Succinylcholine
(YOEWQQVKRJEPAE-UHFFFAOYSA-L)
Structure
- SMILES
- O=C(OCC[N+](C)(C)C)CCC(=O)OCC[N+](C)(C)C.[Cl-].[Cl-]
- Molecular Formula:
- C14H30Cl2N2O4
- Molecular Weight:
- 361.305
- Log P:
- -5.7266
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 0
- TPSA:
- 52.6
- CAS Number(s):
- 71-27-2
Synonym(s)
1.
Succinylcholine
2.
Succinyldicholine
3.
Suxamethonium
4.
Anectine
5.
Celocurine
6.
Dicholine Succinate
7.
Ditilin
8.
Listenon
9.
Lysthenon
10.
Myorelaxin
11.
Quelicin
12.
Succicuran
13.
Succinylcholine Chloride
14.
Succinylcholine Dibromide
15.
Succinylcholine Dichloride
16.
Succinylcholine Dichloride, Di-H2O
17.
Succinylcholine Diiodide
18.
Succinylcholine Diperchlorate
19.
Succinylcholine Iodide
20.
Suxamethonium Bromide
21.
Suxamethonium Chloride
22.
Bromide, Suxamethonium
23.
Dibromide, Succinylcholine
24.
Dichloride, Succinylcholine
25.
Diiodide, Succinylcholine
26.
Diperchlorate, Succinylcholine
27.
Succinate, Dicholine
28.
Succinylcholine Dichloride, Di H2O
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 45 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 2 | Cardio-respiratory distress | FAERS: 8 | US FAERS | |
| 3 | Hypotension | FAERS: 8 | US FAERS | |
| 4 | Post procedural complication | FAERS: 7 | US FAERS | |
| 5 | Bronchospasm | FAERS: 6 | US FAERS | |
| 6 | Toxicity to various agents | FAERS: 6 | US FAERS | |
| 7 | Cardiac Arrest | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 8 | Hypoxia | FAERS: 5 | US FAERS | |
| 9 | Medication Error | FAERS: 5 | US FAERS | |
| 10 | Pharmaceutical product complaint | FAERS: 4 | US FAERS | |
| 11 | Bradycardia | FAERS: 3 | US FAERS | |
| 12 | Drug exposure during pregnancy | FAERS: 3 | US FAERS | |
| 13 | Incorrect product storage | FAERS: 3 | US FAERS | |
| 14 | Tachycardia | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 15 | Asthenia | FAERS: 2 | US FAERS | |
| 16 | Drug administration error | FAERS: 2 | US FAERS | |
| 17 | Endotracheal intubation complication | FAERS: 2 | US FAERS | |
| 18 | Flushing | FAERS: 2 | US FAERS | |
| 19 | Product measured potency issue | FAERS: 2 | US FAERS | |
| 20 | Pseudocholinesterase deficiency | FAERS: 2 | US FAERS | |
| 21 | Abasia | FAERS: 1 | US FAERS | |
| 22 | Amyotrophic Lateral Sclerosis | FAERS: 1 | US FAERS | |
| 23 | Asphyxia | FAERS: 1 | US FAERS | |
| 24 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 25 | Blood creatinine abnormal | FAERS: 1 | US FAERS | |
| 26 | Blood glucose increased | FAERS: 1 | US FAERS | |
| 27 | Blood pH decreased | FAERS: 1 | US FAERS | |
| 28 | Blood potassium increased | FAERS: 1 | US FAERS | |
| 29 | Bowel movement irregularity | FAERS: 1 | US FAERS | |
| 30 | Breech Presentation | FAERS: 1 | US FAERS | |
| 31 | Bronchial Obstruction | FAERS: 1 | US FAERS | |
| 32 | Chest Pain | FAERS: 1 | US FAERS | |
| 33 | Chest discomfort | FAERS: 1 | US FAERS | |
| 34 | Cyanosis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 35 | Diplegia | FAERS: 1 | US FAERS | |
| 36 | Drug effect delayed | FAERS: 1 | US FAERS | |
| 37 | Drug effect incomplete | FAERS: 1 | US FAERS | |
| 38 | Drug level increased | FAERS: 1 | US FAERS | |
| 39 | Electrocardiogram T wave peaked | FAERS: 1 | US FAERS | |
| 40 | Erythema | FAERS: 1 | US FAERS | |
| 41 | Immobile | FAERS: 1 | US FAERS | |
| 42 | Incorrect storage of drug | FAERS: 1 | US FAERS | |
| 43 | Lethargy | FAERS: 1 | US FAERS | |
| 44 | Limb injury | FAERS: 1 | US FAERS | |
| 45 | Mental status changes | FAERS: 1 | US FAERS | |
| 46 | Muscle Rigidity | FAERS: 1 | US FAERS | |
| 47 | Muscle tightness | FAERS: 1 | US FAERS | |
| 48 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 49 | Myalgia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 50 | Nerve stimulation test abnormal | FAERS: 1 | US FAERS | |
| 51 | Obstetric procedure complication | FAERS: 1 | US FAERS | |
| 52 | PCO2 decreased | FAERS: 1 | US FAERS | |
| 53 | Palpitations | FAERS: 1 | US FAERS | |
| 54 | Petechiae | FAERS: 1 | US FAERS | |
| 55 | Pharyngolaryngeal Pain | FAERS: 1 | US FAERS | |
| 56 | Pneumothorax | FAERS: 1 | US FAERS | |
| 57 | Poor quality drug administered | FAERS: 1 | US FAERS | |
| 58 | Procedural complication | FAERS: 1 | US FAERS | |
| 59 | Product quality issue | FAERS: 1 | US FAERS | |
| 60 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 61 | Pulmonary congestion | FAERS: 1 | US FAERS | |
| 62 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 63 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 64 | Rhabdomyolysis | FAERS: 1 | US FAERS | |
| 65 | Sepsis | FAERS: 1 | US FAERS | |
| 66 | Stridor | FAERS: 1 | US FAERS | |
| 67 | Therapy non-responder | FAERS: 1 | US FAERS | |
| 68 | Transaminases increased | FAERS: 1 | US FAERS | |
| 69 | Trismus | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 70 | Asthma | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Enzyme abnormality | Canada Vigilance: 1 | Canada Vigilance | |
| 72 | Hyperpyrexia | Canada Vigilance: 1 | Canada Vigilance | |
| 73 | Laryngospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 74 | Myositis | Canada Vigilance: 1 | Canada Vigilance | |
| 75 | Pain | Canada Vigilance: 2 | Canada Vigilance | |
| 76 | Paresis | Canada Vigilance: 1 | Canada Vigilance | |
| 77 | Product container seal issue | Canada Vigilance: 1 | Canada Vigilance |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120239
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.