MetaADEDB 2.0 @ LMMD
Histamine
(NTYJJOPFIAHURM-UHFFFAOYSA-N)
Structure
SMILES
NCCc1cnc[nH]1
Type(s)
Approved; Investigational
ATC code(s)
L03AX14; V04CG03
Molecular Formula:
C5H9N3
Molecular Weight:
111.145
Log P:
0.6112
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
2
TPSA:
54.7
CAS Number(s):
51-45-6; 65592-96-3
Synonym(s)
1.
Histamine
2.
Ceplene
3.
Histamine Dihydrochloride
4.
Histamine Hydrochloride
5.
Peremin
External Link(s)
MeSHD006632
PubChem Compound774
BindingDB22861
7966
22554
50121205
ChEBI18295
CHEMBLCHEMBL90
DrugBankDB05381
DrugCentral1375
IUPHAR/BPS Guide to PHARMACOLOGY1247
1204
KEGGcpd:C00388
dr:D08040
Therapeutic Target DatabaseD04USC
ZINC388081
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal CrampsSIDER
2Abdominal PainSIDER
3Anaphylactic shockSIDER
4Angioedema2443044CTD
5AnorexiaSIDER
6AnxietySIDER
7ArthralgiaSIDER
8AstheniaSIDER
9Asthma, Aspirin-Induced2443044CTD
10Asthma16344897
16387687
19363516		CTD
SIDER
11Atherosclerosis25020133CTD
12Back PainSIDER
13Blood and lymphatic system disordersSIDER
14Bone Resorption14751566CTD
15BronchoconstrictionSIDER
16BronchospasmSIDER
17Catatonia4477392CTD
18Chemical and Drug Induced Liver Injury22926047CTD
19Chest PainSIDER
20Chest discomfortCanada Vigilance: 1Canada Vigilance
21ChillsCanada Vigilance: 1Canada Vigilance
SIDER
22ConstipationSIDER
23DehydrationSIDER
24DermatitisSIDER
25DiscomfortSIDER
26DizzinessSIDER
27Dry skinSIDER
28DysgeusiaSIDER
29DyspepsiaSIDER
30Dyspnea3230472CTD
31Ear and labyrinth disordersSIDER
32Edema23872256
25656915
27474066		CTD
33EncephalitisCanada Vigilance: 1Canada Vigilance
34Eosinophilia12689652CTD
SIDER
35ErythemaCanada Vigilance: 174166CTD
SIDER
Canada Vigilance
36FatigueSIDER
37Feeling ColdCanada Vigilance: 1Canada Vigilance
38Feeling abnormalSIDER
39FlushingCanada Vigilance: 5Canada Vigilance
SIDER
40GastritisSIDER
41HeadacheCanada Vigilance: 38866624CTD
SIDER
Canada Vigilance
42Hyperalgesia18234883
21521205		CTD
43Hypersensitivity11160071CTD
SIDER
44Hypotension

View details

1033105
1899682
2439840
14051999
 		CTD
SIDER
45HypothyroidismSIDER
46InfectionSIDER
47InfestationSIDER
48Inflammation23872256CTD
49Injection Site ReactionSIDER
50Injection site bruisingSIDER
51Injection site dermatitisSIDER
52Injection site erythemaSIDER
53Injection site fibrosisSIDER
54Injection site granulomaSIDER
55Injection site inflammationSIDER
56Injection site painSIDER
57Injection site pruritusSIDER
58Injection site urticariaSIDER
59Intestinal Diseases17729160CTD
60LeukopeniaSIDER
61MalaiseSIDER
62MalnutritionSIDER
63Memory Disorders19215234CTD
64Migraine Disorders8866624CTD
65Musculoskeletal discomfortSIDER
66MyalgiaSIDER
67Myocardial Infarction16009787CTD
68NauseaSIDER
69NeutropeniaSIDER
70Night sweatsSIDER
71Pain, Postoperative8123399CTD
72Pain18155693
19552055		CTD
SIDER
73PalpitationsSIDER
74PneumoniaSIDER
75Pruritus

View details

74166
8707580
18789837
19652466
22855946
 		CTD
SIDER
76Radiation Injuries, Experimental17729160CTD
77Respiratory Hypersensitivity12095164CTD
78Rhinitis12689652CTD
79Seizures16914292CTD
80Shock, Hemorrhagic1285366CTD
81ShockSIDER
82StomatitisSIDER
83TachycardiaCanada Vigilance: 1Canada Vigilance
SIDER
84ThrombocytopeniaSIDER
85Ulcer2062949CTD
86UrticariaCanada Vigilance: 218298128CTD
SIDER
Canada Vigilance
87Vasomotor collapseSIDER
88VertigoSIDER
89VomitingSIDER
90Weight decreasedSIDER
91WeltsSIDER
92WheezingSIDER
93melanoma17709802CTD
94nervous system disorderSIDER
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