		CTD
OFFSIDES
US FAERS
30Wrong technique in product usage processFAERS: 2US FAERS
31Adverse eventFAERS: 1OFFSIDES
US FAERS
32Allergy to arthropod biteFAERS: 1US FAERS
33AngerFAERS: 1US FAERS
34Application site burnFAERS: 1SIDER
US FAERS
35Application site inflammationFAERS: 1US FAERS
36Back PainFAERS: 1US FAERS
37Blood glucose decreasedFAERS: 1OFFSIDES
US FAERS
38CellulitisFAERS: 1OFFSIDES
US FAERS
39Chemical injuryFAERS: 1US FAERS
40Depressed moodFAERS: 1US FAERS
41DermatitisFAERS: 1SIDER
US FAERS
42DizzinessFAERS: 1OFFSIDES
SIDER
US FAERS
43Drug administered at inappropriate siteFAERS: 1US FAERS
44Drug administration errorFAERS: 1US FAERS
45Drug dispensing errorFAERS: 1US FAERS
46Drug effect incompleteFAERS: 1US FAERS
47Drug withdrawal syndromeFAERS: 1US FAERS
48Dry skinFAERS: 1OFFSIDES
SIDER
US FAERS
49Exposure via direct contactFAERS: 1US FAERS
50Exposure via eye contactFAERS: 1US FAERS
51Feeling abnormalFAERS: 1US FAERS
52HepatitisFAERS: 1OFFSIDES
US FAERS
53HypersensitivityFAERS: 1SIDER
US FAERS
54Incorrect drug administration durationFAERS: 1US FAERS
55Lip swellingFAERS: 1US FAERS
56MalaiseFAERS: 1US FAERS
57NasopharyngitisFAERS: 1OFFSIDES
SIDER
US FAERS
58NauseaFAERS: 1OFFSIDES
US FAERS
59PainFAERS: 1OFFSIDES
SIDER
US FAERS
60PapuleFAERS: 1US FAERS
61Peripheral swellingFAERS: 1US FAERS
62Product compounding quality issueFAERS: 1US FAERS
63Product container issueFAERS: 1US FAERS
64Product label on wrong productFAERS: 1US FAERS
65Product physical issueFAERS: 1US FAERS
66Product use in unapproved indicationFAERS: 1US FAERS
67Product use issueFAERS: 1US FAERS
68ScabFAERS: 1US FAERS
69Skin lesionFAERS: 1OFFSIDES
US FAERS
70Stasis dermatitisFAERS: 1US FAERS
71Steroid withdrawal syndromeFAERS: 1US FAERS
72Therapeutic response unexpectedFAERS: 1US FAERS
73Therapeutic response unexpected with drug substitutionFAERS: 1US FAERS
74Urinary RetentionFAERS: 1US FAERS
75UrticariaFAERS: 1US FAERS
76Weight decreasedFAERS: 1US FAERS
77Wrong drug administeredFAERS: 1US FAERS
78jaundiceFAERS: 1US FAERS
79treatment failureFAERS: 1US FAERS
80AbasiaOFFSIDES
81Abdominal PainOFFSIDES
82Abdominal adhesionsOFFSIDES
83Abdominal discomfortOFFSIDES
84Abdominal rigidityOFFSIDES
85AbscessOFFSIDES
86AcarodermatitisOFFSIDES
87Accidental overdoseOFFSIDES
88Acid refluxOFFSIDES
89AcneOFFSIDES
90Actinic keratosisOFFSIDES
91Activities of daily living impairedOFFSIDES
92Acute bronchitisOFFSIDES
93Acute respiratory failureOFFSIDES
94AdenocarcinomaOFFSIDES
95Adnexa uteri massOFFSIDES
96AmnesiaOFFSIDES
97Anal FissureOFFSIDES
98Anal FistulaOFFSIDES
99AngiolipomaOFFSIDES
100AnhedoniaOFFSIDES
101Anorectal discomfortOFFSIDES
102AnorexiaOFFSIDES
103AnuriaOFFSIDES
104AnxietyOFFSIDES
105Aortic aneurysm repairOFFSIDES
106Aphthous StomatitisOFFSIDES
107Application site reactionSIDER
108ArteriosclerosisOFFSIDES
109ArthropathyOFFSIDES
110AstheniaOFFSIDES
111AsthmaOFFSIDES
112AtherosclerosisOFFSIDES
113Atrial FlutterOFFSIDES
114AutomatismOFFSIDES
115BalanitisOFFSIDES
116Benign Prostatic HyperplasiaOFFSIDES
117BilirubinuriaOFFSIDES
118Bipolar DisorderOFFSIDES
119Blood GlucoseOFFSIDES
120Blood albumin decreasedOFFSIDES
121Blood alkaline phosphatase increasedOFFSIDES
122Blood blisterOFFSIDES
123Blood cholesterolOFFSIDES
124Blood count abnormalOFFSIDES
125Blood osmolarity decreasedOFFSIDES
126Blood thyroid stimulating hormoneOFFSIDES
127Blood triglycerides increasedOFFSIDES
128Blood urine presentOFFSIDES
129Blurred visionOFFSIDES
130Bone SarcomaOFFSIDES
131Bone lesionOFFSIDES
132BradycardiaOFFSIDES
133Brain ConcussionOFFSIDES
134Breast CystOFFSIDES
135BronchitisOFFSIDES
136CalcinosisOFFSIDES
137Cardiac FlutterOFFSIDES
138Cardiac enzymes increasedOFFSIDES
139Cardioactive drug levelOFFSIDES
140Cardioactive drug level increasedOFFSIDES
141CataractOFFSIDES
142Catheter placementOFFSIDES
143CausalgiaOFFSIDES
144Cerebral artery occlusionOFFSIDES
145Cervicobrachial syndromeOFFSIDES
146CheilitisOFFSIDES
147Chest PainOFFSIDES
148Choking sensationOFFSIDES
149Chronic left ventricular failureOFFSIDES
150Cluster HeadacheOFFSIDES
151Cold sweatOFFSIDES
152Colon adenomaOFFSIDES
153Congenital heart diseaseOFFSIDES
154Congenital tricuspid valve incompetenceOFFSIDES
155Conjunctival primary acquired melanosisOFFSIDES
156CyanosisOFFSIDES
157CystOFFSIDES
158Deafness NeurosensoryOFFSIDES
159DeafnessOFFSIDES
160DehydrationOFFSIDES
161Delusional disorder, unspecified typeOFFSIDES
162DemyelinationOFFSIDES
163Dental cariesOFFSIDES
164Dermatitis acneiformSIDER
165Dermatitis, Allergic Contact8462297
11692113		CTD
166Dermatitis, Atopic11692113CTD
167DiabetesOFFSIDES
168Diabetic FootOFFSIDES
169Diabetic NephropathyOFFSIDES
170Diabetic RetinopathyOFFSIDES
171DiarrheaOFFSIDES
172Disease recurrenceOFFSIDES
173Diverticular perforationOFFSIDES
174DiverticulitisOFFSIDES
175DrowsinessOFFSIDES
176Drug ToleranceOFFSIDES
177Drug exposure during pregnancyOFFSIDES
178Drug toxicityOFFSIDES
179Drug withdrawal headacheOFFSIDES
180Duodenal UlcerOFFSIDES
181DyspareuniaOFFSIDES
182DyspepsiaOFFSIDES
183Echocardiogram abnormalOFFSIDES
184Economic problemOFFSIDES
185Ejection Fraction DecreasedOFFSIDES
186Electrocardiogram poor R-wave progressionOFFSIDES
187Embolic strokeOFFSIDES
188Emotional distressOFFSIDES
189Escherichia infectionOFFSIDES
190ExcoriationOFFSIDES
191Exfoliative rashCanada Vigilance: 1Canada Vigilance
192Eye InfectionOFFSIDES
193Eye laser surgeryOFFSIDES
194Eye painOFFSIDES
195Fatty LiverOFFSIDES
196FibromyalgiaOFFSIDES
197Flank PainOFFSIDES
198Fluid overloadOFFSIDES
199FolliculitisOFFSIDES
SIDER
200Food PoisoningOFFSIDES
201FormicationOFFSIDES
202Gastrointestinal perforationOFFSIDES
203General physical health deteriorationOFFSIDES
204Genital HerpesOFFSIDES
205GlobulinuriaOFFSIDES
206GlycosuriaSIDER
207GoutOFFSIDES
208Graft infectionOFFSIDES
209Heparin-induced thrombocytopeniaOFFSIDES
210Hepatitis COFFSIDES
211HerniaOFFSIDES
212HoarsenessOFFSIDES
213HypertrichosisSIDER
214HypophagiaOFFSIDES
215HypoxiaOFFSIDES
216IleitisOFFSIDES
217Incision site complicationOFFSIDES
218Incision site infectionOFFSIDES
219IncontinenceOFFSIDES
220Incorrect drug administration rateOFFSIDES
221Increased upper airway secretionOFFSIDES
222InfectionSIDER
223Infective exacerbation of chronic obstructive airways diseaseOFFSIDES
224Injection site erythemaOFFSIDES
225Injection site irritationOFFSIDES
226Insulin-requiring type 2 diabetes mellitusOFFSIDES
227Intervertebral Disc DegenerationOFFSIDES
228Intestinal ObstructionOFFSIDES
229Itch burningSIDER
230Joint Range of Motion DecreasedOFFSIDES
231Joint injuryOFFSIDES
232Joint sprainOFFSIDES
233Keratitis siccaOFFSIDES
234Kidney FailureOFFSIDES
235Left Ventricular HypertrophyOFFSIDES
236Left atrial dilatationOFFSIDES
237LeukodermaSIDER
238Leukopenia neonatalOFFSIDES
239Lichen PlanusOFFSIDES
240Limb discomfortOFFSIDES
241Limb injuryOFFSIDES
242Lumbar radiculopathyOFFSIDES
243Lung hyperinflationOFFSIDES
244Lymphocytic infiltrationOFFSIDES
245MastectomyOFFSIDES
246Mental status changesOFFSIDES
247MicroalbuminuriaOFFSIDES
248MiliariaSIDER
249Mood disorder due to a general medical conditionOFFSIDES
250Multi-organ disorderOFFSIDES
251Multiple MyelomaOFFSIDES
252Multiple allergiesOFFSIDES
253Muscle WeaknessOFFSIDES
254Muscle hypertrophyOFFSIDES
255Muscle strainOFFSIDES
256Musculoskeletal chest painOFFSIDES
257Musculoskeletal discomfortOFFSIDES
258Musculoskeletal stiffnessOFFSIDES
259Mycosis FungoidesOFFSIDES
260NephrolithiasisOFFSIDES
261NoduleOFFSIDES
262Non-cardiac chest painOFFSIDES
263OliguriaOFFSIDES
264OnychoclasisOFFSIDES
265Open reduction of fractureOFFSIDES
266Open woundOFFSIDES
267Optic Disc EdemaOFFSIDES
268Oral infectionOFFSIDES
269Oral mucosal exfoliationOFFSIDES
270Oropharyngeal blisteringOFFSIDES
271OrthopneaOFFSIDES
272Osteitis DeformansOFFSIDES
273OsteomaOFFSIDES
274OsteomyelitisOFFSIDES
275OsteopeniaOFFSIDES
276OsteoporosisOFFSIDES
277Ovarian adhesionOFFSIDES
278PancreatitisOFFSIDES
279ParaplegiaOFFSIDES
280Partner stressOFFSIDES
281Pathogen resistanceOFFSIDES
282PeriarthritisOFFSIDES
283Pericardial effusionOFFSIDES
284PeriodontitisOFFSIDES
285Peripheral nerve lesionOFFSIDES
286Perirectal abscessOFFSIDES
287PeritonitisOFFSIDES
288PlasmapheresisOFFSIDES
289Polymyalgia RheumaticaOFFSIDES
290Porphyria non-acuteOFFSIDES
291Postoperative constipationOFFSIDES
292Postoperative renal failureOFFSIDES
293Precancerous skin lesionOFFSIDES
294Progesterone receptor assayOFFSIDES
295Pulmonary HypertensionOFFSIDES
296Pulmonary toxicityOFFSIDES
297Pustular psoriasisOFFSIDES
298QRS axis abnormalOFFSIDES
299Renal artery occlusionOFFSIDES
300Renal tubular necrosisOFFSIDES
301Retinal Vascular DisorderOFFSIDES
302Retinal vascular occlusionOFFSIDES
303RetrocollisOFFSIDES
304RhinorrheaOFFSIDES
305SalpingitisOFFSIDES
306Scan abdomen abnormalOFFSIDES
307SclerodermaOFFSIDES
308Scrotal InfectionOFFSIDES
309SequestrectomyOFFSIDES
310Shoulder PainOFFSIDES
311Sick Sinus SyndromeOFFSIDES
312Sinus headacheOFFSIDES
313SinusitisOFFSIDES
314Skin WrinklingOFFSIDES
315Skin graft failureOFFSIDES
316Skin hypertrophyOFFSIDES
317Skin tightnessSIDER
318Spinal column stenosisOFFSIDES
319SpondylolisthesisOFFSIDES
320Spousal AbuseOFFSIDES
321Stem cell transplantOFFSIDES
322Stevens-Johnson SyndromeOFFSIDES
323StressOFFSIDES
324Subcutaneous noduleOFFSIDES
325Sudden deathOFFSIDES
326Sweat gland infectionOFFSIDES
327SwellingSIDER
328Synovial CystOFFSIDES
329Telangiectasis952530CTD
330Temperature regulation disorderOFFSIDES
331Temporal ArteritisOFFSIDES
332Tooth ExtractionOFFSIDES
333Tooth LossOFFSIDES
334Troponin increasedOFFSIDES
335Tympanic Membrane PerforationOFFSIDES
336UlcerOFFSIDES
337Unevaluable eventOFFSIDES
338Urinary Tract PainOFFSIDES
339Urine ketone body presentOFFSIDES
340Vascular graft complicationOFFSIDES
341Venous InsufficiencyOFFSIDES
342Ventricular hypokinesiaOFFSIDES
343Vertebral column massOFFSIDES
344Viral upper respiratory tract infectionOFFSIDES
345Visual disturbanceOFFSIDES
346Walking aid userOFFSIDES
347Weight GainOFFSIDES
348Wolff-Parkinson-White SyndromeOFFSIDES
349Wound ComplicationOFFSIDES
350colonoscopyOFFSIDES
351effusionOFFSIDES
352furuncleOFFSIDES
353nervous system disorderSIDER
354prostatitisOFFSIDES
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