MetaADEDB 2.0 @ LMMD
hydrocortisone-17-butyrate
(BMCQMVFGOVHVNG-TUFAYURCSA-N)
Structure
SMILES
CCCC(=O)O[C@@]1(CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C)C(=O)CO
Type(s)
Approved; Vet_approved
ATC code(s)
D07AB02; D07BB04
Molecular Formula:
C25H36O6
Molecular Weight:
432.550
Log P:
3.1326
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
100.9
CAS Number(s):
13609-67-1
Synonym(s)
1.
hydrocortisone-17-butyrate
2.
Locoid
3.
cortisol 17-butyrate
4.
hydrocortisone 17-butyrate
5.
hydrocortisone butyrate
External Link(s)
MeSHC007975
PubChem Compound26133
BindingDB323672
ChEBI31674
CHEMBLCHEMBL1683
DrugBankDB14540
DrugCentral3959
KEGGdr:D01619
ZINC3977794
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Application site erythemaFAERS: 5US FAERS
2Drug ineffectiveFAERS: 5US FAERS
3Product use in unapproved indicationFAERS: 4US FAERS
4UrticariaFAERS: 4US FAERS
5AngioedemaFAERS: 3US FAERS
6Application site painFAERS: 2US FAERS
7CellulitisFAERS: 2US FAERS
8ChillsFAERS: 2US FAERS
9EczemaFAERS: 2US FAERS
10GlaucomaFAERS: 2OFFSIDES
US FAERS
11Incorrect route of drug administrationFAERS: 2US FAERS
12LymphadenopathyFAERS: 2US FAERS
13LymphangitisFAERS: 2US FAERS
14Product quality issueFAERS: 2US FAERS
15PruritusFAERS: 2US FAERS
16Skin tightnessFAERS: 2US FAERS
17Accidental exposure to productFAERS: 1US FAERS
18Application site acneFAERS: 1US FAERS
19Application site drynessFAERS: 1US FAERS
20Application site irritationFAERS: 1US FAERS
21Application site pruritusFAERS: 1US FAERS
22Application site rashFAERS: 1US FAERS
23Application site reactionFAERS: 1US FAERS
24Application site swellingFAERS: 1US FAERS
25ArthralgiaFAERS: 1US FAERS
26Blood growth hormone decreasedFAERS: 1US FAERS
27Burning sensationFAERS: 1US FAERS
28CataractFAERS: 1US FAERS
29CystFAERS: 1US FAERS
30Drug administered at inappropriate siteFAERS: 1US FAERS
31Drug dose omissionFAERS: 1US FAERS
32Dry skinFAERS: 1US FAERS
33Epidural lipomatosisFAERS: 1US FAERS
34ErythemaFAERS: 1OFFSIDES
US FAERS
35Expired product administeredFAERS: 1US FAERS
36FatigueFAERS: 1US FAERS
37HeadacheFAERS: 1US FAERS
38Lip swellingFAERS: 1US FAERS
39NauseaFAERS: 1US FAERS
40No adverse eventFAERS: 1US FAERS
41Oral mucosal erythemaFAERS: 1US FAERS
42PainFAERS: 1US FAERS
43ParaparesisFAERS: 1US FAERS
44Product use issueFAERS: 1US FAERS
45SomnolenceFAERS: 1US FAERS
46Steroid withdrawal syndromeFAERS: 1US FAERS
47Therapeutic product ineffectiveFAERS: 1US FAERS
48Therapeutic response unexpectedFAERS: 1US FAERS
49Abdominal PainOFFSIDES
50Actinic keratosisOFFSIDES
51AdenocarcinomaOFFSIDES
52AlopeciaOFFSIDES
53Anal abscessOFFSIDES
54AnalgesiaOFFSIDES
55AnorexiaOFFSIDES
56Anticonvulsant drug level decreasedOFFSIDES
57Anticonvulsant drug level increasedOFFSIDES
58ApathyOFFSIDES
59Aspiration PneumoniaOFFSIDES
60BlepharitisOFFSIDES
61Blood lactate dehydrogenase increasedOFFSIDES
62Blood urea increasedOFFSIDES
63Bone marrow toxicityOFFSIDES
64BradycardiaOFFSIDES
65BursitisOFFSIDES
66CholecystitisOFFSIDES
67Cold sweatOFFSIDES
68Conjunctival depositOFFSIDES
69Contact DermatitisOFFSIDES
70CyanosisOFFSIDES
71DehydrationOFFSIDES
72Dermatitis, Allergic Contact11692113
18761609
CTD
73Dermatitis, Atopic6357892
11692113
CTD
74Drug Eruptions133840CTD
75Eye painOFFSIDES
76Eyelids pruritusOFFSIDES
77Fat necrosisOFFSIDES
78Fatty LiverOFFSIDES
79Febrile bone marrow aplasiaOFFSIDES
80Feeling of body temperature changeOFFSIDES
81HyperlipasaemiaOFFSIDES
82Impaired work abilityOFFSIDES
83LacerationOFFSIDES
84Leukopenia neonatalOFFSIDES
85LymphomaOFFSIDES
86Multiple SclerosisOFFSIDES
87MumpsOFFSIDES
88Musculoskeletal discomfortOFFSIDES
89NeuralgiaOFFSIDES
90NoduleOFFSIDES
91PanniculitisOFFSIDES
92ParakeratosisOFFSIDES
93ParanoiaOFFSIDES
94PsoriasisOFFSIDES
95Pulmonary congestionOFFSIDES
96PyelonephritisOFFSIDES
97RhabdomyolysisOFFSIDES
98Sick Sinus SyndromeOFFSIDES
99Sinus headacheOFFSIDES
100Skin test positiveOFFSIDES
101StridorOFFSIDES
102SubileusOFFSIDES
103TonsillitisOFFSIDES
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