MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Puromycin Aminonucleoside

(RYSMHWILUNYBFW-GRIPGOBMSA-N)

Structure

SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1N)O)n1cnc2c1ncnc2N(C)C
Molecular Formula:: C12H18N6O3
Molecular Weight:: 294.310
Log P:: -0.8295
Hydrogen Bond Acceptor:: 9
Hydrogen Bond Donor:: 3
TPSA:: 122.55
CAS Number(s):: 58-60-6

Synonym(s)

Puromycin Aminonucleoside

3'-Amino-3'-deoxy-N,N-dimethyladenosine

Aminonucleoside

3' Amino 3' deoxy N,N dimethyladenosine

Aminonucleoside, Puromycin

External Link(s)

MeSH	D011692
PubChem Compound	6020
ChEBI	42839
CHEMBL	CHEMBL1233071
ZINC	3875394

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Acute kidney injury	3653576 10718277 22005293	CTD
2	Agammaglobulinemia	3233791	CTD
3	Albuminuria	View details 1453496 6848563 8107960 9507238 9527400 10409307 14752241 15684566 17890881 18367845 20438795	CTD
4	Ascites	View details 2236972 2267444 12972712 15075188 19885019 20613715	CTD
5	Azotemia	2236972 9165371	CTD
6	Bone Resorption	9154658	CTD
7	Edema	View details 2236972 2267444 7595070 12813006	CTD
8	Glomerulonephritis	11549609	CTD
9	Heart Diseases	16910158	CTD
10	Hypercholesterolemia	View details 2236972 2267444 8319760 8648930 8822086 9399633 9527400 10468195 12269381 12836089 15740732 16574160 20540862	CTD
11	Hyperlipoproteinemias	7595070	CTD
12	Hypertriglyceridemia	View details 2236972 2267444 8822086 12836089	CTD
13	Hypoalbuminemia	View details 8107960 8319760 9399633 9507238 12269381 15075188	CTD
14	Hypoproteinemia	View details 2236972 2267444 7648424 8107960 8446257 9154658 12269381	CTD
15	Hypoxia	15579441	CTD
16	Kidney Diseases	View details 1585386 2386429 2407887 2769936 2978121 3449640 3517267 7551005 7881871 8301930 8331284 8412499 8825380 8995747 9688461 11007821 11041286 12012391 12386277 12397044 12495295 14675041 14993511 15351692 16382022 16598202 16910158 17667850 19357181 19594554 19617259 19671594 19761811 20438795	CTD
17	Kidney Failure, Chronic	3323599 15039144 21937979	CTD
18	Liver Cirrhosis, Experimental	16570917	CTD
19	Necrosis	19452240	CTD
20	Nephritis, Interstitial	View details 3258389 8635280 10718277 10803761	CTD
21	Nephrosis	View details 839733 933467 1186127 1328752 1375300 1415478 1418851 1479717 1614035 1744988 1762292 1797743 1990206 2046802 2051647 2058701 2156648 2183627 2268473 2273594 2372813 2441105 2443012 2945356 3107051 3301049 3412819 3450901 3538253 3572200 3669494 3789094 3794548 3898001 3948917 6358456 6389977 6438895 6618773 7056851 7321525 7595070 7671567 7752581 7756592 7952147 8072247 8212539 8289993 8384958 8400078 8413769 8446257 8485924 8497129 8548034 8648930 8773353 8780404 8822086 8887289 8918620 8919236 9027795 9165371 9175058 9250166 9279205 9294829 9327748 9507238 9527400 9732237 9824428 10226349 10394110 10409307 10468195 10510332 10721075 10845833 10867541 10972674 11058564 11078415 11150858 11170791 11181809 11274237 11509803 11576343 11936424 11961407 12032185 12374619 12386276 12402553 12660332 12709412 12813006 12836089 12845231 13677671 14559718 14714169 14738908 14966466 15031335 15113391 15149336 15197181 15363039 15590761 15684566 15740732 15829708 16014031 16079985 16152783 16267158 16396944 16410268 16418842 16452496 16574160 16609681 16711654 17577743 17599817 18256598 18367650 18367845 18509322 18541230 18725544 19079321 19194550 19264907 19297354 19338138 19443634 19509464 19955829 20071462 20540862 20588063 25096716	CTD
22	Nephrotic Syndrome	View details 1104792 1281619 1318808 1320716 1436298 1462003 1591361 1636744 1647923 2175683 2212002 2236972 2267444 2646411 2725289 3233791 3258389 3323599 3827821 4719760 6246912 6471809 6497855 6848563 7066357 7101279 7172499 7442475 7648424 7810534 8023968 8107960 8319760 8412754 8413767 8494056 8506949 8692015 8704109 8959623 9059516 9154656 9154658 9171944 9249603 9270976 9399633 9507218 9732237 10025624 11012881 11055549 11451384 11675400 12191963 12269381 12653683 12806184 12972712 14672755 15075188 15496159 15579441 16020936 16204272 17035944 17457379 17803470 19885019 20407477 20613715 20649959 20685819	CTD
23	Oliguria	839733 9165371	CTD
24	Prostatic Diseases	15385636	CTD
25	Proteinuria	View details 839733 933467 1104792 1186127 1320716 1375300 1436298 1462003 1614035 1708786 1744988 1797743 1942778 2046802 2156648 2183627 2236972 2242316 2250404 2267444 2273594 2372813 2526952 2646411 2823616 2848972 3257912 3258389 3361753 3538253 3572200 3653576 3669494 3694323 3789094 3827821 3898001 3948917 3990093 4009023 6389977 6438895 6454943 6471809 7056851 7321525 7583048 7648424 7671567 7742222 7752581 7756592 7810534 7881871 7919151 7952147 8107960 8289993 8319760 8446257 8494056 8506949 8821819 8822086 8864728 8887289 8919236 8958702 8959623 9013444 9154658 9175058 9249603 9250166 9294829 9355075 9399633 9527400 10193809 10394110 10468195 10510332 10594785 10718277 10721075 10792613 10803761 10845833 11058564 11150858 11274237 11576343 11744811 11936424 11961407 11981059 12032185 12065681 12191963 12269381 12397044 12495295 12501893 12653683 12709412 12813006 12836089 12845231 12972712 14559718 14714169 14736954 14752241 14966466 15031335 15039144 15075188 15113391 15197181 15363039 15590761 15684566 15740732 15744817 15872075 16079985 16267158 16396944 16452496 16574160 16609681 16910158 17035936 17457379 17599817 17667850 17803470 18367845 18509322 19079321 19194550 19297354 19338138 19357181 19443634 19452240 19594554 19955829 20071462 20502051 20540862 20588063 20613715 25096716	CTD
26	Renal Insufficiency	7648424	CTD
27	Segmental glomerulosclerosis	2242316	CTD
28	Ventricular Dysfunction, Left	16910158	CTD

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